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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
黄嘌呤氧化酶（XOD，EC 1.17.3.2）催化黄嘌呤氧化生成尿酸和超氧阴离子，是活性氧（ROS）的主要来源之一，同时也是核苷酸代谢的关键酶。XOD主要分布于哺乳动物的心、肺、肝脏等组织中，当肝功能受损时，XOD大量释放入血，对肝损伤的诊断具有重要的临床意义。本试剂盒的测定原理为：XOD催化黄嘌呤生成尿酸，尿酸在290 nm处具有特征吸收峰，通过测定290 nm处吸光度的变化速率，即可反映XOD的酶活性。
Xanthine oxidase (XOD, EC 1.17.3.2) catalyzes the oxidation of xanthine to uric acid and superoxide anion, and is one of the primary sources of reactive oxygen species (ROS), as well as a key enzyme in nucleotide metabolism. XOD is predominantly distributed in mammalian tissues such as the heart, lungs, and liver. When hepatic function is impaired, large amounts of XOD are released into the bloodstream, which holds significant clinical importance for the diagnosis of liver injury. The assay principle of this kit is as follows: XOD catalyzes the conversion of xanthine to uric acid, which exhibits a characteristic absorption peak at 290 nm. By measuring the rate of change in absorbance at 290 nm, the enzymatic activity of XOD can be determined.
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