Tubulin polymerization-IN-38 is an analogue of Tubulysin , a potent anticancer agent. Tubulin polymerization-IN-38 inhibits tubulin polymerization ( tubulin polymerisation ), thereby inducing apoptosis ( apoptosis ). Tubulysin series products are potent anti-microtubule toxins ( anti-microtubule toxins ) and can be used as ADC cytotoxins ( ADC Cytotoxin ) to synthesize ADCs.