SCN8A

描述	钠通道蛋白 8 型亚基 α

基因和蛋白信息

基因ID	6334
Uniprot Accession IDs	Q9UQD0 B9VWG8 O95788 Q9NYX2 Q9UPB2
Ensembl ID	ENSG00000196876
原子符号	MED MED PN4 CIAT BFIS5 NaCh6 CERIII EIEE13 MYOCL2 Nav1.6
Chromosome	12
家族	Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.6/SCN8A subfamily.
序列	MAARLLAPPGPDSFKPFTPESLANIERRIAESKLKKPPKADGSHREDDEDSKPKPNSDLEAGKSLPFIYGDIPQGLVAVPLEDFDPYYLTQKTFVVLNRGKTLFRFSATPALYILSPFNLIRRIAIKILIHSVFSMIIMCTILTNCVFMTFSNPPDWSKNVEYTFTGIYTFESLVKIIARGFCIDGFTFLRDPWNWLDFSVIMMAYITEFVNLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNKCVVWPINFNESYLENGTKGFDWEEYINNKTNFYTVPGMLEPLLCGNSSDAGQCPEGYQCMKAGRNPNYGYTSFDTFSWAFLALFRLMTQDYWENLYQLTLRAAGKTYMIFFVLVIFVGSFYLVNLILAVVAMAYEEQNQATLEEAEQKEAEFKAMLEQLKKQQEEAQAAAMATSAGTVSEDAIEEEGEEGGGSPRSSSEISKLSSKSAKERRNRRKKRKQKELSEGEEKGDPEKVFKSESEDGMRRKAFRLPDNRIGRKFSIMNQSLLSIPGSPFLSRHNSKSSIFSFRGPGRFRDPGSENEFADDEHSTVEESEGRRDSLFIPIRARERRSSYSGYSGYSQGSRSSRIFPSLRRSVKRNSTVDCNGVVSLIGGPGSHIGGRLLPEATTEVEIKKKGPGSLLVSMDQLASYGRKDRINSIMSVVTNTLVEELEESQRKCPPCWYKFANTFLIWECHPYWIKLKEIVNLIVMDPFVDLAITICIVLNTLFMAMEHHPMTPQFEHVLAVGNLVFTGIFTAEMFLKLIAMDPYYYFQEGWNIFDGFIVSLSLMELSLADVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKINQDCELPRWHMHDFFHSFLIVFRVLCGEWIETMWDCMEVAGQAMCLIVFMMVMVIGNLVVLNLFLALLLSSFSADNLAATDDDGEMNNLQISVIRIKKGVAWTKLKVHAFMQAHFKQREADEVKPLDELYEKKANCIANHTGADIHRNGDFQKNGNGTTSGIGSSVEKYIIDEDHMSFINNPNLTVRVPIAVGESDFENLNTEDVSSESDPEGSKDKLDDTSSSEGSTIDIKPEVEEVPVEQPEEYLDPDACFTEGCVQRFKCCQVNIEEGLGKSWWILRKTCFLIVEHNWFETFIIFMILLSSGALAFEDIYIEQRKTIRTILEYADKVFTYIFILEMLLKWTAYGFVKFFTNAWCWLDFLIVAVSLVSLIANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALVGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKYHYCFNETSEIRFEIEDVNNKTECEKLMEGNNTEIRWKNVKINFDNVGAGYLALLQVATFKGWMDIMYAAVDSRKPDEQPKYEDNIYMYIYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLNKIQGIVFDFVTQQAFDIVIMMLICLNMVTMMVETDTQSKQMENILYWINLVFVIFFTCECVLKMFALRHYYFTIGWNIFDFVVVILSIVGMFLADIIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIFSIFGMSNFAYVKHEAGIDDMFNFETFGNSMICLFQITTSAGWDGLLLPILNRPPDCSLDKEHPGSGFKGDCGNPSVGIFFFVSYIIISFLIVVNMYIAIILENFSVATEESADPLSEDDFETFYEIWEKFDPDATQFIEYCKLADFADALEHPLRVPKPNTIELIAMDLPMVSGDRIHCLDILFAFTKRVLGDSGELDILRQQMEERFVASNPSKVSYEPITTTLRRKQEEVSAVVLQRAYRGHLARRGFICKKTTSNKLENGGTHREKKESTPSTASLPSYDSVTKPEKEKQQRAEEGRRERAKRQKEVRESKC 显示更多

同源基因和蛋白信息

同源种属	基因编号（Gene ID）	基因名称（Gene Symbol)	蛋白名称	种属编号（Tax ID)	其它基因编号（Gene ID）	来源
Macaque	695972	SCN8A	sodium voltage-gated channel alpha subunit 8	9544		Inparanoid, OMA, EggNOG
Mouse	20273	Scn8a	sodium channel, voltage-gated, type VIII, alpha	10090	MGI:103169	Inparanoid, OMA, EggNOG
Rat	29710	Scn8a	sodium voltage-gated channel alpha subunit 8	10116	RGD:3638	Inparanoid, OMA, EggNOG
Dog	477604	SCN8A	sodium voltage-gated channel alpha subunit 8	9615	VGNC:45923	Inparanoid, OMA
Horse	100052777	SCN8A	sodium voltage-gated channel alpha subunit 8	9796	VGNC:22742	Inparanoid, OMA
Cow	537277	SCN8A	sodium voltage-gated channel alpha subunit 8	9913	VGNC:34354	Inparanoid, OMA
Anole lizard	100556690	scn8a	sodium voltage-gated channel alpha subunit 8	28377		Inparanoid, OMA
Xenopus	549640	scn8a	sodium channel, voltage gated, type VIII alpha subunit	8364	XB-GENE-1011299	Inparanoid, OMA
Zebrafish	58152	scn8aa	sodium channel, voltage gated, type VIII, alpha subunit a	7955	ZDB-GENE-000828-1	Inparanoid, OMA

蛋白质类别

PANTHER Classes
蛋白质    /    transporter    /    calcium channel    /    钠通道蛋白 8 型亚基 α
蛋白质    /    transporter    /    voltage-gated sodium channel    /    钠通道蛋白 8 型亚基 α
蛋白质    /    transporter    /    voltage-gated calcium channel    /    钠通道蛋白 8 型亚基 α
蛋白质    /    transporter    /    sodium channel    /    钠通道蛋白 8 型亚基 α
蛋白质    /    transporter    /    voltage-gated ion channel    /    钠通道蛋白 8 型亚基 α

DTO Classes
蛋白质 / 离子通道 / 钠通道家族 / Nav1.6/SCN8A 亚家族 / 钠通道蛋白 8 型亚基 α

Associated Approved Drugs

引用文献

SCN8A

基因和蛋白信息

蛋白质类别

相关重组蛋白

相关抗体

Associated Approved Drugs

相关活性配体

相关疾病

引用文献

SCN8A

基因和蛋白信息

蛋白质类别

相关重组蛋白

相关抗体

相关活性小分子

Associated Approved Drugs

相关活性配体

相关疾病

引用文献