SIRT1

描述	NAD 依赖性蛋白去乙酰化酶 sirtuin-1

基因和蛋白信息

基因ID	23411
Uniprot Accession IDs	Q96EB6 Q2XNF6 Q5JVQ0 Q9GZR9 Q9Y6F0 hSIRT1
Ensembl ID	ENSG00000096717
原子符号	SIR2L1 SIR2 SIR2L1 SIR2alpha
Chromosome	10
家族	Belongs to the sirtuin family. Class I subfamily.
序列	MADEAALALQPGGSPSAAGADREAASSPAGEPLRKRPRRDGPGLERSPGEPGGAAPEREVPAAARGCPGAAAAALWREAEAEAAAAGGEQEAQATAAAGEGDNGPGLQGPSREPPLADNLYDEDDDDEGEEEEEAAAAAIGYRDNLLFGDEIITNGFHSCESDEEDRASHASSSDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLCCNPVKLSEITEKPPRTQKELAYLSELPPTPLHVSEDSSSPERTSPPDSSVIVTLLDQAAKSNDDLDVSESKGCMEEKPQEVQTSRNVESIAEQMENPDLKNVGSSTGEKNERTSVAGTVRKCWPNRVAKEQISRRLDGNQYLFLPPNRYIFHGAEVYSDSEDDVLSSSSCGSNSDSGTCQSPSLEEPMEDESEIEEFYNGLEDEPDVPERAGGAGFGTDGDDQEAINEAISVKQEVTDMNYPSNKS 显示更多

同源基因和蛋白信息

同源种属	基因编号（Gene ID）	基因名称（Gene Symbol)	蛋白名称	种属编号（Tax ID)	其它基因编号（Gene ID）	来源
Chimp	107966703	SIRT1	sirtuin 1	9598	VGNC:12502	OMA, EggNOG
Macaque	695682	SIRT1	sirtuin 1	9544		OMA, EggNOG
Mouse	93759	Sirt1	sirtuin 1	10090	MGI:2135607	Inparanoid, OMA, EggNOG
Dog	489012	SIRT1	sirtuin 1	9615	VGNC:46183	Inparanoid, OMA, EggNOG
Horse	100072571	SIRT1	sirtuin 1	9796	VGNC:51676	Inparanoid, OMA, EggNOG
Cow	613629	SIRT1	sirtuin 1	9913	VGNC:34630	Inparanoid, OMA, EggNOG
Pig	751859	SIRT1	sirtuin 1	9823		Inparanoid, OMA, EggNOG
Opossum	100015574	SIRT1	sirtuin 1	13616		Inparanoid, EggNOG
Chicken	423646	SIRT1	sirtuin 1	9031	CGNC:52016	Inparanoid, OMA, EggNOG
Anole lizard	100564010	sirt1	sirtuin 1	28377		Inparanoid, OMA, EggNOG
Xenopus	100145679	sirt1	sirtuin 1	8364	XB-GENE-989003	Inparanoid, OMA, EggNOG
Zebrafish	797132	sirt1	sirtuin 1	7955	ZDB-GENE-070801-2	Inparanoid, OMA, EggNOG
Fruitfly	34708	Sirt1	Sirtuin 1	7227	FBgn0024291	Inparanoid, EggNOG

蛋白质类别

PANTHER Classes
蛋白质 / hydrolase / deacetylase / NAD 依赖性蛋白去乙酰化酶 sirtuin-1
蛋白质 / hydrolase / chromatin/chromatin-binding protein / NAD 依赖性蛋白去乙酰化酶 sirtuin-1

DTO Classes
蛋白质 / 表观遗传调控因子 / 橡皮 / 组蛋白去乙酰化酶 / 组蛋白去乙酰化酶III类 / NAD 依赖性蛋白去乙酰化酶 sirtuin-1