| 描述 | eIF-2-alpha 激酶 GCN2 |
|---|
基因和蛋白信息
| 基因ID | 440275 |
|---|---|
| Uniprot Accession IDs | Q9P2K8 C9JEC4 Q69YL7 Q6DC97 Q96GN6 Q9H5K1 Q9NSQ3 Q9NSZ5 Q9UJ56 |
| Ensembl ID | ENSG00000128829 |
| 原子符号 | GCN2 KIAA1338 GCN2 PVOD2 |
| Chromosome | 15 |
| 家族 | Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily. |
| 序列 |
MAGGRGAPGRGRDEPPESYPQRQDHELQALEAIYGADFQDLRPDACGPVKEPPEINLVLYPQGLTGEEVYVKVDLRVKCPPTYPDVVPEIELKNAKGLSNESVNLLKSRLEELAKKHCGEVMIFELAYHVQSFLSEHNKPPPKSFHEEMLERRAQEEQQRLLEAKRKEEQEQREILHEIQRRKEEIKEEKKRKEMAKQERLEIASLSNQDHTSKKDPGGHRTAAILHGGSPDFVGNGKHRANSSGRSRRERQYSVCNSEDSPGSCEILYFNMGSPDQLMVHKGKCIGSDEQLGKLVYNALETATGGFVLLYEWVLQWQKKMGPFLTSQEKEKIDKCKKQIQGTETEFNSLVKLSHPNVVRYLAMNLKEQDDSIVVDILVEHISGVSLAAHLSHSGPIPVHQLRRYTAQLLSGLDYLHSNSVVHKVLSASNVLVDAEGTVKITDYSISKRLADICKEDVFEQTRVRFSDNALPYKTGKKGDVWRLGLLLLSLSQGQECGEYPVTIPSDLPADFQDFLKKCVCLDDKERWSPQQLLKHSFINPQPKMPLVEQSPEDSEGQDYVETVIPSNRLPSAAFFSETQRQFSRYFIEFEELQLLGKGAFGAVIKVQNKLDGCCYAVKRIPINPASRQFRRIKGEVTLLSRLHHENIVRYYNAWIERHERPAGPGTPPPDSGPLAKDDRAARGQPASDTDGLDSVEAAAPPPILSSSVEWSTSGERSASARFPATGPGSSDDEDDDEDEHGGVFSQSFLPASDSESDIIFDNEDENSKSQNQDEDCNEKNGCHESEPSVTTEAVHYLYIQMEYCEKSTLRDTIDQGLYRDTVRLWRLFREILDGLAYIHEKGMIHRDLKPVNIFLDSDDHVKIGDFGLATDHLAFSADSKQDDQTGDLIKSDPSGHLTGMVGTALYVSPEVQGSTKSAYNQKVDLFSLGIIFFEMSYHPMVTASERIFVLNQLRDPTSPKFPEDFDDGEHAKQKSVISWLLNHDPAKRPTATELLKSELLPPPQMEESELHEVLHHTLTNVDGKAYRTMMAQIFSQRISPAIDYTYDSDILKGNFSIRTAKMQQHVCETIIRIFKRHGAVQLCTPLLLPRNRQIYEHNEAALFMDHSGMLVMLPFDLRIPFARYVARNNILNLKRYCIERVFRPRKLDRFHPKELLECAFDIVTSTTNSFLPTAEIIYTIYEIIQEFPALQERNYSIYLNHTMLLKAILLHCGIPEDKLSQVYIILYDAVTEKLTRREVEAKFCNLSLSSNSLCRLYKFIEQKGDLQDLMPTINSLIKQKTGIAQLVKYGLKDLEEVVGLLKKLGIKLQVLINLGLVYKVQQHNGIIFQFVAFIKRRQRAVPEILAAGGRYDLLIPQFRGPQALGPVPTAIGVSIAIDKISAAVLNMEESVTISSCDLLVVSVGQMSMSRAINLTQKLWTAGITAEIMYDWSQSQEELQEYCRHHEITYVALVSDKEGSHVKVKSFEKERQTEKRVLETELVDHVLQKLRTKVTDERNGREASDNLAVQNLKGSFSNASGLFEIHGATVVPIVSVLAPEKLSASTRRRYETQVQTRLQTSLANLHQKSSEIEILAVDLPKETILQFLSLEWDADEQAFNTTVKQLLSRLPKQRYLKLVCDEIYNIKVEKKVSVLFLYSYRDDYYRILF
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同源基因和蛋白信息
| 同源种属 | 基因编号（Gene ID） | 基因名称（Gene Symbol) | 蛋白名称 | 种属编号（Tax ID) | 其它基因编号（Gene ID） | 来源 |
|---|---|---|---|---|---|---|
| Chimp | 453321 | EIF2AK4 | eukaryotic translation initiation factor 2 alpha kinase 4 | 9598 | VGNC:2490 | OMA, EggNOG |
| Mouse | 27103 | Eif2ak4 | eukaryotic translation initiation factor 2 alpha kinase 4 | 10090 | MGI:1353427 | Inparanoid, OMA, EggNOG |
| Rat | 114859 | Eif2ak4 | eukaryotic translation initiation factor 2 alpha kinase 4 | 10116 | RGD:1311439 | Inparanoid, OMA, EggNOG |
| Dog | 478257 | EIF2AK4 | eukaryotic translation initiation factor 2 alpha kinase 4 | 9615 | VGNC:40259 | Inparanoid, OMA, EggNOG |
| Horse | 100071494 | EIF2AK4 | eukaryotic translation initiation factor 2 alpha kinase 4 | 9796 | VGNC:17480 | Inparanoid, OMA, EggNOG |
| Cow | 513829 | EIF2AK4 | eukaryotic translation initiation factor 2 alpha kinase 4 | 9913 | VGNC:28383 | Inparanoid, OMA, EggNOG |
| Opossum | 100031798 | EIF2AK4 | eukaryotic translation initiation factor 2 alpha kinase 4 | 13616 | Inparanoid, EggNOG | |
| Platypus | EIF2AK4 | eukaryotic translation initiation factor 2 alpha kinase 4 [Source:HGNC Symbol;Acc:HGNC:19687] | 9258 | OMA, EggNOG | ||
| Chicken | 423285 | EIF2AK4 | eukaryotic translation initiation factor 2 alpha kinase 4 | 9031 | CGNC:7318 | Inparanoid, OMA |
| Anole lizard | 100552145 | eif2ak4 | eukaryotic translation initiation factor 2 alpha kinase 4 | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | eif2ak4 | eukaryotic translation initiation factor 2 alpha kinase 4 [Source:Xenbase;Acc:XB-GENE-967321] | 8364 | OMA, EggNOG | ||
| C. elegans | 174953 | gcn-2 | Eukaryotic translation initiation factor 2-alpha kinase gcn-2 | 6239 | Inparanoid, OMA | |
| Fruitfly | 43709 | Gcn2 | CG1609 gene product from transcript CG1609-RA | 7227 | FBgn0019990 | Inparanoid, EggNOG |
| S.cerevisiae | 851877 | GCN2 | serine/threonine-protein kinase GCN2 | 4932 | S000002691 | Inparanoid, OMA, EggNOG |
蛋白质类别
PANTHER Classes
蛋白质 / non-receptor serine/threonine protein kinase / 真核翻译起始因子 2-α激酶 4
蛋白质 / protein kinase / 真核翻译起始因子 2-α激酶 4
蛋白质 / transferase / 真核翻译起始因子 2-α激酶 4
蛋白质 / kinase / 真核翻译起始因子 2-α激酶 4
蛋白质 / non-receptor serine/threonine protein kinase / 真核翻译起始因子 2-α激酶 4
蛋白质 / protein kinase / 真核翻译起始因子 2-α激酶 4
蛋白质 / transferase / 真核翻译起始因子 2-α激酶 4
蛋白质 / kinase / 真核翻译起始因子 2-α激酶 4
相关重组蛋白
| 蛋白名称 | 规格与纯度 | 表达系统 | 蛋白标签 | 是否现货 | 查看详情 |
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相关抗体
| 名称 | 规格与纯度 | 种属反应性 | 应用 | 是否现货 | 查看详情 |
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Associated Approved Drugs
相关活性配体
相关疾病
| 疾病英文名称 | 疾病中文名称 | 疾病类型 | Mondoid | Direct Associated Targets |
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引用文献
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