计算溶液所需的质量、体积或浓度。
WQQ-345 is a BCAT1 inhibitor with an IC 50 value of 10.8 mM. WQQ-345 can lead to a decrease in α-KG levels, an upregulation of H3K27me3 expression, a reduction in the expression of glycolytic enzymes ( PFKP and LDHA ), and impaired glycolytic activity in 67R cells. WQQ-345 shows tumor-suppressing activity in a 67R subcutaneous xenograft model.