| 描述 | 丝氨酸/苏氨酸蛋白激酶 ATR |
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基因和蛋白信息
| 基因ID | 545 |
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| Uniprot Accession IDs | Q13535 Q59HB2 Q7KYL3 Q93051 Q9BXK4 |
| Ensembl ID | ENSG00000175054 |
| 原子符号 | FRP1 FRP1 MEC1 SCKL FCTCS SCKL1 |
| Chromosome | 3 |
| 家族 | Belongs to the PI3/PI4-kinase family. ATM subfamily. |
| 序列 |
MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSHEAKGSCIEFSNWIITRLLRIAATPSCHLLHKKICEVICSLLFLFKSKSPAIFGVLTKELLQLFEDLVYLHRRNVMGHAVEWPVVMSRFLSQLDEHMGYLQSAPLQLMSMQNLEFIEVTLLMVLTRIIAIVFFRRQELLLWQIGCVLLEYGSPKIKSLAISFLTELFQLGGLPAQPASTFFSSFLELLKHLVEMDTDQLKLYEEPLSKLIKTLFPFEAEAYRNIEPVYLNMLLEKLCVMFEDGVLMRLKSDLLKAALCHLLQYFLKFVPAGYESALQVRKVYVRNICKALLDVLGIEVDAEYLLGPLYAALKMESMEIIEEIQCQTQQENLSSNSDGISPKRRRLSSSLNPSKRAPKQTEEIKHVDMNQKSILWSALKQKAESLQISLEYSGLKNPVIEMLEGIAVVLQLTALCTVHCSHQNMNCRTFKDCQHKSKKKPSVVITWMSLDFYTKVLKSCRSLLESVQKLDLEATIDKVVKIYDALIYMQVNSSFEDHILEDLCGMLSLPWIYSHSDDGCLKLTTFAANLLTLSCRISDSYSPQAQSRCVFLLTLFPRRIFLEWRTAVYNWALQSSHEVIRASCVSGFFILLQQQNSCNRVPKILIDKVKDDSDIVKKEFASILGQLVCTLHGMFYLTSSLTEPFSEHGHVDLFCRNLKATSQHECSSSQLKASVCKPFLFLLKKKIPSPVKLAFIDNLHHLCKHLDFREDETDVKAVLGTLLNLMEDPDKDVRVAFSGNIKHILESLDSEDGFIKELFVLRMKEAYTHAQISRNNELKDTLILTTGDIGRAAKGDLVPFALLHLLHCLLSKSASVSGAAYTEIRALVAAKSVKLQSFFSQYKKPICQFLVESLHSSQMTALPNTPCQNADVRKQDVAHQREMALNTLSEIANVFDFPDLNRFLTRTLQVLLPDLAAKASPAASALIRTLGKQLNVNRREILINNFKYIFSHLVCSCSKDELERALHYLKNETEIELGSLLRQDFQGLHNELLLRIGEHYQQVFNGLSILASFASSDDPYQGPRDIISPELMADYLQPKLLGILAFFNMQLLSSSVGIEDKKMALNSLMSLMKLMGPKHVSSVRVKMMTTLRTGLRFKDDFPELCCRAWDCFVRCLDHACLGSLLSHVIVALLPLIHIQPKETAAIFHYLIIENRDAVQDFLHEIYFLPDHPELKKIKAVLQEYRKETSESTDLQTTLQLSMKAIQHENVDVRIHALTSLKETLYKNQEKLIKYATDSETVEPIISQLVTVLLKGCQDANSQARLLCGECLGELGAIDPGRLDFSTTETQGKDFTFVTGVEDSSFAYGLLMELTRAYLAYADNSRAQDSAAYAIQELLSIYDCREMETNGPGHQLWRRFPEHVREILEPHLNTRYKSSQKSTDWSGVKKPIYLSKLGSNFAEWSASWAGYLITKVRHDLASKIFTCCSIMMKHDFKVTIYLLPHILVYVLLGCNQEDQQEVYAEIMAVLKHDDQHTINTQDIASDLCQLSTQTVFSMLDHLTQWARHKFQALKAEKCPHSKSNRNKVDSMVSTVDYEDYQSVTRFLDLIPQDTLAVASFRSKAYTRAVMHFESFITEKKQNIQEHLGFLQKLYAAMHEPDGVAGVSAIRKAEPSLKEQILEHESLGLLRDATACYDRAIQLEPDQIIHYHGVVKSMLGLGQLSTVITQVNGVHANRSEWTDELNTYRVEAAWKLSQWDLVENYLAADGKSTTWSVRLGQLLLSAKKRDITAFYDSLKLVRAEQIVPLSAASFERGSYQRGYEYIVRLHMLCELEHSIKPLFQHSPGDSSQEDSLNWVARLEMTQNSYRAKEPILALRRALLSLNKRPDYNEMVGECWLQSARVARKAGHHQTAYNALLNAGESRLAELYVERAKWLWSKGDVHQALIVLQKGVELCFPENETPPEGKNMLIHGRAMLLVGRFMEETANFESNAIMKKYKDVTACLPEWEDGHFYLAKYYDKLMPMVTDNKMEKQGDLIRYIVLHFGRSLQYGNQFIYQSMPRMLTLWLDYGTKAYEWEKAGRSDRVQMRNDLGKINKVITEHTNYLAPYQFLTAFSQLISRICHSHDEVFVVLMEIIAKVFLAYPQQAMWMMTAVSKSSYPMRVNRCKEILNKAIHMKKSLEKFVGDATRLTDKLLELCNKPVDGSSSTLSMSTHFKMLKKLVEEATFSEILIPLQSVMIPTLPSILGTHANHASHEPFPGHWAYIAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKCLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYMTGKELRQCMLPKSAALSEKLKVFREFLLPRHPPIFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGETFEVPEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEWSKPVKGHSKAPLNETGEVVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHYLIQEATDENLLCQMYLGWTPYM
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同源基因和蛋白信息
| 同源种属 | 基因编号（Gene ID） | 基因名称（Gene Symbol) | 蛋白名称 | 种属编号（Tax ID) | 其它基因编号（Gene ID） | 来源 |
|---|---|---|---|---|---|---|
| Chimp | 460745 | ATR | ATR serine/threonine kinase | 9598 | VGNC:6166 | OMA, EggNOG |
| Macaque | 714443 | ATR | ATR serine/threonine kinase | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 245000 | Atr | ataxia telangiectasia and Rad3 related | 10090 | MGI:108028 | Inparanoid, OMA, EggNOG |
| Rat | 685055 | Atr | ATR serine/threonine kinase | 10116 | RGD:1305796 | Inparanoid, OMA, EggNOG |
| Dog | 100856315 | ATR | ATR serine/threonine kinase | 9615 | VGNC:38293 | Inparanoid, OMA, EggNOG |
| Horse | 100062529 | ATR | ATR serine/threonine kinase | 9796 | VGNC:15692 | Inparanoid, OMA, EggNOG |
| Cow | 504869 | ATR | ATR serine/threonine kinase | 9913 | VGNC:26334 | Inparanoid, OMA, EggNOG |
| Pig | 100516227 | ATR | ATR serine/threonine kinase | 9823 | OMA, EggNOG | |
| Opossum | 100019691 | ATR | ATR serine/threonine kinase | 13616 | Inparanoid, OMA, EggNOG | |
| Chicken | 424777 | ATR | ATR serine/threonine kinase | 9031 | CGNC:1918 | OMA, EggNOG |
| Anole lizard | 100561948 | atr | ATR serine/threonine kinase | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | 100495593 | atr | ATR serine/threonine kinase | 8364 | XB-GENE-1012722 | Inparanoid, OMA, EggNOG |
| Zebrafish | 567770 | atr | ATR serine/threonine kinase | 7955 | ZDB-GENE-070912-458 | Inparanoid, OMA |
| Fruitfly | 32608 | mei-41 | meiotic 41 | 7227 | FBgn0004367 | Inparanoid, EggNOG |
| S.cerevisiae | 852433 | MEC1 | protein kinase MEC1 | 4932 | S000000340 | Inparanoid, EggNOG |
蛋白质类别
PANTHER Classes
蛋白质 / non-receptor serine/threonine protein kinase / 丝氨酸/苏氨酸蛋白激酶 atr
蛋白质 / protein kinase / 丝氨酸/苏氨酸蛋白激酶 atr
蛋白质 / nucleotide kinase / 丝氨酸/苏氨酸蛋白激酶 atr
蛋白质 / transferase / 丝氨酸/苏氨酸蛋白激酶 atr
蛋白质 / kinase / 丝氨酸/苏氨酸蛋白激酶 atr
蛋白质 / nucleic acid binding / 丝氨酸/苏氨酸蛋白激酶 atr
蛋白质 / non-receptor serine/threonine protein kinase / 丝氨酸/苏氨酸蛋白激酶 atr
蛋白质 / protein kinase / 丝氨酸/苏氨酸蛋白激酶 atr
蛋白质 / nucleotide kinase / 丝氨酸/苏氨酸蛋白激酶 atr
蛋白质 / transferase / 丝氨酸/苏氨酸蛋白激酶 atr
蛋白质 / kinase / 丝氨酸/苏氨酸蛋白激酶 atr
蛋白质 / nucleic acid binding / 丝氨酸/苏氨酸蛋白激酶 atr
相关重组蛋白
| 蛋白名称 | 规格与纯度 | 表达系统 | 蛋白标签 | 是否现货 | 查看详情 |
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相关抗体
| 名称 | 规格与纯度 | 种属反应性 | 应用 | 是否现货 | 查看详情 |
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Associated Approved Drugs
相关活性配体
相关疾病
| 疾病英文名称 | 疾病中文名称 | 疾病类型 | Mondoid | Direct Associated Targets |
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引用文献
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