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ABCC8

描述 ATP 结合盒亚家族 C 成员 8

基因和蛋白信息

基因ID 6833
Uniprot Accession IDs Q09428 A6NMX8 E3UYX6 O75948 Q16583
Ensembl ID ENSG00000006071
原子符号 HRINS SUR SUR1 HI SUR HHF1 MRP8 PHHI SUR1 ABC36 HRINS TNDM2 SUR1delta2
Chromosome 11
家族 Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
序列
MPLAFCGSENHSAAYRVDQGVLNNGCFVDALNVVPHVFLLFITFPILFIGWGSQSSKVHIHHSTWLHFPGHNLRWILTFMLLFVLVCEIAEGILSDGVTESHHLHLYMPAGMAFMAAVTSVVYYHNIETSNFPKLLIALLVYWTLAFITKTIKFVKFLDHAIGFSQLRFCLTGLLVILYGMLLLVEVNVIRVRRYIFFKTPREVKPPEDLQDLGVRFLQPFVNLLSKGTYWWMNAFIKTAHKKPIDLRAIGKLPIAMRALTNYQRLCEAFDAQVRKDIQGTQGARAIWQALSHAFGRRLVLSSTFRILADLLGFAGPLCIFGIVDHLGKENDVFQPKTQFLGVYFVSSQEFLANAYVLAVLLFLALLLQRTFLQASYYVAIETGINLRGAIQTKIYNKIMHLSTSNLSMGEMTAGQICNLVAIDTNQLMWFFFLCPNLWAMPVQIIVGVILLYYILGVSALIGAAVIILLAPVQYFVATKLSQAQRSTLEYSNERLKQTNEMLRGIKLLKLYAWENIFRTRVETTRRKEMTSLRAFAIYTSISIFMNTAIPIAAVLITFVGHVSFFKEADFSPSVAFASLSLFHILVTPLFLLSSVVRSTVKALVSVQKLSEFLSSAEIREEQCAPHEPTPQGPASKYQAVPLRVVNRKRPAREDCRGLTGPLQSLVPSADGDADNCCVQIMGGYFTWTPDGIPTLSNITIRIPRGQLTMIVGQVGCGKSSLLLAALGEMQKVSGAVFWSSLPDSEIGEDPSPERETATDLDIRKRGPVAYASQKPWLLNATVEENIIFESPFNKQRYKMVIEACSLQPDIDILPHGDQTQIGERGINLSGGQRQRISVARALYQHANVVFLDDPFSALDIHLSDHLMQAGILELLRDDKRTVVLVTHKLQYLPHADWIIAMKDGTIQREGTLKDFQRSECQLFEHWKTLMNRQDQELEKETVTERKATEPPQGLSRAMSSRDGLLQDEEEEEEEAAESEEDDNLSSMLHQRAEIPWRACAKYLSSAGILLLSLLVFSQLLKHMVLVAIDYWLAKWTDSALTLTPAARNCSLSQECTLDQTVYAMVFTVLCSLGIVLCLVTSVTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLGSILNRFSSDCNTIDQHIPSTLECLSRSTLLCVSALAVISYVTPVFLVALLPLAIVCYFIQKYFRVASRDLQQLDDTTQLPLLSHFAETVEGLTTIRAFRYEARFQQKLLEYTDSNNIASLFLTAANRWLEVRMEYIGACVVLIAAVTSISNSLHRELSAGLVGLGLTYALMVSNYLNWMVRNLADMELQLGAVKRIHGLLKTEAESYEGLLAPSLIPKNWPDQGKIQIQNLSVRYDSSLKPVLKHVNALIAPGQKIGICGRTGSGKSSFSLAFFRMVDTFEGHIIIDGIDIAKLPLHTLRSRLSIILQDPVLFSGTIRFNLDPERKCSDSTLWEALEIAQLKLVVKALPGGLDAIITEGGENFSQGQRQLFCLARAFVRKTSIFIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILSADLVIVLKRGAILEFDKPEKLLSRKDSVFASFVRADK
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同源基因和蛋白信息
同源种属 基因编号（Gene ID） 基因名称（Gene Symbol) 蛋白名称 种属编号（Tax ID) 其它基因编号（Gene ID） 来源
Chimp 451056 ABCC8 ATP binding cassette subfamily C member 8 9598 VGNC:11253 OMA, EggNOG
Macaque 654490 ABCC8 ATP binding cassette subfamily C member 8 9544 Inparanoid, OMA
Mouse 20927 Abcc8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 10090 MGI:1352629 Inparanoid, OMA, EggNOG
Rat 25559 Abcc8 ATP binding cassette subfamily C member 8 10116 RGD:3786 Inparanoid, OMA, EggNOG
Dog 485402 ABCC8 ATP binding cassette subfamily C member 8 9615 VGNC:37443 Inparanoid, OMA
Horse 100071788 ABCC8 ATP binding cassette subfamily C member 8 9796 VGNC:14921 Inparanoid, OMA
Cow 538996 ABCC8 ATP binding cassette subfamily C member 8 9913 VGNC:25475 Inparanoid, OMA, EggNOG
Pig 100158245 ABCC8 ATP binding cassette subfamily C member 8 9823 Inparanoid, OMA, EggNOG
Opossum 100020181 ABCC8 ATP binding cassette subfamily C member 8 13616 Inparanoid, OMA
Platypus ABCC8 ATP binding cassette subfamily C member 8 [Source:HGNC Symbol;Acc:HGNC:59] 9258 OMA, EggNOG
Chicken 423072 ABCC8 ATP binding cassette subfamily C member 8 9031 CGNC:4631 Inparanoid, OMA, EggNOG
Anole lizard 100562467 abcc8 ATP binding cassette subfamily C member 8 28377 Inparanoid, OMA
Zebrafish 553281 abcc8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 7955 ZDB-GENE-050517-22 Inparanoid, OMA

蛋白质类别

PANTHER Classes
蛋白质    /    transporter    /    ATP-binding cassette (ABC) transporter    /    ATP 结合盒亚家族 C 成员 8
DTO Classes
蛋白质    /    运输者    /    ATP结合盒转运蛋白家族    /    ABCC亚家族    /    ATP 结合盒亚家族 C 成员 8

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Associated Approved Drugs

相关活性配体

相关疾病

疾病英文名称 疾病中文名称 疾病类型 Mondoid Direct Associated Targets

引用文献

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