计算溶液所需的质量、体积或浓度。
,适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
ND-336 is a selective inhibitor of matrix metalloproteinase (MMP)-2 , MMP-9 , and MMP-14 , with K i s of 85, 150, and 120 nM, respectively. ND-336 accelerates diabetic wound healing in mice by lowering inflammation and by enhancing angiogenesis and re-epithelialization of the wound
In Vivo
ND-336 accelerates diabetic wound healing by decreasing inflammation and by enhancing angiogenesis and re-epithelialization of the wound, thus reversing the pathological condition . ND-336 (0.05-0.01 mg; topical application; daily for 14 day) accelerates diabetic wound healing . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Female diabetic db/db mice Dosage: 0.05, 0.025, and 0.01 mg Administration: Topical application; daily for 14 day Result: Healed 1.2- to 1.6-fold faster than those treated with ND-322 than those treated with vehicle.
Form:Solid
IC50& Target:MMP-2 85 nM (Ki) MMP-9 150 nM (Ki) MMP-14 120 nM (Ki)