噻吩并嘧啶类

描述:

含噻吩环与嘧啶环并联的杂环化合物。噻吩为含四个碳原子和一个硫原子的五元环；嘧啶为含四个碳原子及1-位与3-位两个氮原子的六元环。

上级分类:

有机化合物 ⮕ 有机杂环化合物 ⮕ 噻吩并嘧啶类

产品列表

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T-26c
CAS: 869296-13-9 化合物 CID: 11525848 分子式: C₂₄H₂₁N₃O₆S 分子量: 479.51

10mM in DMSO

有现货货号: T426494

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价格与包装

技术标识符

IUPAC名称

4-[[2-[(3-methoxyphenyl)methylcarbamoyl]-4-oxo-3H-thieno[2,3-d]pyrimidin-5-yl]methoxymethyl]benzoic acid

SMILES

COC1=CC=CC(=C1)CNC(=O)C2=NC3=C(C(=CS3)COCC4=CC=C(C=C4)C(=O)O)C(=O)N2

InChIKey

CDQRIIUMNLMHRH-UHFFFAOYSA-N

InChI

1S/C24H21N3O6S/c1-32-18-4-2-3-15(9-18)10-25-22(29)20-26-21(28)19-17(13-34-23(19)27-20)12-33-11-14-5-7-16(8-6-14)24(30)31/h2-9,13H,10-12H2,1H3,(H,25,29)(H,30,31)(H,26,27,28)

关联靶标

Collagenase 3, Stromelysin-2, 72 kDa type IV collagenase, Stromelysin-1, Neutrophil collagenase
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TTP 22
CAS: 329907-28-0 化合物 CID: 1536915 分子式: C₁₆H₁₄N₂O₂S₂ 分子量: 330.42

10mM in DMSO

有现货货号: T423368

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价格与包装

技术标识符

IUPAC名称

3-[5-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]sulfanylpropanoic acid

SMILES

CC1=CC=C(C=C1)C2=CSC3=C2C(=NC=N3)SCCC(=O)O

InChIKey

RAOULLCLLOGTDA-UHFFFAOYSA-N

InChI

1S/C16H14N2O2S2/c1-10-2-4-11(5-3-10)12-8-22-16-14(12)15(17-9-18-16)21-7-6-13(19)20/h2-5,8-9H,6-7H2,1H3,(H,19,20)
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3,5,6,7-四氢-4H -环戊达[4,5] 硫代诺[2,3-d ]嘧啶-4 -酮
CAS: 14346-25-9 EC号: 674-827-6 化合物 CID: 203420 分子式: C₉H₈N₂OS 分子量: 192.24

10mM in DMSO

有现货货号: T421600

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价格与包装

技术标识符

IUPAC名称

7-thia-9,11-diazatricyclo[6.4.0.02,6]dodeca-1(8),2(6),9-trien-12-one

SMILES

C1CC2=C(C1)SC3=C2C(=O)NC=N3

InChIKey

MZAZSAHKQBGEMA-UHFFFAOYSA-N

InChI

1S/C9H8N2OS/c12-8-7-5-2-1-3-6(5)13-9(7)11-4-10-8/h4H,1-3H2,(H,10,11,12)
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PI-3065
CAS: 955977-50-1 化合物 CID: 24937012 分子式: C₂₇H₃₁FN₆OS 分子量: 506.64

Moligand™ ? 10mM in DMSO

有现货货号: P427071

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价格与包装

技术标识符

IUPAC名称

4-[6-[[4-(cyclopropylmethyl)piperazin-1-yl]methyl]-2-(5-fluoro-1H-indol-4-yl)thieno[3,2-d]pyrimidin-4-yl]morpholine

SMILES

C1CC1CN2CCN(CC2)CC3=CC4=C(S3)C(=NC(=N4)C5=C(C=CC6=C5C=CN6)F)N7CCOCC7

InChIKey

YDNOHCOYQVZOMC-UHFFFAOYSA-N

InChI

1S/C27H31FN6OS/c28-21-3-4-22-20(5-6-29-22)24(21)26-30-23-15-19(17-33-9-7-32(8-10-33)16-18-1-2-18)36-25(23)27(31-26)34-11-13-35-14-12-34/h3-6,15,18,29H,1-2,7-14,16-17H2

关联靶标

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
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PF-3758309
CAS: 898044-15-0 EC号: 804-641-4 化合物 CID: 25227462 分子式: C₂₅H₃₀N₈OS 分子量: 490.62

Moligand™ ? 10mM in DMSO

有现货货号: P426742

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价格与包装

技术标识符

IUPAC名称

N-[(1S)-2-(dimethylamino)-1-phenylethyl]-6,6-dimethyl-3-[(2-methylthieno[3,2-d]pyrimidin-4-yl)amino]-1,4-dihydropyrrolo[3,4-c]pyrazole-5-carboxamide

SMILES

CC1=NC2=C(C(=N1)NC3=NNC4=C3CN(C4(C)C)C(=O)NC(CN(C)C)C5=CC=CC=C5)SC=C2

InChIKey

AYCPARAPKDAOEN-LJQANCHMSA-N

InChI

1S/C25H30N8OS/c1-15-26-18-11-12-35-20(18)23(27-15)29-22-17-13-33(25(2,3)21(17)30-31-22)24(34)28-19(14-32(4)5)16-9-7-6-8-10-16/h6-12,19H,13-14H2,1-5H3,(H,28,34)(H2,26,27,29,30,31)/t19-/m1/s1

关联靶标

Cyclin-dependent kinase 7, General transcription and DNA repair factor IIH helicase subunit XPD, Cyclin-dependent kinase 17, Serine/threonine-protein kinase PAK 5, Serine/threonine-protein kinase 26, Ribosomal protein S6 kinase alpha-6, MAP/microtubule affinity-regulating kinase 4, 5'-AMP-activated protein kinase subunit gamma-1, 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit gamma-2, Dual specificity protein kinase CLK4, Serine/threonine-protein kinase PAK 4, Serine/threonine-protein kinase PAK 6, Serine/threonine-protein kinase PAK 1, Serine/threonine-protein kinase PAK 2, Serine/threonine-protein kinase PAK 3
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5-苯基噻吩并[2,3-d]嘧啶-4-硫醇
CAS: 182198-89-6 EC号: 832-111-2 化合物 CID: 718633 分子式: C₁₂H₈N₂S₂ 分子量: 244.34

10mM in DMSO

有现货货号: P422239

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价格与包装

技术标识符

IUPAC名称

5-phenyl-3H-thieno[2,3-d]pyrimidine-4-thione

SMILES

C1=CC=C(C=C1)C2=CSC3=C2C(=S)NC=N3

InChIKey

LNOFOMVIGAWPSJ-UHFFFAOYSA-N

InChI

1S/C12H8N2S2/c15-11-10-9(8-4-2-1-3-5-8)6-16-12(10)14-7-13-11/h1-7H,(H,13,14,15)
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7-甲基-5,6,7,8-四氢苯并[4,5]噻吩并[2,3-d]嘧啶-4-硫醇
CAS: 314260-78-1 分子式: C₁₁H₁₂N₂S₂ 分子量: 236.36

10mM in DMSO

期货货号: M423258

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价格与包装

技术标识符

IUPAC名称

7-methyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidine-4-thione

SMILES

CC1CCC2=C(C1)SC3=C2C(=S)NC=N3

InChIKey

RBWNDBNSJFCLBZ-UHFFFAOYSA-N

InChI

1S/C11H12N2S2/c1-6-2-3-7-8(4-6)15-11-9(7)10(14)12-5-13-11/h5-6H,2-4H2,1H3,(H,12,13,14)
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MI-463
CAS: 1628317-18-9 分子式: C₂₄H₂₃F₃N₆S 分子量: 484.54

10mM in DMSO

有现货货号: M421992

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价格与包装

技术标识符

IUPAC名称

4-methyl-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-1H-indole-2-carbonitrile

SMILES

CC1=C(C=CC2=C1C=C(N2)C#N)CN3CCC(CC3)NC4=C5C=C(SC5=NC=N4)CC(F)(F)F

InChIKey

DZACSLYTXLZAAF-UHFFFAOYSA-N

InChI

1S/C24H23F3N6S/c1-14-15(2-3-21-19(14)8-17(11-28)31-21)12-33-6-4-16(5-7-33)32-22-20-9-18(10-24(25,26)27)34-23(20)30-13-29-22/h2-3,8-9,13,16,31H,4-7,10,12H2,1H3,(H,29,30,32)

关联靶标

Menin
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MI-136
CAS: 1628316-74-4 分子式: C₂₃H₂₁F₃N₆S 分子量: 470.51

10mM in DMSO

有现货货号: M421991

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价格与包装

技术标识符

IUPAC名称

5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-1H-indole-2-carbonitrile

SMILES

C1CN(CCC1NC2=C3C=C(SC3=NC=N2)CC(F)(F)F)CC4=CC5=C(C=C4)NC(=C5)C#N

InChIKey

PSOJDGBGVBEYJX-UHFFFAOYSA-N

InChI

1S/C23H21F3N6S/c24-23(25,26)10-18-9-19-21(28-13-29-22(19)33-18)31-16-3-5-32(6-4-16)12-14-1-2-20-15(7-14)8-17(11-27)30-20/h1-2,7-9,13,16,30H,3-6,10,12H2,(H,28,29,31)

关联靶标

Menin
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IWP-2
CAS: 686770-61-6 分子式: C₂₂H₁₈N₄O₂S₃ 分子量: 466.6

2mM in DMSO

期货货号: I425479

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价格与包装

技术标识符

IUPAC名称

N-(6-methyl-1,3-benzothiazol-2-yl)-2-[(4-oxo-3-phenyl-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)sulfanyl]acetamide

SMILES

CC1=CC2=C(C=C1)N=C(S2)NC(=O)CSC3=NC4=C(C(=O)N3C5=CC=CC=C5)SCC4

InChIKey

WRKPZSMRWPJJDH-UHFFFAOYSA-N

InChI

1S/C22H18N4O2S3/c1-13-7-8-15-17(11-13)31-21(23-15)25-18(27)12-30-22-24-16-9-10-29-19(16)20(28)26(22)14-5-3-2-4-6-14/h2-8,11H,9-10,12H2,1H3,(H,23,25,27)

关联靶标

Protein-serine O-palmitoleoyltransferase porcupine
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GI-570482
CAS: 109164-47-8 分子式: C₁₃H₁₄N₂O₃S 分子量: 278.32

10mM in DMSO

期货货号: G420558

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价格与包装

技术标识符

IUPAC名称

3-(4-oxo-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-2-yl)propanoic acid

SMILES

C1CCC2=C(C1)C3=C(S2)N=C(NC3=O)CCC(=O)O

InChIKey

ZUYIZUTYDFCUMM-UHFFFAOYSA-N

InChI

1S/C13H14N2O3S/c16-10(17)6-5-9-14-12(18)11-7-3-1-2-4-8(7)19-13(11)15-9/h1-6H2,(H,16,17)(H,14,15,18)
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GNE-493
CAS: 1033735-94-2 分子式: C₁₇H₂₀N₆O₂S 分子量: 372.45

10mM in DMSO

有现货货号: G420415

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价格与包装

技术标识符

IUPAC名称

2-[2-(2-aminopyrimidin-5-yl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl]propan-2-ol

SMILES

CC(C)(C1=CC2=C(S1)C(=NC(=N2)C3=CN=C(N=C3)N)N4CCOCC4)O

InChIKey

LEXMMFPAPDGYGZ-UHFFFAOYSA-N

InChI

1S/C17H20N6O2S/c1-17(2,24)12-7-11-13(26-12)15(23-3-5-25-6-4-23)22-14(21-11)10-8-19-16(18)20-9-10/h7-9,24H,3-6H2,1-2H3,(H2,18,19,20)

关联靶标

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform