SBN-284 (compound 3x) is a dual inhibitor of blood-brain permeable Cholinesterases and the NLRP3 inflammasome and is effective against EeAChE, hAChE and eqBChE, the IC 50 values of are 0.37, 0.31, 0.29 μM respectively, and the EC 50 of NLRP3 inflamm is 1 μM. SBN-284 can be used in Alzheimer's disease research.