吡唑基吡啶

描述:

含吡唑吡啶骨架的化合物，其结构为吡唑通过键与吡啶连接（非共环）。

上级分类:

有机化合物 ⮕ 有机杂环化合物 ⮕ 吡啶及其衍生物 ⮕ 吡唑基吡啶

热门产品

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5-氨基-1-(2-吡啶基)-1H-吡唑-4-甲腈
CAS: 72816-14-9 EC号: 979-035-7 分子式: C₉H₇N₅ 分子量: 185.19

≥97%

有现货货号: A177297

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技术标识符

IUPAC名称

5-amino-1-pyridin-2-ylpyrazole-4-carbonitrile

SMILES

C1=CC=NC(=C1)N2C(=C(C=N2)C#N)N

InChIKey

GFILBPUBXBGRHW-UHFFFAOYSA-N

InChI

1S/C9H7N5/c10-5-7-6-13-14(9(7)11)8-3-1-2-4-12-8/h1-4,6H,11H2
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2-(1-吡唑基)吡啶
CAS: 25700-11-2 化合物 CID: 5324086 分子式: C₈H₇N₃ 分子量: 145.17

≥98%(GC)

有现货货号: P160634

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价格与包装

技术标识符

IUPAC名称

2-pyrazol-1-ylpyridine

SMILES

C1=CC=NC(=C1)N2C=CC=N2

InChIKey

XXTPHXNBKRVYJI-UHFFFAOYSA-N

InChI

1S/C8H7N3/c1-2-5-9-8(4-1)11-7-3-6-10-11/h1-7H
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2,6-二(1-吡唑基)吡啶
CAS: 123640-38-0 EC号: 808-081-1 分子式: C₁₁H₉N₅ 分子量: 211.23

≥98%(HPLC)

有现货货号: D155573

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价格与包装

技术标识符

IUPAC名称

2,6-di(pyrazol-1-yl)pyridine

SMILES

C1=CC(=NC(=C1)N2C=CC=N2)N3C=CC=N3

InChIKey

OMNFEFLKDQUMRN-UHFFFAOYSA-N

InChI

1S/C11H9N5/c1-4-10(15-8-2-6-12-15)14-11(5-1)16-9-3-7-13-16/h1-9H
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DCC-2618,Kit (c-Kit)和PDGFR抑制剂
CAS: 1225278-16-9 分子式: C₂₆H₂₁F₂N₅O₃ 分子量: 489.47

Moligand™ ? ≥98%

有现货货号: D126474

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价格与包装

技术标识符

IUPAC名称

1-N'-[2,5-difluoro-4-[2-(1-methylpyrazol-4-yl)pyridin-4-yl]oxyphenyl]-1-N-phenylcyclopropane-1,1-dicarboxamide

SMILES

CN1C=C(C=N1)C2=NC=CC(=C2)OC3=C(C=C(C(=C3)F)NC(=O)C4(CC4)C(=O)NC5=CC=CC=C5)F

InChIKey

WWOXKWLDMLMYQY-UHFFFAOYSA-N

InChI

1S/C26H21F2N5O3/c1-33-15-16(14-30-33)21-11-18(7-10-29-21)36-23-13-19(27)22(12-20(23)28)32-25(35)26(8-9-26)24(34)31-17-5-3-2-4-6-17/h2-7,10-15H,8-9H2,1H3,(H,31,34)(H,32,35)
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克唑替尼
CAS: 877399-52-5 EC号: 638-814-9 分子式: C₂₁H₂₂Cl₂FN₅O 分子量: 450.34

≥99%

有现货货号: C137735

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价格与包装

技术标识符

IUPAC名称

3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine

SMILES

CC(C1=C(C=CC(=C1Cl)F)Cl)OC2=C(N=CC(=C2)C3=CN(N=C3)C4CCNCC4)N

InChIKey

KTEIFNKAUNYNJU-GFCCVEGCSA-N

InChI

1S/C21H22Cl2FN5O/c1-12(19-16(22)2-3-17(24)20(19)23)30-18-8-13(9-27-21(18)25)14-10-28-29(11-14)15-4-6-26-7-5-15/h2-3,8-12,15,26H,4-7H2,1H3,(H2,25,27)/t12-/m1/s1

关联靶标

Ephrin type-B receptor 6, Macrophage-stimulating protein receptor, Proto-oncogene tyrosine-protein kinase ROS, Hepatocyte growth factor receptor, Tyrosine-protein kinase Mer, Angiopoietin-1 receptor, STE20-like serine/threonine-protein kinase, Leukocyte tyrosine kinase receptor, Tyrosine-protein kinase ABL1, ALK tyrosine kinase receptor, Tyrosine-protein kinase receptor UFO, BDNF/NT-3 growth factors receptor, Tyrosine-protein kinase JAK2
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氯虫酰胺
CAS: 500008-45-7 EC号: 610-489-8 分子式: C₁₈H₁₄BrCl₂N₅O₂ 分子量: 483.15

分析标准品 ? Moligand™ ?

有现货货号: C133725

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价格与包装

技术标识符

IUPAC名称

5-bromo-N-[4-chloro-2-methyl-6-(methylcarbamoyl)phenyl]-2-(3-chloropyridin-2-yl)pyrazole-3-carboxamide

SMILES

CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)Cl

InChIKey

PSOVNZZNOMJUBI-UHFFFAOYSA-N

InChI

1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)
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RepSox,TGF-β1型受体抑制剂
CAS: 446859-33-2 EC号: 663-924-9 分子式: C₁₇H₁₃N₅ 分子量: 287.32

≥98%

有现货货号: R125531

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价格与包装

技术标识符

IUPAC名称

2-[5-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]-1,5-naphthyridine

SMILES

CC1=NC(=CC=C1)C2=C(C=NN2)C3=NC4=C(C=C3)N=CC=C4

InChIKey

LBPKYPYHDKKRFS-UHFFFAOYSA-N

InChI

1S/C17H13N5/c1-11-4-2-5-16(20-11)17-12(10-19-22-17)13-7-8-14-15(21-13)6-3-9-18-14/h2-10H,1H3,(H,19,22)

关联靶标

TGF-beta receptor type-1
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PP121,酪氨酸和磷酸肌醇激酶的双重抑制剂
CAS: 1092788-83-4 EC号: 686-913-0 分子式: C₁₇H₁₇N₇ 分子量: 319.36

Moligand™ ? ≥98%

有现货货号: P126419

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价格与包装

技术标识符

IUPAC名称

1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)pyrazolo[3,4-d]pyrimidin-4-amine

SMILES

C1CCC(C1)N2C3=NC=NC(=C3C(=N2)C4=CN=C5C(=C4)C=CN5)N

InChIKey

NVRXTLZYXZNATH-UHFFFAOYSA-N

InChI

1S/C17H17N7/c18-15-13-14(11-7-10-5-6-19-16(10)20-8-11)23-24(12-3-1-2-4-12)17(13)22-9-21-15/h5-9,12H,1-4H2,(H,19,20)(H2,18,21,22)

关联靶标

Epidermal growth factor receptor, Proto-oncogene tyrosine-protein kinase receptor Ret, DNA-dependent protein kinase catalytic subunit, Proto-oncogene tyrosine-protein kinase Src, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Platelet-derived growth factor receptor alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, Vascular endothelial growth factor receptor 2, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase HCK, Serine/threonine-protein kinase mTOR
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6-(1H-吡唑-1-基)烟酸
CAS: 253315-22-9 分子式: C₉H₇N₃O₂ 分子量: 189.2

≥97%

有现货货号: P123110

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价格与包装

技术标识符

IUPAC名称

6-pyrazol-1-ylpyridine-3-carboxylic acid

SMILES

C1=CN(N=C1)C2=NC=C(C=C2)C(=O)O

InChIKey

QWFKXYLAKWFQLF-UHFFFAOYSA-N

InChI

1S/C9H7N3O2/c13-9(14)7-2-3-8(10-6-7)12-5-1-4-11-12/h1-6H,(H,13,14)
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MK-2461,多靶点抑制剂
CAS: 917879-39-1 分子式: C₂₄H₂₅N₅O₅S 分子量: 495.55

Moligand™ ? ≥98%

有现货货号: M129777

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价格与包装

技术标识符

IUPAC名称

14-[[[(2R)-1,4-dioxan-2-yl]methyl-methylsulfamoyl]amino]-5-(1-methylpyrazol-4-yl)-2-oxo-7-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,9,12,14-heptaene

SMILES

CN1C=C(C=N1)C2=CC3=C(C=CC4=C(C3=O)C=C(C=C4)NS(=O)(=O)N(C)CC5COCCO5)N=C2

InChIKey

JGEBLDKNWBUGRZ-HXUWFJFHSA-N

InChI

1S/C24H25N5O5S/c1-28-13-18(12-26-28)17-9-22-23(25-11-17)6-4-16-3-5-19(10-21(16)24(22)30)27-35(31,32)29(2)14-20-15-33-7-8-34-20/h3-6,9-13,20,27H,7-8,14-15H2,1-2H3/t20-/m1/s1

关联靶标

Macrophage-stimulating protein receptor, Vascular endothelial growth factor receptor 3, Receptor-type tyrosine-protein kinase FLT3, Fibroblast growth factor receptor 1, Fibroblast growth factor receptor 2, Fibroblast growth factor receptor 3, Hepatocyte growth factor receptor, Tyrosine-protein kinase Mer, Platelet-derived growth factor receptor beta, Vascular endothelial growth factor receptor 1, Vascular endothelial growth factor receptor 2, BDNF/NT-3 growth factors receptor, High affinity nerve growth factor receptor
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MK-8033
CAS: 1001917-37-8 分子式: C₂₅H₂₁N₅O₃S 分子量: 471.53

期货货号: M127968

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价格与包装

技术标识符

IUPAC名称

1-[5-(1-methylpyrazol-4-yl)-2-oxo-7-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,9,12,14-heptaen-14-yl]-N-(pyridin-2-ylmethyl)methanesulfonamide

SMILES

CN1C=C(C=N1)C2=CC3=C(C=CC4=C(C3=O)C=C(C=C4)CS(=O)(=O)NCC5=CC=CC=N5)N=C2

InChIKey

VMJFTOSOFDEKTM-UHFFFAOYSA-N

InChI

1S/C25H21N5O3S/c1-30-15-20(13-28-30)19-11-23-24(27-12-19)8-7-18-6-5-17(10-22(18)25(23)31)16-34(32,33)29-14-21-4-2-3-9-26-21/h2-13,15,29H,14,16H2,1H3

关联靶标

Macrophage-stimulating protein receptor, Hepatocyte growth factor receptor
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阿尔韦莱司他
CAS: 848141-11-7 分子式: C₂₅H₂₂F₃N₅O₄S 分子量: 545.53

Moligand™ ? ≥98%

有现货货号: A127407

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价格与包装

技术标识符

IUPAC名称

6-methyl-5-(2-methylpyrazol-3-yl)-N-[(5-methylsulfonylpyridin-2-yl)methyl]-2-oxo-1-[3-(trifluoromethyl)phenyl]pyridine-3-carboxamide

SMILES

CC1=C(C=C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)C(=O)NCC3=NC=C(C=C3)S(=O)(=O)C)C4=CC=NN4C

InChIKey

QNQZWEGMKJBHEM-UHFFFAOYSA-N

InChI

1S/C25H22F3N5O4S/c1-15-20(22-9-10-31-32(22)2)12-21(23(34)30-13-17-7-8-19(14-29-17)38(3,36)37)24(35)33(15)18-6-4-5-16(11-18)25(26,27)28/h4-12,14H,13H2,1-3H3,(H,30,34)

关联靶标

Neutrophil elastase