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脒基硫脲

规格或纯度: 98%

CAS编号: 2114-02-5
分子式: C₂H₆N₄S
分子量: 118.16
EC号: 218-308-0
MDL号: MFCD00014472
PubChem编号: 2724563

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货号 (SKU)	包装规格	是否现货	价格	数量
A111256-5g	5g	现货
A111256-25g	25g	现货
A111256-100g	100g	现货
A111256-500g	500g	现货
A111256-2.5kg	2.5kg	现货

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含硫化合物非杂环砌块

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基本描述

别名	脒基硫脲\|硫氰酸胍\|2-亚氨基-4-硫化缩二脲
英文别名	Amidinothiourea\|GUANYLTHIOUREA\|2114-02-5\|2-Imino-4-thiobiuret\|diaminomethylidenethiourea\|Guthimin\|N-Amidinothiourea\|Thiodicyanodiamidine\|Thiourea, (aminoiminomethyl)-\|Guthimine\|Gutimine\|(diaminomethylidene)thiourea\|1-Amidinothiourea\|Urea, 1-amidino-2-thio
规格或纯度	98%
英文名称	Amidinothiourea
运输条件	常规运输
产品介绍	水中溶解度: 7 W/W % 水(20°C) Application 2-Imino-4-thiobiuret is used in the design and synthesis of guanylthiourea derivatives which are potential inhibitors of plasmodium falciparum dihydrofolate reductase enzyme. 2-Imino-4-thiobiuret is also used as a reagent in recyclization reactions of N-arylmaleimides with polynucleophilic compounds.

名称和标识符

PubChem SID	488192282
PubChem SID url	https://pubchem.ncbi.nlm.nih.gov/substance/488192282
EC号	218-308-0
IUPAC Name	diaminomethylidenethiourea
INCHI	InChI=1S/C2H6N4S/c3-1(4)6-2(5)7/h(H6,3,4,5,6,7)
InChi Key	OKGXJRGLYVRVNE-UHFFFAOYSA-N
Canonical SMILES	C(=NC(=S)N)(N)N
Isomeric SMILES	C(=NC(=S)N)(N)N
WGK Germany	3
RTECS	YR8250000
PubChem CID	2724563
分子量	118.16
Reaxy-Rn	1756620

数据库链接

PubChem SID	488192282

化学和物理性质

溶解性	Soluble in water (70g/L).
密度	1.73
熔点	160-164°C

安全和危险性（GHS）

象形图	Health Hazard Harmful
信号词	Warning
危险声明	H315: Causes skin irritation H319: Causes serious eye irritation H335: May cause respiratory irritation H302: Harmful if swallowed H361: Suspected of damaging fertility or the unborn child
预防措施声明	P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P270,P304+P340,P403+P233,P362+P364,P330,P203,P264+P265,P301+P317,P318,P337+P317,P332+P317,P319
WGK Germany	3
RTECS	YR8250000
Reaxy-Rn	1756620
个人防护装备	dust mask type N95 (US),Eyeshields,Gloves

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参考文献

1. N I Kochetygov,M I Remizova,L M Kozhevnikova. (1987-05-01) [Enhancement of the therapeutic efficacy of blood substitutes in burn shock].. Gematologiia i transfuziologiia, 32 ((5)): (35-38). [PMID:2440759]
2. V T Dolgikh. (1988-01-01) [Prevention of post-resuscitation impairment of energy metabolism in the myocardium using sodium gamma-hydroxybutyrate, ionol and gutimine].. Voprosy meditsinskoi khimii, 34 ((1)): (33-38). [PMID:3130722]
3. A A Waĭnson,O Iu Uriupov. (1986-05-01) [Radiation protection of mice with hypoxic gas mixtures after administration of anti-hypoxic agents].. Radiobiologiia, 26 ((3)): (329-333). [PMID:3461496]
4. C Vértesi. (1993-06-01) Immune response developing in tumorous organism as a result of immunotherapy. Chance of recovery?. Medical hypotheses, 40 ((6)): (335-341). [PMID:8377670]
5. G A Boiarinov,N N Andreeva,I V Mukhina. (1993-07-01) [Effect of using gutimine in the pre-ischemic period on myocardial phospholipids during reperfusion].. Voprosy meditsinskoi khimii, 39 ((4)): (34-38). [PMID:8379111]
6. A V Smirnov,B I Krivoruchko. (1997-05-01) [Hypoxia and its pharmacological correction: a key problem of anesthesiology and intensive care].. Anesteziologiia i reanimatologiia, ((3)): (97-98). [PMID:9290001]
7. A V Smirnov,B I Krivoruchko. (1998-06-05) [Antihypoxants in emergency medicine].. Anesteziologiia i reanimatologiia, ((2)(2)): (50-55). [PMID:9612972]
8. I V Zarubina,M V Lukk,P D Shabanov. (2012-08-07) Antihypoxic and antioxidant effects of exogenous succinic acid and aminothiol succinate-containing antihypoxants.. Bulletin of experimental biology and medicine, 153 ((3)): (336-339). [PMID:22866305]
9. V T Dolgikh,V V Rusakov,O V Korpacheva,A N Sudakova. (1992-06-01) Pathogenesis and pharmacorrection of early postresuscitation cardiac arrhythmia.. Resuscitation, 23 ((3)): (179-191). [PMID:1321477]
10. S S Sergeeva,I N Ianvareva,O Iu Uriupov,A B Tomchin. (1991-05-01) [The action of amtizol and gutimin on the respiratory metabolism of the neuron].. Farmakologiia i toksikologiia, 54 ((3)): (22-24). [PMID:1915813]
11. I N Petrin,V T Dolgikh,I P Krolevets. (1993-11-01) [The use of sodium gamma-oxybutyrate and gutimine for decreasing metabolic disorders in the heart, caused by exotoxic shock in acetic acid poisoning].. Voprosy meditsinskoi khimii, 39 ((6)): (36-39). [PMID:8303871]
12. Ahmed Mehdi,Legesse Adane,Dhilon S Patel,Prasad V Bharatam. (2009-11-06) Electronic structure and reactivity of guanylthiourea: a quantum chemical study.. Journal of computational chemistry, 31 ((6)): (1259-1267). [PMID:19890877]
13. Royce A Wilkinson,Seth H Pincus,Joyce B Shepard,Sarah K Walton,Edward P Bergin,Mohamed Labib,Martin Teintze. (2010-10-13) Novel compounds containing multiple guanide groups that bind the HIV coreceptor CXCR4.. Antimicrobial agents and chemotherapy, 55 ((1)): (255-263). [PMID:20937786]

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