PTK7/β-catenin-IN-2 (compound 04967) is an inhibitor of PTK7 / β-catenin. It inhibits the binding of PTK7 to β-catenin (IC 50 : 5.6 μM), thereby inhibiting the signaling of the Wnt/β-catenin pathway. PTK7/β-catenin-IN-2 targets cell growth dependent on the Wnt signaling pathway and has anticancer properties. PTK7/β-catenin-IN-2 also showed inhibitory potency against p53 and MDM2 binding with an IC 50 of 157.1 μM.