PROTAC AR Degrader-6 (Compound 1) is a PROTAC androgen receptor degrader (DC 50 : 10 nM in VCaP cell). PROTAC AR Degrader-6 blocks the process of androgen receptor transduction and also degrades the receptor itself. PROTAC AR Degrader-6 can be used for prostate cancer research. Pink: AR ligand ; Blue: E3 ligase ligand ; Black: linker.