Obtained from N-acetyl-heparin by the method of Nagasawa et al (Carbohydrate Research 58 (1977) 47-55). Totally resistant to heparinase I, substrate for heparinases IIA thrombin and activated X factor inhibitor
Obtained from N-acetyl-heparin by the method of Nagasawa et al (Carbohydrate Research 58 (1977) 47-55). Totally resistant to heparinase I, substrate for heparinases II A thrombin and activated X factor inhibitor
规格
规格或纯度
试剂级
英文名称
N-Acetyl-de-O-sulfated heparin (Heparin IV-A) sodium salt
生化机理
N-Acetyl-de-O-sulfated heparin sodium salt 是一种酶底物,可通过抗凝血酶(AT)依赖机制使凝血酶失活,进而阻止纤维粘连蛋白的形成。N-Acetyl-de-O-sulfated heparin sodium salt 还能抑制活化 X 因子(Xa 因子)。