MTOR

描述	丝氨酸/苏氨酸蛋白激酶 mTOR

基因和蛋白信息

基因ID	2475
Uniprot Accession IDs	P42345 Q4LE76 Q5TER1 Q6LE87 Q96QG3 Q9Y4I3
Ensembl ID	ENSG00000198793
原子符号	FRAP FRAP1 FRAP2 RAFT1 RAPT1 SKS FRAP FRAP1 FRAP2 RAFT1 RAPT1
Chromosome	1
家族	Belongs to the PI3/PI4-kinase family.
序列	MLGTGPAAATTAATTSSNVSVLQQFASGLKSRNEETRAKAAKELQHYVTMELREMSQEESTRFYDQLNHHIFELVSSSDANERKGGILAIASLIGVEGGNATRIGRFANYLRNLLPSNDPVVMEMASKAIGRLAMAGDTFTAEYVEFEVKRALEWLGADRNEGRRHAAVLVLRELAISVPTFFFQQVQPFFDNIFVAVWDPKQAIREGAVAALRACLILTTQREPKEMQKPQWYRHTFEEAEKGFDETLAKEKGMNRDDRIHGALLILNELVRISSMEGERLREEMEEITQQQLVHDKYCKDLMGFGTKPRHITPFTSFQAVQPQQSNALVGLLGYSSHQGLMGFGTSPSPAKSTLVESRCCRDLMEEKFDQVCQWVLKCRNSKNSLIQMTILNLLPRLAAFRPSAFTDTQYLQDTMNHVLSCVKKEKERTAAFQALGLLSVAVRSEFKVYLPRVLDIIRAALPPKDFAHKRQKAMQVDATVFTCISMLARAMGPGIQQDIKELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLLKMLSLVLMHKPLRHPGMPKGLAHQLASPGLTTLPEASDVGSITLALRTLGSFEFEGHSLTQFVRHCADHFLNSEHKEIRMEAARTCSRLLTPSIHLISGHAHVVSQTAVQVVADVLSKLLVVGITDPDPDIRYCVLASLDERFDAHLAQAENLQALFVALNDQVFEIRELAICTVGRLSSMNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSARMLGHLVSNAPRLIRPYMEPILKALILKLKDPDPDPNPGVINNVLATIGELAQVSGLEMRKWVDELFIIIMDMLQDSSLLAKRQVALWTLGQLVASTGYVVEPYRKYPTLLEVLLNFLKTEQNQGTRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSLSESKSSQDSSDYSTSEMLVNMGNLPLDEFYPAVSMVALMRIFRDQSLSHHHTMVVQAITFIFKSLGLKCVQFLPQVMPTFLNVIRVCDGAIREFLFQQLGMLVSFVKSHIRPYMDEIVTLMREFWVMNTSIQSTIILLIEQIVVALGGEFKLYLPQLIPHMLRVFMHDNSPGRIVSIKLLAAIQLFGANLDDYLHLLLPPIVKLFDAPEAPLPSRKAALETVDRLTESLDFTDYASRIIHPIVRTLDQSPELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVLVRHRINHQRYDVLICRIVKGYTLADEEEDPLIYQHRMLRSGQGDALASGPVETGPMKKLHVSTINLQKAWGAARRVSKDDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNAAFVSCWSELNEDQQDELIRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKALHYKELEFQKGPTPAILESLISINNKLQQPEAAAGVLEYAMKHFGELEIQATWYEKLHEWEDALVAYDKKMDTNKDDPELMLGRMRCLEALGEWGQLHQQCCEKWTLVNDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYKLVPERREIIRQIWWERLQGCQRIVEDWQKILMVRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSRQLDHPLPTVHPQVTYAYMKNMWKSARKIDAFQHMQHFVQTMQQQAQHAIATEDQQHKQELHKLMARCFLKLGEWQLNLQGINESTIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEAVLHYKHQNQARDEKKKLRHASGANITNATTAATTAATATTTASTEGSNSESEAESTENSPTPSPLQKKVTEDLSKTLLMYTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYSAGQSVEILDGVELGEPAHKKTGTTVPESIHSFIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVELLIKQATSHENLCQCYIGWCPFW 显示更多

同源基因和蛋白信息

同源种属	基因编号（Gene ID）	基因名称（Gene Symbol)	蛋白名称	种属编号（Tax ID)	其它基因编号（Gene ID）	来源
Chimp	457945	MTOR	mechanistic target of rapamycin kinase	9598	VGNC:8416	OMA, EggNOG
Macaque	106992736	MTOR	mechanistic target of rapamycin kinase	9544		OMA, EggNOG
Mouse	56717	Mtor	mechanistic target of rapamycin kinase	10090	MGI:1928394	Inparanoid, OMA, EggNOG
Rat	56718	Mtor	mechanistic target of rapamycin kinase	10116	RGD:68371	Inparanoid, OMA, EggNOG
Dog	478232	MTOR	mechanistic target of rapamycin kinase	9615	VGNC:43490	Inparanoid, OMA, EggNOG
Horse	100051341	MTOR	mechanistic target of rapamycin kinase	9796	VGNC:20434	Inparanoid, OMA, EggNOG
Cow	100139219	MTOR	mechanistic target of rapamycin kinase	9913	VGNC:31748	Inparanoid, OMA, EggNOG
Pig	100127359	MTOR	mechanistic target of rapamycin kinase	9823		Inparanoid, OMA, EggNOG
Opossum	100619675	MTOR	mechanistic target of rapamycin kinase	13616		Inparanoid, OMA, EggNOG
Chicken	419455	MTOR	mechanistic target of rapamycin	9031	CGNC:2430	Inparanoid, OMA, EggNOG
Anole lizard	100565267	mtor	mechanistic target of rapamycin kinase	28377		Inparanoid, OMA, EggNOG
Xenopus		XB-GENE-994583	Putative ortholog of fKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (MTOR), 1 of 2 [Source:Xenbase;Acc:XB-GENE-994583]	8364		OMA, EggNOG
Zebrafish	324254	mtor	mechanistic target of rapamycin kinase	7955	ZDB-GENE-030131-2974	Inparanoid, OMA, EggNOG
C. elegans	172167	let-363	Target of rapamycin homolog	6239		Inparanoid, OMA
Fruitfly	47396	Tor	Target of rapamycin	7227	FBgn0021796	Inparanoid, EggNOG
S.cerevisiae	853632	TOR2	phosphatidylinositol kinase-related protein kinase TOR2	4932	S000001686	Inparanoid, OMA
S.cerevisiae	853529	TOR1	phosphatidylinositol kinase-related protein kinase TOR1	4932	S000003827	OMA, EggNOG

蛋白质类别

PANTHER Classes
蛋白质    /    non-receptor serine/threonine protein kinase    /    丝氨酸/苏氨酸蛋白激酶mtor
蛋白质    /    protein kinase    /    丝氨酸/苏氨酸蛋白激酶mtor
蛋白质    /    nucleotide kinase    /    丝氨酸/苏氨酸蛋白激酶mtor
蛋白质    /    transferase    /    丝氨酸/苏氨酸蛋白激酶mtor
蛋白质    /    kinase    /    丝氨酸/苏氨酸蛋白激酶mtor
蛋白质    /    nucleic acid binding    /    丝氨酸/苏氨酸蛋白激酶mtor

DTO Classes
蛋白质 / 激酶 / 蛋白激酶 / 非典型组 / PIKK 家族 / FRAP亚家族 / 丝氨酸/苏氨酸蛋白激酶mtor

Associated Approved Drugs

引用文献

MTOR

基因和蛋白信息

蛋白质类别

相关重组蛋白

相关抗体

Associated Approved Drugs

相关活性配体

相关疾病

引用文献

MTOR

基因和蛋白信息

蛋白质类别

相关重组蛋白

相关抗体

相关活性小分子

Associated Approved Drugs

相关活性配体

相关疾病

引用文献