计算溶液所需的质量、体积或浓度。
ZX-29
有货
Moligand™ 级 ,适用于对基线干扰要求严格的色谱和分析工作流程。
避光,-80℃储存。特低温运输 。请查阅批次 COA 获取详细规格。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
ZX-29 is a potent and selective ALK inhibitor with an IC 50 of 2.1 nM, 1.3 nM and 3.9 nM for ALK , ALK L1196M and ALK G1202R mutations, respectively. ZX-29 is inactive against EGFR . ZX-29 induces apoptosis by inducing endoplasmic reticulum (ER) stress and overcomes cell resistance caused by an ALK mutation. ZX-29 also induces protective autophagy and has antitumor effect.