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| 描述 | 钠通道蛋白 5 型亚基 α |
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基因和蛋白信息
| 基因ID | 6331 |
|---|---|
| Uniprot Accession IDs | Q14524 A5H1P8 A6N922 A6N923 B2RTU0 E7ET19 E9PEF3 E9PEK2 E9PFW7 Q59H93 Q75RX9 Q75RY0 Q86UR3 Q8IZC9 Q96J69 |
| Ensembl ID | ENSG00000183873 |
| 原子符号 | HB1 HB2 HH1 IVF VF1 HBBD ICCD LQT3 SSS1 CDCD2 CMD1E CMPD2 PFHB1 Nav1.5 |
| Chromosome | 3 |
| 家族 | Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.5/SCN5A subfamily. |
| 序列 |
MANFLLPRGTSSFRRFTRESLAAIEKRMAEKQARGSTTLQESREGLPEEEAPRPQLDLQASKKLPDLYGNPPQELIGEPLEDLDPFYSTQKTFIVLNKGKTIFRFSATNALYVLSPFHPIRRAAVKILVHSLFNMLIMCTILTNCVFMAQHDPPPWTKYVEYTFTAIYTFESLVKILARGFCLHAFTFLRDPWNWLDFSVIIMAYTTEFVDLGNVSALRTFRVLRALKTISVISGLKTIVGALIQSVKKLADVMVLTVFCLSVFALIGLQLFMGNLRHKCVRNFTALNGTNGSVEADGLVWESLDLYLSDPENYLLKNGTSDVLLCGNSSDAGTCPEGYRCLKAGENPDHGYTSFDSFAWAFLALFRLMTQDCWERLYQQTLRSAGKIYMIFFMLVIFLGSFYLVNLILAVVAMAYEEQNQATIAETEEKEKRFQEAMEMLKKEHEALTIRGVDTVSRSSLEMSPLAPVNSHERRSKRRKRMSSGTEECGEDRLPKSDSEDGPRAMNHLSLTRGLSRTSMKPRSSRGSIFTFRRRDLGSEADFADDENSTAGESESHHTSLLVPWPLRRTSAQGQPSPGTSAPGHALHGKKNSTVDCNGVVSLLGAGDPEATSPGSHLLRPVMLEHPPDTTTPSEEPGGPQMLTSQAPCVDGFEEPGARQRALSAVSVLTSALEELEESRHKCPPCWNRLAQRYLIWECCPLWMSIKQGVKLVVMDPFTDLTITMCIVLNTLFMALEHYNMTSEFEEMLQVGNLVFTGIFTAEMTFKIIALDPYYYFQQGWNIFDSIIVILSLMELGLSRMSNLSVLRSFRLLRVFKLAKSWPTLNTLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKNYSELRDSDSGLLPRWHMMDFFHAFLIIFRILCGEWIETMWDCMEVSGQSLCLLVFLLVMVIGNLVVLNLFLALLLSSFSADNLTAPDEDREMNNLQLALARIQRGLRFVKRTTWDFCCGLLRQRPQKPAALAAQGQLPSCIATPYSPPPPETEKVPPTRKETRFEEGEQPGQGTPGDPEPVCVPIAVAESDTDDQEEDEENSLGTEEESSKQQESQPVSGGPEAPPDSRTWSQVSATASSEAEASASQADWRQQWKAEPQAPGCGETPEDSCSEGSTADMTNTAELLEQIPDLGQDVKDPEDCFTEGCVRRCPCCAVDTTQAPGKVWWRLRKTCYHIVEHSWFETFIIFMILLSSGALAFEDIYLEERKTIKVLLEYADKMFTYVFVLEMLLKWVAYGFKKYFTNAWCWLDFLIVDVSLVSLVANTLGFAEMGPIKSLRTLRALRPLRALSRFEGMRVVVNALVGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFGRCINQTEGDLPLNYTIVNNKSQCESLNLTGELYWTKVKVNFDNVGAGYLALLQVATFKGWMDIMYAAVDSRGYEEQPQWEYNLYMYIYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKLGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLNKYQGFIFDIVTKQAFDVTIMFLICLNMVTMMVETDDQSPEKINILAKINLLFVAIFTGECIVKLAALRHYYFTNSWNIFDFVVVILSIVGTVLSDIIQKYFFSPTLFRVIRLARIGRILRLIRGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYSIFGMANFAYVKWEAGIDDMFNFQTFANSMLCLFQITTSAGWDGLLSPILNTGPPYCDPTLPNSNGSRGDCGSPAVGILFFTTYIIISFLIVVNMYIAIILENFSVATEESTEPLSEDDFDMFYEIWEKFDPEATQFIEYSVLSDFADALSEPLRIAKPNQISLINMDLPMVSGDRIHCMDILFAFTKRVLGESGEMDALKIQMEEKFMAANPSKISYEPITTTLRRKHEEVSAMVIQRAFRRHLLQRSLKHASFLFRQQAGSGLSEEDAPEREGLIAYVMSENFSRPLGPPSSSSISSTSFPPSYDSVTRATSDNLQVRGSDYSHSEDLADFPPSPDRDRESIV
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同源基因和蛋白信息
| 同源种属 | 基因编号（Gene ID） | 基因名称（Gene Symbol) | 蛋白名称 | 种属编号（Tax ID) | 其它基因编号（Gene ID） | 来源 |
|---|---|---|---|---|---|---|
| Chimp | 747523 | SCN5A | sodium voltage-gated channel alpha subunit 5 | 9598 | VGNC:12183 | OMA, EggNOG |
| Macaque | 695085 | SCN5A | sodium voltage-gated channel alpha subunit 5 | 9544 | OMA, EggNOG | |
| Mouse | 20271 | Scn5a | sodium channel, voltage-gated, type V, alpha | 10090 | MGI:98251 | Inparanoid, OMA, EggNOG |
| Rat | 25665 | Scn5a | sodium voltage-gated channel alpha subunit 5 | 10116 | RGD:3637 | Inparanoid, OMA, EggNOG |
| Dog | 403497 | SCN5A | sodium voltage-gated channel alpha subunit 5 | 9615 | VGNC:45921 | Inparanoid, OMA, EggNOG |
| Horse | 100034027 | SCN5A | sodium voltage-gated channel alpha subunit 5 | 9796 | VGNC:22740 | Inparanoid, OMA, EggNOG |
| Cow | 282061 | SCN5A | sodium voltage-gated channel alpha subunit 5 | 9913 | VGNC:34352 | Inparanoid, OMA, EggNOG |
| Pig | 100152567 | SCN5A | sodium voltage-gated channel alpha subunit 5 | 9823 | OMA, EggNOG | |
| Opossum | 100653514 | SCN5A | sodium voltage-gated channel alpha subunit 5 | 13616 | Inparanoid, OMA, EggNOG | |
| Chicken | 395947 | SCN5A | sodium voltage-gated channel alpha subunit 5 | 9031 | CGNC:49568 | Inparanoid, OMA |
蛋白质类别
PANTHER Classes
蛋白质 / transporter / calcium channel / 钠通道蛋白 5 型亚基 α
蛋白质 / transporter / voltage-gated sodium channel / 钠通道蛋白 5 型亚基 α
蛋白质 / transporter / voltage-gated calcium channel / 钠通道蛋白 5 型亚基 α
蛋白质 / transporter / sodium channel / 钠通道蛋白 5 型亚基 α
蛋白质 / transporter / voltage-gated ion channel / 钠通道蛋白 5 型亚基 α
蛋白质 / transporter / calcium channel / 钠通道蛋白 5 型亚基 α
蛋白质 / transporter / voltage-gated sodium channel / 钠通道蛋白 5 型亚基 α
蛋白质 / transporter / voltage-gated calcium channel / 钠通道蛋白 5 型亚基 α
蛋白质 / transporter / sodium channel / 钠通道蛋白 5 型亚基 α
蛋白质 / transporter / voltage-gated ion channel / 钠通道蛋白 5 型亚基 α
相关重组蛋白
| 蛋白名称 | 规格与纯度 | 表达系统 | 蛋白标签 | 是否现货 | 查看详情 |
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相关抗体
| 名称 | 规格与纯度 | 种属反应性 | 应用 | 是否现货 | 查看详情 |
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Associated Approved Drugs
相关活性配体
相关疾病
| 疾病英文名称 | 疾病中文名称 | 疾病类型 | Mondoid | Direct Associated Targets |
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