PROTAC TBL1X degrader-1 (Compound TD11) is a PROTAC degrader for Transducin β-like protein 1 X-linked ( TBL1X ), and exhibits cytotoxicity in lymphoma cell Riva, Pfeiffer and Granta-519 with IC 50 of 0.795, 0.397 and 0.522 μM, respectively. (Pink: ligand for target protein: TBL1X ligand 1 ; Black: linker ; Blue: ligand for E3 ligase: Thalidomide 4-fluoride )