盐酸巴马汀

小ber碱生物碱

有货

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货号 (SKU)	包装规格	是否现货	价格	数量
P408401-1ml	1ml	现货

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Compound libraries (12332)

基本描述

英文别名	2,3,9,10-Tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium chloride
规格或纯度	10mM in DMSO
英文名称	Palmatine chloride
生化机理	盐酸巴马汀（氯化巴马汀（6CI,7CI）；Fibrauretin）是巴马汀的盐酸盐，而巴马汀是一种原小檗碱。
储存温度	-80℃储存
运输条件	超低温冰袋运输
产品介绍	Palmatine chloride 是一种不可逆的 IDO-1 抑制剂，对 HEK 293-hIDO-1 和 rhIDO-1 的 IC50 分别为 3 μM 和 157 μM。Palmatine chloride 也能非竞争性抑制西尼罗病毒 (WNV) NS2B-NS3 蛋白酶，IC50 为 96 μM。Palmatine chloride 具有抗癌、抗炎、神经保护、抗细菌、抗病毒活性。 Information Palmatine hydrochloride (Palmatine chloride (6CI,7CI); Fibrauretin) is a hydrochloride salt of palmatine which is a protoberberine alkaloid. In vitro In vivo Cell Data cell lines： Concentrations： Incubation Time： Powder Purity:≥97%

CYP3A4 Tclin 细胞色素P450 3A4(Cytochrome P450 3A4) (1 活性数据)

点击查看靶蛋白信息： CYP3A4

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

分子类型	小分子
Canonical SMILES	[Cl-].COC1=CC=C2C=C3C4=C(CC[N+]3=CC2=C1OC)C=C(OC)C(=C4)OC
分子量	387.86

Concentration(Compounding value)	9.0-11.0(mmol/L)
Appearance(yellow liquid)	Pass
Record the entire process by video	Conform

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

1. Xinchi Feng, Kun Wang, Xintong Hu, Liwei Chai, Shijie Cao, Liqin Ding, Feng Qiu. (2020) Systematic screening and characterization of absorbed constituents and in vivo metabolites in rats after oral administration of Rhizoma coptidis using UPLC-Q-TOF/MS. BIOMEDICAL CHROMATOGRAPHY, 34 (10): (e4919). [PMID:32533560] [10.1002/bmc.4919]
2. Wenpeng Zhang, Zilin Chen. (2013) Preparation of micropipette tip-based molecularly imprinted monolith for selective micro-solid phase extraction of berberine in plasma and urine samples. TALANTA, 103 (103). [PMID:23200364] [10.1016/j.talanta.2012.10.014]

1. Xinchi Feng, Kun Wang, Xintong Hu, Liwei Chai, Shijie Cao, Liqin Ding, Feng Qiu. (2020) Systematic screening and characterization of absorbed constituents and in vivo metabolites in rats after oral administration of Rhizoma coptidis using UPLC-Q-TOF/MS. BIOMEDICAL CHROMATOGRAPHY, 34 (10): (e4919). [PMID:32533560] [10.1002/bmc.4919]
2. Wenpeng Zhang, Zilin Chen. (2013) Preparation of micropipette tip-based molecularly imprinted monolith for selective micro-solid phase extraction of berberine in plasma and urine samples. TALANTA, 103 (103). [PMID:23200364] [10.1016/j.talanta.2012.10.014]