Aldeyde PEG is an amine reactive PEG derivative that can be used to modify biomolecules via available amine groups. The reaction between aldehyde group with ε-amine of lysine residues and the α-amine at the N-terminus produces an intermediate Schiff base. Further reduction with hydride will form a stable C-N bond. PEG aldehydes react with amine groups at a pH of from 5.5 to 9.5. Higher pH will result in multiple Pegylation with both terminal and lysine groups. Aldehyde PEG is a commonly used PEG reagent for n-terminus pegylation in proteins or peptides.
规格
规格或纯度
MW 10000 Da
英文名称
PEG Aldehyde, mPEG-CH2CHO
储存条件
-20°C储存,充氩
运输条件
超低温运输
名称和识别符
分子类型
聚合物
高级数据
化学和物理性质
溶解性
Soluble in regular aqeous solution as well as most organic solvents