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| 描述 | 磷脂酰肌醇 4,5-双磷酸 3-激酶催化亚基 α 异构体 |
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基因和蛋白信息
| 基因ID | 5290 |
|---|---|
| Uniprot Accession IDs | P42336 Q14CW1 Q99762 PI3-kinase subunit alpha |
| Ensembl ID | ENSG00000121879 |
| 原子符号 | MCM CWS5 MCAP PI3K CLAPO CLOVE MCMTC PI3K-alpha p110-alpha |
| Chromosome | 3 |
| 家族 | Belongs to the PI3/PI4-kinase family. |
| 序列 |
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMDCFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
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同源基因和蛋白信息
| 同源种属 | 基因编号（Gene ID） | 基因名称（Gene Symbol) | 蛋白名称 | 种属编号（Tax ID) | 其它基因编号（Gene ID） | 来源 |
|---|---|---|---|---|---|---|
| Chimp | 460858 | PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 9598 | VGNC:7083 | OMA, EggNOG |
| Macaque | 709959 | PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 18706 | Pik3ca | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 10090 | MGI:1206581 | Inparanoid, OMA, EggNOG |
| Rat | 170911 | Pik3ca | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | 10116 | RGD:620916 | Inparanoid, OMA |
| Dog | 488084 | PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 9615 | VGNC:44555 | Inparanoid, OMA, EggNOG |
| Horse | 100058141 | PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 9796 | VGNC:21446 | Inparanoid, OMA, EggNOG |
| Cow | 282306 | PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 9913 | VGNC:32889 | Inparanoid, OMA, EggNOG |
| Pig | 100621789 | PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 9823 | OMA, EggNOG | |
| Opossum | 100010412 | PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 13616 | Inparanoid, OMA, EggNOG | |
| Platypus | PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:8975] | 9258 | OMA, EggNOG | ||
| Chicken | 424971 | PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 9031 | CGNC:6785 | Inparanoid, OMA |
| Anole lizard | 100562345 | pik3ca | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | 100144924 | pik3ca | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 8364 | XB-GENE-998106 | Inparanoid, OMA, EggNOG |
蛋白质类别
PANTHER Classes
蛋白质 / transferase / 磷脂酰肌醇 4,5-双磷酸 3-激酶催化亚基 α 异构体
蛋白质 / kinase / 磷脂酰肌醇 4,5-双磷酸 3-激酶催化亚基 α 异构体
蛋白质 / transferase / 磷脂酰肌醇 4,5-双磷酸 3-激酶催化亚基 α 异构体
蛋白质 / kinase / 磷脂酰肌醇 4,5-双磷酸 3-激酶催化亚基 α 异构体
相关重组蛋白
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Associated Approved Drugs
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| 疾病英文名称 | 疾病中文名称 | 疾病类型 | Mondoid | Direct Associated Targets |
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