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WNK1

描述 丝氨酸/苏氨酸蛋白激酶 WNK1

基因和蛋白信息

基因ID 65125
Uniprot Accession IDs Q9H4A3 A1L4B0 C5HTZ5 C5HTZ6 C5HTZ7 H6WZW3 O15052 P54963 Q4VBX9 Q6IFS5 Q86WL5 Q8N673 Q96CZ6 Q9P1S9
Ensembl ID ENSG00000060237
原子符号 HSN2 KDP KIAA0344 PRKWNK1 KDP PSK p65 HSN2 HSAN2 PRKWNK1 PPP1R167
Chromosome 12
家族 Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WNK subfamily.
序列
MSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGAAAADAVTGRTEEYRRRRHTMDKDSRGAAATTTTTEHRFFRRSVICDSNATALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPPARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNHAFFQEETGVRVELAEEDDGEKIAIKLWLRIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQEMVESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKKKQEESSLKQQVEQSSASQTGIKQLPSASTGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVAQGQSQGQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQAPQVLPQVSAGKQLPVSQPVPTIQGEPQIPVATQPSVVPVHSGAHFLPVGQPLPTPLLPQYPVSQIPISTPHVSTAQTGFSSLPITMAAGITQPLLTLASSATTAAIPGVSTVVPSQLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPPQYPGDSNIAPSSNVASVCIHSTVLSPPMPTEVLATPGYFPTVVQPYVESNLLVPMGGVGGQVQVSQPGGSLAQAPTTSSQQAVLESTQGVSQVAPAEPVAVAQTQATQPTTLASSVDSAHSDVASGMSDGNENVPSSSGRHEGRTTKRHYRKSVRSRSRHEKTSRPKLRILNVSNKGDRVVECQLETHNRKMVTFKFDLDGDNPEEIATIMVNNDFILAIERESFVDQVREIIEKADEMLSEDVSVEPEGDQGLESLQGKDDYGFSGSQKLEGEFKQPIPASSMPQQIGIPTSSLTQVVHSAGRRFIVSPVPESRLRESKVFPSEITDTVAASTAQSPGMNLSHSASSLSLQQAFSELRRAQMTEGPNTAPPNFSHTGPTFPVVPPFLSSIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIAGVATSTGVVTSGGLPIPPVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEIVVSSTALYPSVTVSATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLCIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIPSVIASTPILPQAAGPTSTPLLPQVPSIPPLVQPVANVPAVQQTLIHSQPQPALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVSTTTSGVKPGTAPSKPPLTKAPVLPVGTELPAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQLRRTLSPEMITVTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEGPVLATSSGAGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHFESSTSESSVLSSSSPESTLVKPEPNGITIPGISSDVPESAHKTTASEAKSDTGQPTKVGRFQVTTTANKVGRFSVSKTEDKITDTKKEGPVASPPFMDLEQAVLPAVIPKKEKPELSEPSHLNGPSSDPEAAFLSRDVDDGSGSPHSPHQLSSKSLPSQNLSQSLSNSFNSSYMSSDNESDIEDEDLKLELRRLRDKHLKEIQDLQSRQKHEIESLYTKLGKVPPAVIIPPAAPLSGRRRRPTKSKGSKSSRSSSLGNKSPQLSGNLSGQSAASVLHPQQTLHPPGNIPESGQNQLLQPLKPSPSSDNLYSAFTSDGAISVPSLSAPGQGTSSTNTVGATVNSQAAQAQPPAMTSSRKGTFTDDLHKLVDNWARDAMNLSGRRGSKGHMNYEGPGMARKFSAPGQLCISMTSNLGGSAPISAASATSLGHFTKSMCPPQQYGFPATPFGAQWSGTGGPAPQPLGQFQPVGTASLQNFNISNLQKSISNPPGSNLRTT
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同源基因和蛋白信息
同源种属 基因编号（Gene ID） 基因名称（Gene Symbol) 蛋白名称 种属编号（Tax ID) 其它基因编号（Gene ID） 来源
Chimp 451739 WNK1 WNK lysine deficient protein kinase 1 9598 VGNC:13495 Inparanoid, OMA, EggNOG
Macaque 706493 WNK1 WNK lysine deficient protein kinase 1 9544 Inparanoid, OMA, EggNOG
Mouse 232341 Wnk1 WNK lysine deficient protein kinase 1 10090 MGI:2442092 Inparanoid, OMA, EggNOG
Rat 116477 Wnk1 WNK lysine deficient protein kinase 1 10116 RGD:621141 Inparanoid, OMA, EggNOG
Dog 477728 WNK1 WNK lysine deficient protein kinase 1 9615 VGNC:48418 Inparanoid, OMA, EggNOG
Horse 100056745 WNK1 WNK lysine deficient protein kinase 1 9796 VGNC:52460 Inparanoid, OMA, EggNOG
Cow 506433 WNK1 WNK lysine deficient protein kinase 1 9913 VGNC:36949 Inparanoid, OMA, EggNOG
Pig 406235 WNK1 WNK lysine deficient protein kinase 1 9823 OMA, EggNOG
Opossum 100017207 WNK1 WNK lysine deficient protein kinase 1 13616 Inparanoid, OMA, EggNOG
Chicken 427925 WNK1 WNK lysine deficient protein kinase 1 9031 CGNC:9833 OMA, EggNOG
Anole lizard 100552658 wnk1 WNK lysine deficient protein kinase 1 28377 Inparanoid, OMA, EggNOG
Xenopus 100036683 wnk1 WNK lysine deficient protein kinase 1 8364 XB-GENE-877004 Inparanoid, OMA, EggNOG
Zebrafish 561159 wnk1b WNK lysine deficient protein kinase 1b 7955 ZDB-GENE-030131-2656 Inparanoid, OMA

蛋白质类别

PANTHER Classes
蛋白质    /    non-receptor serine/threonine protein kinase    /    丝氨酸/苏氨酸蛋白激酶 wnk1
蛋白质    /    protein kinase    /    丝氨酸/苏氨酸蛋白激酶 wnk1
蛋白质    /    transferase    /    丝氨酸/苏氨酸蛋白激酶 wnk1
蛋白质    /    kinase    /    丝氨酸/苏氨酸蛋白激酶 wnk1
DTO Classes
蛋白质    /    激酶    /    蛋白激酶    /    其他组    /    WNK 家族    /    丝氨酸/苏氨酸蛋白激酶 wnk1

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Associated Approved Drugs

相关活性配体

相关疾病

疾病英文名称 疾病中文名称 疾病类型 Mondoid Direct Associated Targets

引用文献

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