| 描述 | 丝氨酸蛋白激酶 ATM |
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基因和蛋白信息
| 基因ID | 472 |
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| Uniprot Accession IDs | Q13315 B2RNX5 O15429 Q12758 Q16551 Q93007 Q9NP02 Q9UCX7 |
| Ensembl ID | ENSG00000149311 |
| 原子符号 | AT1 ATA ATC ATD ATE ATDC TEL1 TELO1 |
| Chromosome | 11 |
| 家族 | Belongs to the PI3/PI4-kinase family. ATM subfamily. |
| 序列 |
MSLVLNDLLICCRQLEHDRATERKKEVEKFKRLIRDPETIKHLDRHSDSKQGKYLNWDAVFRFLQKYIQKETECLRIAKPNVSASTQASRQKKMQEISSLVKYFIKCANRRAPRLKCQELLNYIMDTVKDSSNGAIYGADCSNILLKDILSVRKYWCEISQQQWLELFSVYFRLYLKPSQDVHRVLVARIIHAVTKGCCSQTDGLNSKFLDFFSKAIQCARQEKSSSGLNHILAALTIFLKTLAVNFRIRVCELGDEILPTLLYIWTQHRLNDSLKEVIIELFQLQIYIHHPKGAKTQEKGAYESTKWRSILYNLYDLLVNEISHIGSRGKYSSGFRNIAVKENLIELMADICHQVFNEDTRSLEISQSYTTTQRESSDYSVPCKRKKIELGWEVIKDHLQKSQNDFDLVPWLQIATQLISKYPASLPNCELSPLLMILSQLLPQQRHGERTPYVLRCLTEVALCQDKRSNLESSQKSDLLKLWNKIWCITFRGISSEQIQAENFGLLGAIIQGSLVEVDREFWKLFTGSACRPSCPAVCCLTLALTTSIVPGTVKMGIEQNMCEVNRSFSLKESIMKWLLFYQLEGDLENSTEVPPILHSNFPHLVLEKILVSLTMKNCKAAMNFFQSVPECEHHQKDKEELSFSEVEELFLQTTFDKMDFLTIVRECGIEKHQSSIGFSVHQNLKESLDRCLLGLSEQLLNNYSSEITNSETLVRCSRLLVGVLGCYCYMGVIAEEEAYKSELFQKAKSLMQCAGESITLFKNKTNEEFRIGSLRNMMQLCTRCLSNCTKKSPNKIASGFFLRLLTSKLMNDIADICKSLASFIKKPFDRGEVESMEDDTNGNLMEVEDQSSMNLFNDYPDSSVSDANEPGESQSTIGAINPLAEEYLSKQDLLFLDMLKFLCLCVTTAQTNTVSFRAADIRRKLLMLIDSSTLEPTKSLHLHMYLMLLKELPGEEYPLPMEDVLELLKPLSNVCSLYRRDQDVCKTILNHVLHVVKNLGQSNMDSENTRDAQGQFLTVIGAFWHLTKERKYIFSVRMALVNCLKTLLEADPYSKWAILNVMGKDFPVNEVFTQFLADNHHQVRMLAAESINRLFQDTKGDSSRLLKALPLKLQQTAFENAYLKAQEGMREMSHSAENPETLDEIYNRKSVLLTLIAVVLSCSPICEKQALFALCKSVKENGLEPHLVKKVLEKVSETFGYRRLEDFMASHLDYLVLEWLNLQDTEYNLSSFPFILLNYTNIEDFYRSCYKVLIPHLVIRSHFDEVKSIANQIQEDWKSLLTDCFPKILVNILPYFAYEGTRDSGMAQQRETATKVYDMLKSENLLGKQIDHLFISNLPEIVVELLMTLHEPANSSASQSTDLCDFSGDLDPAPNPPHFPSHVIKATFAYISNCHKTKLKSILEILSKSPDSYQKILLAICEQAAETNNVYKKHRILKIYHLFVSLLLKDIKSGLGGAWAFVLRDVIYTLIHYINQRPSCIMDVSLRSFSLCCDLLSQVCQTAVTYCKDALENHLHVIVGTLIPLVYEQVEVQKQVLDLLKYLVIDNKDNENLYITIKLLDPFPDHVVFKDLRITQQKIKYSRGPFSLLEEINHFLSVSVYDALPLTRLEGLKDLRRQLELHKDQMVDIMRASQDNPQDGIMVKLVVNLLQLSKMAINHTGEKEVLEAVGSCLGEVGPIDFSTIAIQHSKDASYTKALKLFEDKELQWTFIMLTYLNNTLVEDCVKVRSAAVTCLKNILATKTGHSFWEIYKMTTDPMLAYLQPFRTSRKKFLEVPRFDKENPFEGLDDINLWIPLSENHDIWIKTLTCAFLDSGGTKCEILQLLKPMCEVKTDFCQTVLPYLIHDILLQDTNESWRNLLSTHVQGFFTSCLRHFSQTSRSTTPANLDSESEHFFRCCLDKKSQRTMLAVVDYMRRQKRPSSGTIFNDAFWLDLNYLEVAKVAQSCAAHFTALLYAEIYADKKSMDDQEKRSLAFEEGSQSTTISSLSEKSKEETGISLQDLLLEIYRSIGEPDSLYGCGGGKMLQPITRLRTYEHEAMWGKALVTYDLETAIPSSTRQAGIIQALQNLGLCHILSVYLKGLDYENKDWCPELEELHYQAAWRNMQWDHCTSVSKEVEGTSYHESLYNALQSLRDREFSTFYESLKYARVKEVEEMCKRSLESVYSLYPTLSRLQAIGELESIGELFSRSVTHRQLSEVYIKWQKHSQLLKDSDFSFQEPIMALRTVILEILMEKEMDNSQRECIKDILTKHLVELSILARTFKNTQLPERAIFQIKQYNSVSCGVSEWQLEEAQVFWAKKEQSLALSILKQMIKKLDASCAANNPSLKLTYTECLRVCGNWLAETCLENPAVIMQTYLEKAVEVAGNYDGESSDELRNGKMKAFLSLARFSDTQYQRIENYMKSSEFENKQALLKRAKEEVGLLREHKIQTNRYTVKVQRELELDELALRALKEDRKRFLCKAVENYINCLLSGEEHDMWVFRLCSLWLENSGVSEVNGMMKRDGMKIPTYKFLPLMYQLAARMGTKMMGGLGFHEVLNNLISRISMDHPHHTLFIILALANANRDEFLTKPEVARRSRITKNVPKQSSQLDEDRTEAANRIICTIRSRRPQMVRSVEALCDAYIILANLDATQWKTQRKGINIPADQPITKLKNLEDVVVPTMEIKVDHTGEYGNLVTIQSFKAEFRLAGGVNLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQRNTETRKRKLTICTYKVVPLSQRSGVLEWCTGTVPIGEFLVNNEDGAHKRYRPNDFSAFQCQKKMMEVQKKSFEEKYEVFMDVCQNFQPVFRYFCMEKFLDPAIWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRNSQETLLTIVEVLLYDPLFDWTMNPLKALYLQQRPEDETELHPTLNADDQECKRNLSDIDQSFNKVAERVLMRLQEKLKGVEEGTVLSVGGQVNLLIQQAIDPKNLSRLFPGWKAWV
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同源基因和蛋白信息
| 同源种属 | 基因编号（Gene ID） | 基因名称（Gene Symbol) | 蛋白名称 | 种属编号（Tax ID) | 其它基因编号（Gene ID） | 来源 |
|---|---|---|---|---|---|---|
| Chimp | 451530 | ATM | ATM serine/threonine kinase | 9598 | VGNC:11264 | OMA, EggNOG |
| Macaque | 100427400 | ATM | ATM serine/threonine kinase | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 11920 | Atm | ataxia telangiectasia mutated | 10090 | MGI:107202 | Inparanoid, OMA, EggNOG |
| Rat | 300711 | Atm | ATM serine/threonine kinase | 10116 | RGD:1593265 | Inparanoid, OMA, EggNOG |
| Dog | 479450 | ATM | ATM serine/threonine kinase | 9615 | VGNC:38233 | Inparanoid, OMA, EggNOG |
| Horse | 100061765 | ATM | ATM serine/threonine kinase | 9796 | VGNC:15634 | Inparanoid, OMA, EggNOG |
| Cow | 526824 | ATM | ATM serine/threonine kinase | 9913 | VGNC:26268 | Inparanoid, OMA, EggNOG |
| Pig | 100101922 | ATM | ATM serine/threonine kinase | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100026797 | ATM | ATM serine/threonine kinase | 13616 | Inparanoid, OMA, EggNOG | |
| Chicken | 395401 | ATM | ATM serine/threonine kinase | 9031 | CGNC:12888 | Inparanoid, OMA, EggNOG |
| Anole lizard | 100556408 | LOC100556408 | serine-protein kinase ATM | 28377 | OMA, EggNOG | |
| Xenopus | 100490767 | atm | ATM serine/threonine kinase | 8364 | XB-GENE-493810 | Inparanoid, OMA, EggNOG |
| Zebrafish | 403064 | atm | ATM serine/threonine kinase | 7955 | ZDB-GENE-040809-1 | Inparanoid, OMA |
| Fruitfly | 41839 | tefu | telomere fusion | 7227 | FBgn0045035 | Inparanoid, EggNOG |
蛋白质类别
PANTHER Classes
蛋白质 / non-receptor serine/threonine protein kinase / 丝氨酸蛋白激酶atm
蛋白质 / protein kinase / 丝氨酸蛋白激酶atm
蛋白质 / nucleotide kinase / 丝氨酸蛋白激酶atm
蛋白质 / transferase / 丝氨酸蛋白激酶atm
蛋白质 / kinase / 丝氨酸蛋白激酶atm
蛋白质 / nucleic acid binding / 丝氨酸蛋白激酶atm
蛋白质 / non-receptor serine/threonine protein kinase / 丝氨酸蛋白激酶atm
蛋白质 / protein kinase / 丝氨酸蛋白激酶atm
蛋白质 / nucleotide kinase / 丝氨酸蛋白激酶atm
蛋白质 / transferase / 丝氨酸蛋白激酶atm
蛋白质 / kinase / 丝氨酸蛋白激酶atm
蛋白质 / nucleic acid binding / 丝氨酸蛋白激酶atm
相关重组蛋白
| 蛋白名称 | 规格与纯度 | 表达系统 | 蛋白标签 | 是否现货 | 查看详情 |
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相关抗体
| 名称 | 规格与纯度 | 种属反应性 | 应用 | 是否现货 | 查看详情 |
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Associated Approved Drugs
相关活性配体
相关疾病
| 疾病英文名称 | 疾病中文名称 | 疾病类型 | Mondoid | Direct Associated Targets |
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引用文献
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