计算溶液所需的质量、体积或浓度。
Sitravatinib malate (MGCD516 malate) is an orally bioavailable receptor tyrosine kinase (RTK) inhibitor with IC 50 s of 1.5 nM, 2 nM, 2 nM, 5 nM, 6 nM,6 nM, 8 nM, 0.5 nM, 29 nM, 5 nM, and 9 nM for Axl , MER , VEGFR3 , VEGFR2 , VEGFR1 , KIT, FLT3 , DDR2 , DDR1 , TRKA , TRKB , respectively. Sitravatinib malate shows potent single-agent antitumor efficacy and enhances the activity of PD-1 blockade through promoting an antitumor immune microenvironment.