计算溶液所需的质量、体积或浓度。
Org41841
有货
概述
Org41841 is a partial agonist of both luteinizing hormone/chorionic gonadotropin receptor ( LHCGR ) and thyroid-stimulating hormone receptor ( TSHR ) with EC 50 s of 0.2 and 7.7 μM, respectively.
In Vitro
Functional assays demonstrate that Org41841 is a partial agonist of both luteinizing hormone/chorionic gonadotropin receptor (LHCGR) and thyroid-stimulating hormone receptor (TSHR) with EC 50 s of 0.2 and 7.7 μM, respectively. Treatment of L570F with Org41841 reveals an improved EC 50 of 800 nM. M9 responds to Org41841 with an improved EC 50 of 2700 nM and a greatly improved efficacy for signaling to 99% of the maximal value observed for thyroid-stimulating hormone (TSH) stimulation of thyroid-stimulating hormone receptor (TSHR). MCE has not independently confirmed the accuracy of these methods. They are for reference only.
IC50& Target:EC50: 0.2 μM (LHCGR), 7.7 μM (TSHR)
规格
别名
组织41841
规格或纯度
Moligand™,10mM in DMSO
英文名称
Org41841
生化机理
Org41841 是促黄体生成素/绒毛膜促性腺激素受体（LHCGR）和促甲状腺激素受体（TSHR）的部分激动剂，其 EC 50 s 分别为 0.2 和 7.7 μM。
储存条件
-80℃储存
运输条件
特低温运输
作用类型
激动剂
名称和识别符
分子类型
小分子
Isomeric SMILES
CC(C)(C)NC(=O)C1=C(C2=C(N=C(N=C2S1)SC)C3=CC(=CC=C3)OC)N
关联CAS
PubChem CID
MeSH Entry Terms
Org 41841;Org-41841;Org41841
分子量
402.53
高级数据
安全和危险性（GHS）
质检证书(CoA,COO,BSE/TSE 和分析图谱)
C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:
溶液计算器
产品仅提供给经过验证的企业、机构和合格的专业人员用于研发。不适用于人类、动物、诊断或治疗。
Copyright © 2023至今 上海阿拉丁生化科技股份有限公司 SSE:688179 保留所有权利。
危险品化学品经营许可证（带存储）