计算溶液所需的质量、体积或浓度。
TLR7 agonist 21 (Compound 27B) is a selective agonist for Toll-like receptor 7 ( TLR7 ), with an EC 50 of 17.53 nM (for human TLR7 ) and 41.7 nM (for mouse TLR7 ). TLR7 agonist 21 stimulates the secretion of pro-inflammatory cytokines, such as IL-6 , TNF-α, IFN-α1, and IL-4. TLR7 agonist 21 acts as a vaccine adjuvant , increases levels of IgG and IgA , and protects the mouse from influenza virus infections.