A2620101计算溶液所需的质量、体积或浓度。
为什么选择此级别
提供 ≥90% 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。
储存与运输
-20°C储存。超低温运输 。请查阅批次 COA 获取详细规格。
质量文档
SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。
文献证明
在色谱分析、有机合成和交叉偶联反应领域已被 2 篇同行评审文献引用。
概述
Information
Phytosterols, also called plant sterols or stanol esters, are specialized compounds found in plants that are structurally similar to cholesterol found in humans.
In vitro
Plant sterols or phytosterols are structurally similar to cholesterol and exist in several forms in plants, including β-sitosterol, campesterol, stigmasterol and cycloartenol. Phytosterols can protect cells from damage by reactive oxygen species. Phytosterols can promote cell apoptosis. The incorporation of phytosterols into lipid rafts, altering their structure, may result in beneficial changes in signal transduction.
In vivo
Phytosterol and stanol (or phytosterols) consumption reduces intestinal cholesterol absorption, leading to decreased blood LDL-cholesterol levels and lowered cardiovascular disease risk. Recent studies suggest that phytosterols inhibit the production of carcinogens, cancer-cell growth, invasion and metastasis, and promote apoptosis of cancerous cells. Phytosterols occur naturally in plants either esterified with fatty acids in the cell membranes or in free form within the cells. After ingestion, phytosterols are emulsified by bile salts secreted into the small intestine to form micelles for digestion. After micelle formation, the esterified phytosterols are hydrolyzed to free phytosterols probably by cholesterol esterase and pancreatic lipase enzymes. Free phytosterols are then absorbed into enterocytes. In the enterocytes, these compounds become esterified to fatty acids by acyl-CoA cholesterol acyltransferases, and combined with cholesterol, triacylglycerol and apolipoproteins to form chylomicrons. The chylomicrons are secreted into the lymph and then transferred to the bloodstream, where they are transformed to chylomicron remnants after the uptake of triacylglycerol by cells and transported to the liver. In the liver, the phytosterols may either be used for synthesis of bile salts or be incorporated into very low-density lipoproteins and be secreted into the blood, from where they are converted to low-density lipoproteins and presented to cells for uptake. In the tissues, phytosterols are incorporated into the cell membranes and have been found to be highly concentrated in the lungs, adrenal cortex, intestinal epithelia and ovaries.
规格
规格或纯度
≥90%
英文名称
Phytosterols
生化机理
植物甾醇又称植物固醇或甾醇酯，是植物中发现的特殊化合物，在结构上与人类体内的胆固醇相似。
储存条件
-20°C储存
运输条件
超低温运输
纯度
≥90%
名称和识别符
EC号
619-079-3
分子类型
小分子
IUPAC Name
(3S,8S,9S,10R,13R,17R)-17-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
INCHI
1S/C29H50O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h10,19-21,23-27,30H,7-9,11-18H2,1-6H3/t20-,21-,23+,24+,25-,26?,27+,28+,29-/m1/s1
InChi Key
KZJWDPNRJALLNS-ICLVQLPZSA-N
Smiles
CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C
Isomeric SMILES
CC[C@H](CC[C@@H](C)[C@H]1CCC2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C)C(C)C
技术文档
高级数据
三维结构
交互式化学结构模型
化学和物理性质
溶解性
Solubility (25°C) In vitro DMSO: Insoluble; Water: Insoluble; Ethanol: Insoluble;
敏感性
对湿度敏感
质检证书（CoA,COO,BSE/TSE 和分析图谱)
此产品的引用文献
溶液计算器
常见问题
本产品的纯度是多少？
本产品的化学纯度（含量）为 ≥90%。批次的具体数值以分析证书（COA）为准。
本产品应如何储存？
请于?20 °C条件下保存。需冷冻保存以维持规定的有效期。
本产品如何运输？
本产品采用保温箱配冰袋运输。收货后请立即拆包，并按上述储存条件保存。
本产品的 CAS 号、分子式和分子量是多少？
本产品的 CAS 号为 949109-75-5。InChIKey KZJWDPNRJALLNS-ICLVQLPZSA-N。
如何获取批次专用COA？
每个订单都会随附分析证书（COA），您也可以从账户订单历史中下载。如需订购前的COA，请联系您的客户代表，或使用PDP上的"申请COA"按钮——我们将提供代表性批次的COA。
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