Tie2 kinase inhibitor 3 (compound 63) is a potent Tie-2 kinase inhibitor with good oral activity ( IC 50 =30 nM). Tie2 kinase inhibitor 3 inhibits phosphorylation and signaling of Tie-2 by competing with the ATP binding site of Tie-2 kinase. This inhibition affects the stability and maturity of blood vessels, which has an impact on tumor angiogenesis. Tie2 kinase inhibitor 3 can be used to restrict tumor growth and regulate angiogenesis.

规格

英文名称

Tie2 kinase inhibitor 3

储存条件

-20°C储存

运输条件

超低温运输

名称和识别符

分子类型

小分子

分子量

598.59

高级数据

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