基本描述

别名	4-硝基苯基磷酸盐二钠盐六水合物 \| pNPP 二钠六水合物 \| 磷酸4-硝基苯酯二钠盐六水合物 \| 4-硝基苯基磷酸二钠六水合物 \| 磷酸4-硝基苯酯二钠盐六水合物 \| pNPP二钠盐六水合物
英文别名	PNPP \| 4-Nitrophenyl phosphate disodium salt hexahydrate \| p-nitrophenyl phosphate disodium salt hexahydrate \| 4-Nitrophenyl phosphate, disodium salt hexahydrate \| SY074980 \| 4-Nitrophenyl phosphate disodium salt hexahydrate (PNPP) \| Phosphatase \| FT-0766
规格或纯度	≥98%
英文名称	4-Nitrophenyl phosphate disodium salt hexahydrate
生化机理	酸性和碱性磷酸酶的发色底物。反应产生黄色的可溶性最终产物。可用3 N NaOH终止反应，并在405 nm处读数。可用于执行动力学和终点测定。
应用	测定酸性和碱性磷酸酶（phosphatases）的显色底物；反应能产生黄色的末端产物，在波长405nm可以读取，该反应能被3 N NaOH溶液终止。
储存温度	-20°C储存
运输条件	超低温冰袋运输
备注	如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。
产品介绍	测定酸性和碱性磷酸酶（phosphatases）的显色底物；反应能产生黄色的末端产物，在波长405nm可以读取，该反应能被3 N NaOH溶液终止。 Chromogenic substrate for the determination of acid and alkaline phosphatases. The reaction produces a soluble end product that is yellow in color. The reaction may be stopped with 3 N NaOH and read at 405 nm.

AI解读

名称和识别符

PubChem SID	504760800
EC号	224-246-5
IUPAC Name	disodium;(4-nitrophenyl) phosphate;hexahydrate
INCHI	InChI=1S/C6H6NO6P.2Na.6H2O/c8-7(9)5-1-3-6(4-2-5)13-14(10,11)12;;;;;;;;/h1-4H,(H2,10,11,12);;;61H2/q;2+1;;;;;;/p-2
InChi Key	KAKKHKRHCKCAGH-UHFFFAOYSA-L
Canonical SMILES	C1=CC(=CC=C1[N+](=O)[O-])OP(=O)([O-])[O-].O.O.O.O.O.O.[Na+].[Na+]
Isomeric SMILES	C1=CC(=CC=C1[N+](=O)[O-])OP(=O)([O-])[O-].O.O.O.O.O.O.[Na+].[Na+]
WGK Germany	3
关联CAS	4264-83-9
PubChem CID	2723710
分子量	371.14
Beilstein号	6237
Reaxy-Rn	5324661

化学和物理性质

溶解性	Miscible with water. Immiscible with ethanol and acetone.
密度	1.712
敏感性	对热和光线敏感
熔点	300°C
分子量	371.140 g/mol
XLogP3
氢键供体数Hydrogen Bond Donor Count	6
氢键受体数Hydrogen Bond Acceptor Count	12
可旋转键计数Rotatable Bond Count	1
精确质量Exact Mass	371.021 Da
单同位素质量Monoisotopic Mass	371.021 Da
拓扑极表面积Topological Polar Surface Area	124.000 Å²
重原子数Heavy Atom Count	22
形式电荷Formal Charge	0
复杂度Complexity	238.000
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	0
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	9

安全和危险性（GHS）

象形图	GHS08
信号词	Danger
危险声明	H334: 吸入可能引起过敏或哮喘病症状或呼吸困难
预防措施声明	P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P501: 将内容物/容器处理到。。。 P284: 如果通风不良，请佩戴呼吸防护装置。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P342+P316: 如果出现呼吸道症状：立即寻求急救。
WGK Germany	3
Reaxy-Rn	5324661

质检证书（CoA,COO,BSE/TSE 和分析图谱)

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找到10个结果

批号(Lot Number)	证书类型	日期	货号
L2416853	分析证书	24-12-23	P109039
L2416854	分析证书	24-12-23	P109039
L2416874	分析证书	24-12-23	P109039
G2030048	分析证书	24-05-08	P109039
F2420292	分析证书	24-02-22	P109039
F2420293	分析证书	24-02-22	P109039
F2420294	分析证书	24-02-22	P109039
I2220656	分析证书	22-06-17	P109039
I2220701	分析证书	22-06-17	P109039
K2310010	分析证书	22-06-17	P109039

此产品的引用文献

如何在您的发表作品中引用阿拉丁的产品和网站?

1. Yan Li, Mingjie Chen, Huiming Liu, Dandan Zhang, Qing-Shan Shi, Xiao-Bao Xie, Yanzhu Guo. (2023) Antimicrobial Peptide-Inspired Design of Amino-Modified Lignin with Improved Antimicrobial Activities. BIOMACROMOLECULES, 24 (11): (5381–5393). [PMID:37908117] [10.1021/acs.biomac.3c00841]
2. Shijie Cao, Leyao Li, Hongwei An, Guobin Mao, Junbiao Dai, Yingxin Ma. (2023) Development of dual-mode ELISA based on ALP-catalyzed APP hydrolysis for IL-6 detection. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 236 (5): (115754). [PMID:37783051] [10.1016/j.jpba.2023.115754]
3. Shiyi Chen, Feiyang Tian, Juan Peng, Yan Meng, Yu Wang, Xiaogang He, Qian Wang, Ganghui Chu. (2023) Turning Zr(IV) into a phosphate ester mimetic enzyme via de novo synthesis for hydrolyzing organophosphorus warfare agents and rapid activity prediction by near-infrared spectroscopy. MICROCHEMICAL JOURNAL, 195 (109379). [PMID:8318735] [10.1016/j.microc.2023.109379]
4. Guobin Mao, Chunmin Qiu, Xing Luo, Yingqi Liang, Liqing Zhao, Weiren Huang, Junbiao Dai, Yingxin Ma. (2023) Synergistic effect-triggered fluorescence quenching enables rapid and sensitive detection of alkaline phosphatase. ANALYTICA CHIMICA ACTA, 1272 (341510). [PMID:37355336] [10.1016/j.aca.2023.341510]
5. Yuanhua Zhang, Yan Qiu, Lan Xia, Long Yuan, Hailong Wu, Rui Shi, Anqi Chen, Kai Zhou, Mingxue Zhou, Kailian Zhang, Chunxiang Zhang, Zhining Xia, Qifeng Fu. (2023) Surface Patterning Enhanced Visualization for Ultrasensitive Naked-Eye Detection and RGB-Based High-Density Information Storage. Advanced Optical Materials, 11 (14): (2300010). [10.1002/adom.202300010]
6. Luyu Wei, Fu Jiao, Zhilong Wang, Long Wu, Daming Dong, Yiping Chen. (2022) Enzyme-modulated photothermal immunoassay of chloramphenicol residues in milk and egg using a self-calibrated thermal imager. FOOD CHEMISTRY, 392 (133232). [PMID:35636182] [10.1016/j.foodchem.2022.133232]
7. LI Ying, YANG Dan, CHEN Bo, CAO Hai-Yan, ZHANG Qing-Feng. (2021) Antioxidative and digestive enzymes inhibitory activities of 27 edible plants. Food Science and Technology, 42 (e88621). [10.1590/fst.88621]
8. Honghong Rao, Huiyi Huang, Xinyuan Zhang, Xin Xue, Mingyue Luo, Haixia Liu, Zhonghua Xue. (2020) A simple thermometer-based photothermometric assay for alkaline phosphatase activity based on target-induced nanoprobe generation. NEW JOURNAL OF CHEMISTRY, 44 (41): (17753-17760). [10.1039/D0NJ03920A]
9. Mingyue Luo, Xin Xue, Honghong Rao, Hongqiang Wang, Xiuhui Liu, Xibin Zhou, Zhonghua Xue, Xiaoquan Lu. (2020) Simply converting color signal readout into thermal signal readout for breaking the color resolution limitation of colorimetric sensor. SENSORS AND ACTUATORS B-CHEMICAL, 309 (127707). [10.1016/j.snb.2020.127707]
10. Pengjuan Ni, Chuanxia Chen, Yuanyuan Jiang, Chenghui Zhang, Bo Wang, Yizhong Lu, Hua Wang. (2020) A fluorescent assay for alkaline phosphatase activity based on inner filter effect by in-situ formation of fluorescent azamonardine. SENSORS AND ACTUATORS B-CHEMICAL, 302 (127145). [10.1016/j.snb.2019.127145]
11. Yunlei Zhou, Fei Li, Hanwen Wu, Yan Chen, Huanshun Yin, Shiyun Ai, Jun Wang. (2019) Electrochemical aptasensing strategy for kanamycin detection based on target-triggered single-strand DNA adsorption on MoS2 nanosheets and enzymatic signal amplification. SENSORS AND ACTUATORS B-CHEMICAL, 296 (126664). [10.1016/j.snb.2019.126664]
12. Yaping Zhong, Fengfeng Xue, Peng Wei, Ruohan Li, Chunyan Cao, Tao Yi. (2018) Water-soluble MoS2 quantum dots for facile and sensitive fluorescence sensing of alkaline phosphatase activity in serum and live cells based on the inner filter effect. Nanoscale, 10 (45): (21298-21306). [PMID:30422141] [10.1039/C8NR05549A]
13. Dong He, Wen Luo, Zhiyuan Wang, Pengmei Lv, Zhenhong Yuan, Shaowei Huang, Jingliang Xv. (2017) Establishment and application of a modified membrane-blot assay for Rhizomucor miehei lipases aimed at improving their methanol tolerance and thermostability. ENZYME AND MICROBIAL TECHNOLOGY, 102 (35). [PMID:28465058] [10.1016/j.enzmictec.2017.03.010]
14. Haijian Liu, Ming Li, Yining Xia, Xueqin Ren. (2017) A Turn-On Fluorescent Sensor for Selective and Sensitive Detection of Alkaline Phosphatase Activity with Gold Nanoclusters Based on Inner Filter Effect. ACS Applied Materials & Interfaces, 9 (1): (120–126). [PMID:27966342] [10.1021/acsami.6b11920]
15. J. B. Fan, S. van de Velde, W. B. Sun, H. Yu, Y. L. Zhang, D. Wang. (2016) Enhanced toxicity of Cry2Ab with cantharidin and its analogues on Mythimna separata. JOURNAL OF APPLIED ENTOMOLOGY, 141 (5): (363-371). [10.1111/jen.12359]
16. Qingming Zhang, Xue Li, Bingchen Li, Huanshun Yin, Shiyun Ai. (2015) An electrochemical biosensor for the activity assay of polynucleotide kinase and inhibitor screening. Analytical Methods, 7 (23): (9984-9991). [10.1039/C5AY02295A]
17. Yunlei Zhou, Zhiqing Yang, Xue Li, Yue Wang, Huanshun Yin, Shiyun Ai. (2015) Electrochemical biosensor for detection of DNA hydroxymethylation based on glycosylation and alkaline phosphatase catalytic signal amplification. ELECTROCHIMICA ACTA, 174 (647). [10.1016/j.electacta.2015.06.043]
18. Mo Wang, Bingchen Li, Qing Zhou, Huanshun Yin, Yunlei Zhou, Shiyun Ai. (2015) Label-free, Ultrasensitive and Electrochemical Immunosensing Platform for microRNA Detection Using Anti-DNA:RNA Hybrid Antibody and Enzymatic Signal Amplification. ELECTROCHIMICA ACTA, 165 (130). [10.1016/j.electacta.2015.03.011]
19. Zhi-Gang Wang, Ji-Lin Zhang, De-Hui Sun, Jia-Zuan Ni. (2014) Novel Ti4+-chelated magnetic nanostructured affinity microspheres containing N-methylene phosphonic chitosan for highly selective enrichment and rapid separation of phosphopeptides. Journal of Materials Chemistry B, 2 (39): (6886-6892). [PMID:32261885] [10.1039/C4TB00916A]

参考文献

1. Yan Li, Mingjie Chen, Huiming Liu, Dandan Zhang, Qing-Shan Shi, Xiao-Bao Xie, Yanzhu Guo. (2023) Antimicrobial Peptide-Inspired Design of Amino-Modified Lignin with Improved Antimicrobial Activities. BIOMACROMOLECULES, 24 (11): (5381–5393). [PMID:37908117] [10.1021/acs.biomac.3c00841]
2. Shijie Cao, Leyao Li, Hongwei An, Guobin Mao, Junbiao Dai, Yingxin Ma. (2023) Development of dual-mode ELISA based on ALP-catalyzed APP hydrolysis for IL-6 detection. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 236 (5): (115754). [PMID:37783051] [10.1016/j.jpba.2023.115754]
3. Shiyi Chen, Feiyang Tian, Juan Peng, Yan Meng, Yu Wang, Xiaogang He, Qian Wang, Ganghui Chu. (2023) Turning Zr(IV) into a phosphate ester mimetic enzyme via de novo synthesis for hydrolyzing organophosphorus warfare agents and rapid activity prediction by near-infrared spectroscopy. MICROCHEMICAL JOURNAL, 195 (109379). [PMID:8318735] [10.1016/j.microc.2023.109379]
4. Guobin Mao, Chunmin Qiu, Xing Luo, Yingqi Liang, Liqing Zhao, Weiren Huang, Junbiao Dai, Yingxin Ma. (2023) Synergistic effect-triggered fluorescence quenching enables rapid and sensitive detection of alkaline phosphatase. ANALYTICA CHIMICA ACTA, 1272 (341510). [PMID:37355336] [10.1016/j.aca.2023.341510]
5. Yuanhua Zhang, Yan Qiu, Lan Xia, Long Yuan, Hailong Wu, Rui Shi, Anqi Chen, Kai Zhou, Mingxue Zhou, Kailian Zhang, Chunxiang Zhang, Zhining Xia, Qifeng Fu. (2023) Surface Patterning Enhanced Visualization for Ultrasensitive Naked-Eye Detection and RGB-Based High-Density Information Storage. Advanced Optical Materials, 11 (14): (2300010). [10.1002/adom.202300010]
6. Luyu Wei, Fu Jiao, Zhilong Wang, Long Wu, Daming Dong, Yiping Chen. (2022) Enzyme-modulated photothermal immunoassay of chloramphenicol residues in milk and egg using a self-calibrated thermal imager. FOOD CHEMISTRY, 392 (133232). [PMID:35636182] [10.1016/j.foodchem.2022.133232]
7. LI Ying, YANG Dan, CHEN Bo, CAO Hai-Yan, ZHANG Qing-Feng. (2021) Antioxidative and digestive enzymes inhibitory activities of 27 edible plants. Food Science and Technology, 42 (e88621). [10.1590/fst.88621]
8. Honghong Rao, Huiyi Huang, Xinyuan Zhang, Xin Xue, Mingyue Luo, Haixia Liu, Zhonghua Xue. (2020) A simple thermometer-based photothermometric assay for alkaline phosphatase activity based on target-induced nanoprobe generation. NEW JOURNAL OF CHEMISTRY, 44 (41): (17753-17760). [10.1039/D0NJ03920A]
9. Mingyue Luo, Xin Xue, Honghong Rao, Hongqiang Wang, Xiuhui Liu, Xibin Zhou, Zhonghua Xue, Xiaoquan Lu. (2020) Simply converting color signal readout into thermal signal readout for breaking the color resolution limitation of colorimetric sensor. SENSORS AND ACTUATORS B-CHEMICAL, 309 (127707). [10.1016/j.snb.2020.127707]
10. Pengjuan Ni, Chuanxia Chen, Yuanyuan Jiang, Chenghui Zhang, Bo Wang, Yizhong Lu, Hua Wang. (2020) A fluorescent assay for alkaline phosphatase activity based on inner filter effect by in-situ formation of fluorescent azamonardine. SENSORS AND ACTUATORS B-CHEMICAL, 302 (127145). [10.1016/j.snb.2019.127145]
11. Yunlei Zhou, Fei Li, Hanwen Wu, Yan Chen, Huanshun Yin, Shiyun Ai, Jun Wang. (2019) Electrochemical aptasensing strategy for kanamycin detection based on target-triggered single-strand DNA adsorption on MoS2 nanosheets and enzymatic signal amplification. SENSORS AND ACTUATORS B-CHEMICAL, 296 (126664). [10.1016/j.snb.2019.126664]
12. Yaping Zhong, Fengfeng Xue, Peng Wei, Ruohan Li, Chunyan Cao, Tao Yi. (2018) Water-soluble MoS2 quantum dots for facile and sensitive fluorescence sensing of alkaline phosphatase activity in serum and live cells based on the inner filter effect. Nanoscale, 10 (45): (21298-21306). [PMID:30422141] [10.1039/C8NR05549A]
13. Dong He, Wen Luo, Zhiyuan Wang, Pengmei Lv, Zhenhong Yuan, Shaowei Huang, Jingliang Xv. (2017) Establishment and application of a modified membrane-blot assay for Rhizomucor miehei lipases aimed at improving their methanol tolerance and thermostability. ENZYME AND MICROBIAL TECHNOLOGY, 102 (35). [PMID:28465058] [10.1016/j.enzmictec.2017.03.010]
14. Haijian Liu, Ming Li, Yining Xia, Xueqin Ren. (2017) A Turn-On Fluorescent Sensor for Selective and Sensitive Detection of Alkaline Phosphatase Activity with Gold Nanoclusters Based on Inner Filter Effect. ACS Applied Materials & Interfaces, 9 (1): (120–126). [PMID:27966342] [10.1021/acsami.6b11920]
15. J. B. Fan, S. van de Velde, W. B. Sun, H. Yu, Y. L. Zhang, D. Wang. (2016) Enhanced toxicity of Cry2Ab with cantharidin and its analogues on Mythimna separata. JOURNAL OF APPLIED ENTOMOLOGY, 141 (5): (363-371). [10.1111/jen.12359]
16. Qingming Zhang, Xue Li, Bingchen Li, Huanshun Yin, Shiyun Ai. (2015) An electrochemical biosensor for the activity assay of polynucleotide kinase and inhibitor screening. Analytical Methods, 7 (23): (9984-9991). [10.1039/C5AY02295A]
17. Yunlei Zhou, Zhiqing Yang, Xue Li, Yue Wang, Huanshun Yin, Shiyun Ai. (2015) Electrochemical biosensor for detection of DNA hydroxymethylation based on glycosylation and alkaline phosphatase catalytic signal amplification. ELECTROCHIMICA ACTA, 174 (647). [10.1016/j.electacta.2015.06.043]
18. Mo Wang, Bingchen Li, Qing Zhou, Huanshun Yin, Yunlei Zhou, Shiyun Ai. (2015) Label-free, Ultrasensitive and Electrochemical Immunosensing Platform for microRNA Detection Using Anti-DNA:RNA Hybrid Antibody and Enzymatic Signal Amplification. ELECTROCHIMICA ACTA, 165 (130). [10.1016/j.electacta.2015.03.011]
19. Zhi-Gang Wang, Ji-Lin Zhang, De-Hui Sun, Jia-Zuan Ni. (2014) Novel Ti4+-chelated magnetic nanostructured affinity microspheres containing N-methylene phosphonic chitosan for highly selective enrichment and rapid separation of phosphopeptides. Journal of Materials Chemistry B, 2 (39): (6886-6892). [PMID:32261885] [10.1039/C4TB00916A]

溶液计算器

摩尔浓度计算器

计算溶液所需的质量、体积或浓度。

质量

=

浓度

x

体积

x

分子量

g/mol

稀释计算器

计算配制储备溶液所需的稀释度。

浓度1（C1）

x

体积 1 (V1)

=

浓度 2 (C2)

x

体积 2 (V2)

复溶计算器

复溶计算器允许您快速计算试剂的体积，以复溶小瓶。只需输入试剂的质量和目标浓度，计算器将确定其余部分。

体积（添加到小瓶中）

=

质量（小瓶）

÷

所需的复溶浓度

货号 (SKU)	包装规格	是否现货
P109039-1g	1g	现货
P109039-5g	5g	现货
P109039-25g	25g	现货
P109039-100g	100g	现货

对硝基苯磷酸二钠六水合物(PNPP)

库存信息

库存信息

库存信息

库存信息

基本描述

AI解读

名称和识别符

化学和物理性质

安全和危险性（GHS）

质检证书（CoA,COO,BSE/TSE 和分析图谱)

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此产品的引用文献

参考文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器

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