3-OH-Kynurenamine dihydroiodide is the dihydroiodide form of 3-OH-Kynurenamine. 3-OH-Kynurenamine dihydroiodide is an activator for aryl hydrocarbon receptor ( AhR ), and thus regulates the immune response. 3-OH-Kynurenamine dihydroiodide upregulates the expressions of Ido1 and Tgfb1, ameliorates the skin inflammation in psoriasis mouse model and kidney damage in nephrotoxic lupus mouse model.