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| 描述 | 受体酪氨酸蛋白激酶 erbB-2 |
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基因和蛋白信息
| 基因ID | 2064 |
|---|---|
| Uniprot Accession IDs | P04626 B2RZG3 B4DHN3 Q14256 Q6LDV1 Q9UMK4 X5D2V5 |
| Ensembl ID | ENSG00000141736 |
| 原子符号 | HER2 MLN19 NEU NGL NEU NGL HER2 TKR1 CD340 HER-2 MLN 19 HER-2/neu |
| Chromosome | 17 |
| 家族 | Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily. |
| 序列 |
MELAALCRWGLLLALLPPGAASTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSEDCQSLTRTVCAGGCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSANIQEFAGCKKIFGSLAFLPESFDGDPASNTAPLQPEQLQVFETLEEITGYLYISAWPDSLPDLSVFQNLQVIRGRILHNGAYSLTLQGLGISWLGLRSLRELGSGLALIHHNTHLCFVHTVPWDQLFRNPHQALLHTANRPEDECVGEGLACHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVNARHCLPCHPECQPQNGSVTCFGPEADQCVACAHYKDPPFCVARCPSGVKPDLSYMPIWKFPDEEGACQPCPINCTHSCVDLDDKGCPAEQRASPLTSIISAVVGILLVVVLGVVFGILIKRRQQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFCPDPAPGAGGMVHHRHRSSSTRSGGGDLTLGLEPSEEEAPRSPLAPSEGAGSDVFDGDLGMGAAKGLQSLPTHDPSPLQRYSEDPTVPLPSETDGYVAPLTCSPQPEYVNQPDVRPQPPSPREGPLPAARPAGATLERPKTLSPGKNGVVKDVFAFGGAVENPEYLTPQGGAAPQPHPPPAFSPAFDNLYYWDQDPPERGAPPSTFKGTPTAENPEYLGLDVPV
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同源基因和蛋白信息
| 同源种属 | 基因编号（Gene ID） | 基因名称（Gene Symbol) | 蛋白名称 | 种属编号（Tax ID) | 其它基因编号（Gene ID） | 来源 |
|---|---|---|---|---|---|---|
| Chimp | 454636 | ERBB2 | erb-b2 receptor tyrosine kinase 2 | 9598 | VGNC:9276 | OMA, EggNOG |
| Macaque | 697573 | ERBB2 | erb-b2 receptor tyrosine kinase 2 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 13866 | Erbb2 | erb-b2 receptor tyrosine kinase 2 | 10090 | MGI:95410 | Inparanoid, OMA, EggNOG |
| Rat | 24337 | Erbb2 | erb-b2 receptor tyrosine kinase 2 | 10116 | RGD:2561 | Inparanoid, OMA, EggNOG |
| Dog | 403883 | ERBB2 | erb-b2 receptor tyrosine kinase 2 | 9615 | VGNC:40436 | Inparanoid, OMA, EggNOG |
| Horse | 100054739 | ERBB2 | erb-b2 receptor tyrosine kinase 2 | 9796 | VGNC:17649 | Inparanoid, OMA, EggNOG |
| Cow | 505709 | ERBB2 | erb-b2 receptor tyrosine kinase 2 | 9913 | VGNC:28563 | OMA, EggNOG |
| Pig | 100516641 | ERBB2 | erb-b2 receptor tyrosine kinase 2 | 9823 | OMA, EggNOG | |
| Opossum | 100017172 | ERBB2 | erb-b2 receptor tyrosine kinase 2 | 13616 | Inparanoid, OMA, EggNOG | |
| Anole lizard | 100565910 | erbb2 | erb-b2 receptor tyrosine kinase 2 | 28377 | Inparanoid, OMA | |
| Zebrafish | 386966 | erbb2 | erb-b2 receptor tyrosine kinase 2 | 7955 | ZDB-GENE-031118-121 | Inparanoid, OMA |
相关重组蛋白
| 蛋白名称 | 规格与纯度 | 表达系统 | 蛋白标签 | 是否现货 | 查看详情 |
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相关抗体
| 名称 | 规格与纯度 | 种属反应性 | 应用 | 是否现货 | 查看详情 |
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Associated Approved Drugs
相关活性配体
相关疾病
| 疾病英文名称 | 疾病中文名称 | 疾病类型 | Mondoid | Direct Associated Targets |
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