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萘啶酮酸钠(Nalidixic acid sodium salt)是一种喹诺酮类抗生素,通过抑制细菌DNA促旋酶和拓扑异构酶IV的活性,可逆性地阻断易感细菌的DNA复制,从而发挥抗菌作用。其对革兰氏阴性菌具有较强的抗菌活性,在较低浓度下表现为抑菌作用,较高浓度下则具有杀菌效果。 本品为1%即用型溶液,常用于微生物选择性培养基的添加剂,以抑制非目标菌群的生长,广泛适用于细菌学研究和微生物检测等实验场景。
Nalidixic acid sodium salt is a quinolone antibiotic that exerts its antibacterial activity by reversibly inhibiting bacterial DNA gyrase and topoisomerase IV, thereby blocking DNA replication in susceptible bacteria. It exhibits potent antibacterial activity against Gram-negative bacteria, acting as a bacteriostatic agent at lower concentrations and as a bactericidal agent at higher concentrations. This product is supplied as a 1% ready-to-use solution and is commonly used as a selective medium additive in microbiology to suppress the growth of non-target bacterial populations. It is widely applicable in bacteriological research and microbiological detection applications.