Stafia-1 is a potent STAT5a inhibitor ( K i =10.9 μM, IC 50 =22.2 μM). Stafia-1 displays high selectivity over STAT5b and other STAT family members
In Vitro
Stafia-1 shows at least 9-fold selectivity over STAT5b and higher selectivity against other STAT family members. MCE has not independently confirmed the accuracy of these methods. They are for reference only.