托灭酸, AKR1C3 抑制剂

COX-2 Selective Inhibitors

有货

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货号 (SKU)	包装规格	是否现货	价格	数量
T407845-1ml	1ml	现货

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Compound libraries (12332)

基本描述

英文别名	2-[(3-chloro-2-methylphenyl)amino]-benzoic acid
规格或纯度	Moligand™, 10mM in DMSO
英文名称	Tolfenamic Acid
生化机理	olfenamic Acid 是一种 COX-2 抑制剂，其 IC50 值为 0.2 μM。
储存温度	-80℃储存
运输条件	超低温冰袋运输
作用类型	抑制剂
作用机制	AKR1C3 抑制剂
产品介绍	Tolfenamic Acid是一种COX-2抑制剂，IC50为0.2 μM。A non steroidal anti-inflammatory agent found to inhibit COX-2 isoenzymes Information Tolfenamic Acid is aCOX-2inhibitor withIC50of 0.2 μM. In vitro In vivo Cell Data cell lines：RF/MT-2 strains Concentrations： Incubation Time： Powder Purity:≥98%

IC50	COX-2, IC50: 0.2 μM

TTR Tclin 转甲状腺素蛋白(Transthyretin) (1 活性数据)

点击查看靶蛋白信息： TTR

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

AKR1C3 Tchem 醛酮还原酶家族 1 个成员 C3(Aldo-keto reductase family 1 member C3) (2 活性数据)

点击查看靶蛋白信息： AKR1C3

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

溶解性	Solubility (25°C) In vitro DMSO: 62 mg/mL (186.25 mM);

Concentration(Compounding value)	9.0-11.0(mmol/L)
Record the entire process by video	Conform

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

1. Guanqiong Na, Xiaofei Hu, Yaning Sun, Guangxu Xing, Yunrui Xing, Gaiping Zhang. (2020) A novel gold particle-based paper sensor for sensitively detecting carprofen in bovine muscle. FOOD AND AGRICULTURAL IMMUNOLOGY, 31 (1): (463-474). [10.1080/09540105.2020.1740178]
2. Xinyi Wang, Shijie Xu, Lina Jia, Yujia Yang, Yu Liu, Junbo Gong, Songgu Wu. (2019) Drug–drug salts of mefenamic acid\tolfenamic acid and piperazine to improve physicochemical properties for potential veterinary use. CRYSTENGCOMM, 21 (35): (5284-5291). [10.1039/C9CE00781D]
3. Xue Shu-Wen, Li Jing, Xu Li. (2017) Preparation of magnetic melamine-formaldehyde resin and its application to extract nonsteroidal anti-inflammatory drugs. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 409 (12): (3103-3113). [PMID:28224244] [10.1007/s00216-017-0251-8]
4. Luo Zhi-yuan, Li Zhi-yong, Liu Hai-yan, Tang Min-qiong, Shi Zhi-guo. (2015) Click chemistry-based synthesis of water-dispersible hydrophobic magnetic nanoparticles for use in solid phase extraction of non-steroidal anti-inflammatory drugs. MICROCHIMICA ACTA, 182 (15): (2585-2591). [10.1007/s00604-015-1638-x]
5. Chaonan Huang,Yun Li,Jiajia Yang,Junyu Peng,Jun Tan,Yun Fan,Longxing Wang,Jiping Chen. (2018-09-03) Hyperbranched mixed-mode anion-exchange polymeric sorbent for highly selective extraction of nine acidic non-steroidal anti-inflammatory drugs from human urine.. Talanta, 190 (15-22). [PMID:30172492]

1. Guanqiong Na, Xiaofei Hu, Yaning Sun, Guangxu Xing, Yunrui Xing, Gaiping Zhang. (2020) A novel gold particle-based paper sensor for sensitively detecting carprofen in bovine muscle. FOOD AND AGRICULTURAL IMMUNOLOGY, 31 (1): (463-474). [10.1080/09540105.2020.1740178]
2. Xinyi Wang, Shijie Xu, Lina Jia, Yujia Yang, Yu Liu, Junbo Gong, Songgu Wu. (2019) Drug–drug salts of mefenamic acid\tolfenamic acid and piperazine to improve physicochemical properties for potential veterinary use. CRYSTENGCOMM, 21 (35): (5284-5291). [10.1039/C9CE00781D]
3. Xue Shu-Wen, Li Jing, Xu Li. (2017) Preparation of magnetic melamine-formaldehyde resin and its application to extract nonsteroidal anti-inflammatory drugs. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 409 (12): (3103-3113). [PMID:28224244] [10.1007/s00216-017-0251-8]
4. Luo Zhi-yuan, Li Zhi-yong, Liu Hai-yan, Tang Min-qiong, Shi Zhi-guo. (2015) Click chemistry-based synthesis of water-dispersible hydrophobic magnetic nanoparticles for use in solid phase extraction of non-steroidal anti-inflammatory drugs. MICROCHIMICA ACTA, 182 (15): (2585-2591). [10.1007/s00604-015-1638-x]
5. Chaonan Huang,Yun Li,Jiajia Yang,Junyu Peng,Jun Tan,Yun Fan,Longxing Wang,Jiping Chen. (2018-09-03) Hyperbranched mixed-mode anion-exchange polymeric sorbent for highly selective extraction of nine acidic non-steroidal anti-inflammatory drugs from human urine.. Talanta, 190 (15-22). [PMID:30172492]