计算溶液所需的质量、体积或浓度。
,适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
TW9 is a potent dual inhibitor simultaneously targeting BET and HDAC proteins with K D s of 0.069 μM, 0.231 μM for BRD4(1), BRD4(2), and an IC 50 of 0.29 μM for HDAC1 , respectively. TW9 is a newly generated adduct of the BET inhibitor (+)-JQ1 and class I HDAC inhibitor CI994. TW9 shows high potency in suppressing tumor growth in pancreatic ductal adenocarcinoma (PDAC). TW9 improves the efficacy of the chemotherapeutic agent Gemcitabine.