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PI4KA

描述 磷脂酰肌醇4-激酶α

基因和蛋白信息

基因ID 5297
Uniprot Accession IDs P42356 Q7Z625 Q9UPG2 PI4-kinase alpha
Ensembl ID ENSG00000241973
原子符号 PIK4 PIK4CA PIK4CA PMGYCHA pi4K230 PI4K-ALPHA
Chromosome 22
家族 Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
序列
MAAAPARGGGGGGGGGGGCSGSGSSASRGFYFNTVLSLARSLAVQRPASLEKVQKLLCMCPVDFHGIFQLDERRRDAVIALGIFLIESDLQHKDCVVPYLLRLLKGLPKVYWVEESTARKGRGALPVAESFSFCLVTLLSDVAYRDPSLRDEILEVLLQVLHVLLGMCQALEIQDKEYLCKYAIPCLIGISRAFGRYSNMEESLLSKLFPKIPPHSLRVLEELEGVRRRSFNDFRSILPSNLLTVCQEGTLKRKTSSVSSISQVSPERGMPPPSSPGGSAFHYFEASCLPDGTALEPEYYFSTISSSFSVSPLFNGVTYKEFNIPLEMLRELLNLVKKIVEEAVLKSLDAIVASVMEANPSADLYYTSFSDPLYLTMFKMLRDTLYYMKDLPTSFVKEIHDFVLEQFNTSQGELQKILHDADRIHNELSPLKLRCQANAACVDLMVWAVKDEQGAENLCIKLSEKLQSKTSSKVIIAHLPLLICCLQGLGRLCERFPVVVHSVTPSLRDFLVIPSPVLVKLYKYHSQYHTVAGNDIKISVTNEHSESTLNVMSGKKSQPSMYEQLRDIAIDNICRCLKAGLTVDPVIVEAFLASLSNRLYISQESDKDAHLIPDHTIRALGHIAVALRDTPKVMEPILQILQQKFCQPPSPLDVLIIDQLGCLVITGNQYIYQEVWNLFQQISVKASSVVYSATKDYKDHGYRHCSLAVINALANIAANIQDEHLVDELLMNLLELFVQLGLEGKRASERASEKGPALKASSSAGNLGVLIPVIAVLTRRLPPIKEAKPRLQKLFRDFWLYSVLMGFAVEGSGLWPEEWYEGVCEIATKSPLLTFPSKEPLRSVLQYNSAMKNDTVTPAELSELRSTIINLLDPPPEVSALINKLDFAMSTYLLSVYRLEYMRVLRSTDPDRFQVMFCYFEDKAIQKDKSGMMQCVIAVADKVFDAFLNMMADKAKTKENEEELERHAQFLLVNFNHIHKRIRRVADKYLSGLVDKFPHLLWSGTVLKTMLDILQTLSLSLSADIHKDQPYYDIPDAPYRITVPDTYEARESIVKDFAARCGMILQEAMKWAPTVTKSHLQEYLNKHQNWVSGLSQHTGLAMATESILHFAGYNKQNTTLGATQLSERPACVKKDYSNFMASLNLRNRYAGEVYGMIRFSGTTGQMSDLNKMMVQDLHSALDRSHPQHYTQAMFKLTAMLISSKDCDPQLLHHLCWGPLRMFNEHGMETALACWEWLLAGKDGVEVPFMREMAGAWHMTVEQKFGLFSAEIKEADPLAASEASQPKPCPPEVTPHYIWIDFLVQRFEIAKYCSSDQVEIFSSLLQRSMSLNIGGAKGSMNRHVAAIGPRFKLLTLGLSLLHADVVPNATIRNVLREKIYSTAFDYFSCPPKFPTQGEKRLREDISIMIKFWTAMFSDKKYLTASQLVPPDNQDTRSNLDITVGSRQQATQGWINTYPLSSGMSTISKKSGMSKKTNRGSQLHKYYMKRRTLLLSLLATEIERLITWYNPLSAPELELDQAGENSVANWRSKYISLSEKQWKDNVNLAWSISPYLAVQLPARFKNTEAIGNEVTRLVRLDPGAVSDVPEAIKFLVTWHTIDADAPELSHVLCWAPTDPPTGLSYFSSMYPPHPLTAQYGVKVLRSFPPDAILFYIPQIVQALRYDKMGYVREYILWAASKSQLLAHQFIWNMKTNIYLDEEGHQKDPDIGDLLDQLVEEITGSLSGPAKDFYQREFDFFNKITNVSAIIKPYPKGDERKKACLSALSEVKVQPGCYLPSNPEAIVLDIDYKSGTPMQSAAKAPYLAKFKVKRCGVSELEKEGLRCRSDSEDECSTQEADGQKISWQAAIFKVGDDCRQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQLGRQTDFGMYDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHIIHIDFGFMFESSPGGNLGWEPDIKLTDEMVMIMGGKMEATPFKWFMEMCVRGYLAVRPYMDAVVSLVTLMLDTGLPCFRGQTIKLLKHRFSPNMTEREAANFIMKVIQSCFLSNRSRTYDMIQYYQNDIPY
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同源基因和蛋白信息
同源种属 基因编号（Gene ID） 基因名称（Gene Symbol) 蛋白名称 种属编号（Tax ID) 其它基因编号（Gene ID） 来源
Macaque 698020 PI4KA phosphatidylinositol 4-kinase alpha 9544 Inparanoid, OMA
Mouse 224020 Pi4ka phosphatidylinositol 4-kinase alpha 10090 MGI:2448506 Inparanoid, OMA
Rat 64161 Pi4ka phosphatidylinositol 4-kinase alpha 10116 RGD:621213 Inparanoid, OMA
Dog 486443 PI4KA phosphatidylinositol 4-kinase alpha 9615 Inparanoid, OMA
Horse 100057017 PI4KA phosphatidylinositol 4-kinase alpha 9796 VGNC:50961 Inparanoid, OMA
Cow 282309 PI4KA phosphatidylinositol 4-kinase alpha 9913 Inparanoid, OMA
Opossum 100027724 PI4KA phosphatidylinositol 4-kinase alpha 13616 Inparanoid, OMA
Anole lizard 100554829 pi4ka phosphatidylinositol 4-kinase alpha 28377 Inparanoid, OMA
Xenopus 100127709 pi4ka phosphatidylinositol 4-kinase, catalytic, alpha 8364 XB-GENE-980714 Inparanoid, OMA
Zebrafish 556956 pi4kaa phosphatidylinositol 4-kinase, catalytic, alpha a 7955 ZDB-GENE-100204-2 Inparanoid, OMA

蛋白质类别

PANTHER Classes
蛋白质    /    transferase    /    磷脂酰肌醇4-激酶α
蛋白质    /    kinase    /    磷脂酰肌醇4-激酶α
DTO Classes
蛋白质    /    激酶    /    非蛋白激酶    /    脂质激酶    /    PI3/PI4 激酶家族    /    III 型 PI4K 亚家族    /    磷脂酰肌醇4-激酶α

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Associated Approved Drugs

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疾病英文名称 疾病中文名称 疾病类型 Mondoid Direct Associated Targets

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