| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| rp150150-10μg |
10μg |
现货  |
| |
| rp150150-50μg |
50μg |
现货 |
| |
| rp150150-100μg |
100μg |
现货 |
| |
| rp150150-1mg |
1mg |
期货 |
|
| 产品名称 | Recombinant Human PGLYRP1/PGRP-S Protein |
|---|---|
| 别名 | 重组人PGLYRP1/PGRP-S蛋白 | 重组人肽聚糖识别蛋白1蛋白 |
| 英文别名 | Peptidoglycan recognition protein short | PGRP-S | peptidoglycan recognition protein 1 | Peptidoglycan recognition protein short | PGLYRP | PGLYRP1 | PGRP | peptidoglycan recognition protein | PGRPS | PGRP-S | MGC126894 | MGC126896 | TAG7 | TNF superfamil |
| 规格或纯度 | 生物活性, 无动物源, Carrier Free, ActiBioPure™, ≥95%(SDS-PAGE) |
| 产品介绍 |
Function |
| 生物活性 | Measured by its binding ability in a functional ELISA. When peptidoglycan is coated at 1 µg/mL (100 µL/well), the concentration of Recombinant Human PGLYRP1/PGRP-S that produces 50% optimal binding response is 0.75-4.5 ng/mL. |
| 内毒素水平 | <0.1 EU/μg |
| 表达系统 | HEK293 |
| 种属 | Human |
| 氨基酸 | 22-196 aa |
| 序列 | QETEDPACCSPIVPRNEWKALASECAQHLSLPLRYVVVSHTAGSSCNTPASCQQQARNVQHYHMKTLGWCDVGYNFLIGEDGLVYEGRGWNFTGAHSGHLWNPMSIGISFMGNYMDRVPTPQAIRAAQGLLACGVAQGALRSNYVLKGHRDVQRTLSPGNQLYHLIQNWPHYRSPHHHHHH |
| 蛋白标签 | C-His |
| 无载体 | Yes |
| 无动物源 | Yes |
| Accession # | O75594 |
| 来源 | 重组表达 |
| 预测分子量 | 20 kDa |
| SDS-PAGE | 23-27 kDa under reducing conditions. |
Recombinant Human PGLYRP1/PGRP-S Protein (rp150150) - Protein Bioactivity
Measured by its binding ability in a functional ELISA. Immobilized peptidoglycan at 1.0 µg/mL can bind Recombinant Human PGLYRP1/PGRP-S Protein (rp150150) with the ED50 of 3.8 ng/mL.
| 物理形态 | 冻干(Lyophilized) |
|---|---|
| 储存缓冲液 | Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH7.4. |
| 复溶 | Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml. |
| 储存温度 | -20°C储存,避免反复冻融 |
| 运输条件 | 超低温冰袋运输 |
| 稳定性与储存 | 在 -20~-80℃ 下可保存 1 年以上。收货后建议分装。避免冷冻/解冻循环。 |
| 分子类型 | 蛋白质 |
通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！
| 批号(Lot Number) | 证书类型 | 日期 | 货号 |
|---|---|---|---|
 ZJ24F1215908 |
分析证书 | 24-12-26 | rp150150 |
| ZJ24F1215909 |
分析证书 | 24-12-26 | rp150150 |
| ZJ24F1215910 |
分析证书 | 24-12-26 | rp150150 |
| 1. Denis V Yashin,Olga K Ivanova,Natalia V Soshnikova,Anton A Sheludchenkov,Elena A Romanova,Elena A Dukhanina,Alexander G Tonevitsky,Nikolai V Gnuchev,Alexander G Gabibov,Georgii P Georgiev,Lidia P Sashchenko. (2015-07-18) Tag7 (PGLYRP1) in Complex with Hsp70 Induces Alternative Cytotoxic Processes in Tumor Cells via TNFR1 Receptor.. The Journal of biological chemistry, 290 ((35)): (21724-21731). [PMID:26183779] |
| 2. Kang, D D, Liu, G G, Lundström, A A, Gelius, E E and Steiner, H H.. (1998) A peptidoglycan recognition protein in innate immunity conserved from insects to humans.. Proceedings of the National Academy of Sciences of the United States of America, (18): [PMID:9707603] |
| 3. Liu, C C, Xu, Z Z, Gupta, D D and Dziarski, R R.. (2001) Peptidoglycan recognition proteins: a novel family of four human innate immunity pattern recognition molecules.. The Journal of biological chemistry, (14): [PMID:11461926] |
| 4. Guan, Rongjin R, Wang, Qian Q, Sundberg, Eric J EJ and Mariuzza, Roy A RA.. (2005) Crystal structure of human peptidoglycan recognition protein S (PGRP-S) at 1.70 A resolution.. Journal of molecular biology, (8): [PMID:15769462] |
| 5. Lu, Xiaofeng X and 6 more authors.. (2006) Peptidoglycan recognition proteins are a new class of human bactericidal proteins.. The Journal of biological chemistry, (3): [PMID:16354652] |
| 6. Yashin, Denis V DV and 10 more authors.. (2011) The heat shock-binding protein (HspBP1) protects cells against the cytotoxic action of the Tag7-Hsp70 complex.. The Journal of biological chemistry, (25): [PMID:21247889] |
| 7. Read, Christine B CB and 14 more authors.. (2015) Cutting Edge: identification of neutrophil PGLYRP1 as a ligand for TREM-1.. Journal of immunology (Baltimore, Md. : 1950), (15): [PMID:25595774] |
| 8. Dukhanina, E A EA and 7 more authors.. (2015) A new role for PGRP-S (Tag7) in immune defense: lymphocyte migration is induced by a chemoattractant complex of Tag7 with Mts1.. Cell cycle (Georgetown, Tex.), [PMID:26654597] |
| 9. Sharapova, Tatiana N TN and 5 more authors.. (2017) Innate Immunity Protein Tag7 Induces 3 Distinct Populations of Cytotoxic Cells That Use Different Mechanisms to Exhibit Their Antitumor Activity on Human Leukocyte Antigen-Deficient Cancer Cells.. Journal of innate immunity, [PMID:28977785] |
| 10. Sharapova, Tatiana N TN and 5 more authors.. (2017) Innate immunity protein Tag7 (PGRP-S) activates lymphocytes capable of Fasl-Fas-dependent contact killing of virus-infected cells.. IUBMB life, [PMID:29083508] |
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