(Rac)-LY341495 is the isomer of LY341495 , and can be used as an experimental control. LY341495 is a metabotropic glutamate receptor ( mGluR ) antagonist with IC 50 s of 21 nM,14 nM, 7.8 μM, 8.2 μM, 170 nM, 990 nM, 22 μM for mGlu2, mGlu3, mGlu1a, mGlu5a, mGlu8, mGlu7, and mGlu4 receptors, respectively.