计算溶液所需的质量、体积或浓度。
为什么选择此级别
，适用于对基线干扰要求严格的色谱和分析工作流程。
储存与运输
干燥,-80℃储存。特低温运输 。请查阅批次 COA 获取详细规格。
质量文档
SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。
文献证明
在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
概述
Omadacycline (PTK 0796) hydrochloride, a first-in-class orally active aminomethylcycline antibacterial , is a member of the tetracycline class of antibiotics . Omadacycline hydrochloride acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline hydrochloride possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline hydrochloride can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections
In Vitro
Omadacycline displays activity against methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus (VRE), beta-hemolytic streptococci, penicillin-resistant Streptococcus pneumonia (PRSP) and Haemophilus influenzae (H. influenzae) , with MIC 90 s of 1.0, 0.25, 0.5, 0.25 and 2.0 μg/mL respectively. Omadacycline is active against strains expressing tetracycline and other antibiotics resistance by ribosomal protection and active tetracycline efflux. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
Omadacycline (0.11-18 mg/kg; a single i.v.) exhibits efficacy against Streptococcus pneumonia , Escherichia coli , and Staphylococcus aureus in mice systemic infection model, with ED 50 s ranging from 0.30 mg/kg to 3.39 mg/kg. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
IC50& Target:Tetracycline
规格
别名
盐酸奥玛环素
规格或纯度
10mM in DMSO
英文名称
Omadacycline hydrochloride
生化机理
盐酸奥马他环素（PTK 0796）是第一类口服活性氨甲基环素抗菌药，属于四环素类抗生素。盐酸奥美拉唑霉素通过与细菌的蛋白质结合，抑制细菌蛋白质的合成。
储存条件
干燥,-80℃储存
运输条件
特低温运输
作用类型
抑制剂
名称和识别符
分子类型
小分子
Isomeric SMILES
CC(C)(C)CNCC1=CC(=C2C[C@H]3C[C@H]4[C@@H](C(=O)C(=C([C@]4(C(=O)C3=C(C2=C1O)O)O)O)C(=O)N)N(C)C)N(C)C.Cl
PubChem CID
分子量
593.11
技术文档
高级数据
质检证书（CoA,COO,BSE/TSE 和分析图谱)
C of A & Other Certificates(BSE/TSE, COO):
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溶液计算器
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