(Rac)-Rotigotine hydrochloride is a racemate of Rotigotine. Rotigotine is a full agonist of? dopamine receptor , a partial agonist of the? 5-HT1A receptor , and an antagonist of the? α2B-adrenergic receptor , with? K i s of 0.71?nM, 4-15?nM, and 83?nM for the dopamine D3 receptor and D2, D5, D4 receptors, and dopamine D1 receptor.