为了获得访问"阿拉丁铁蛋"实时聊天框的流畅支持体验,建议您使用Chrome浏览器或选择360浏览器极速模式(如何切换极速模式?),感谢您选择我们!

柠康酐

规格或纯度: 98%
有货

库存信息

关闭

库存信息

关闭

库存信息

关闭

库存信息

关闭

库存信息

关闭

库存信息

关闭
货号 (SKU) 包装规格 是否现货 价格 数量
C106959-5g
5g 现货 Stock Image
C106959-10g
10g 现货 Stock Image
C106959-25g
25g 现货 Stock Image
C106959-100g
100g 现货 Stock Image
C106959-500g
500g 现货 Stock Image
C106959-2.5kg
2.5kg 现货 Stock Image

基本描述

别名 柠康酸酐|3-甲基-2,5-呋喃二酮|单甲基马来酸酐|甲基马来酸酐|2-甲基马来酸酐
英文别名 Citraconic anhydride|616-02-4|3-methylfuran-2,5-dione|2,5-Furandione, 3-methyl-|2-Methylmaleic anhydride|METHYLMALEIC ANHYDRIDE|3-Methylmaleic anhydride|Citraconic acid anhydride|Monomethylmaleic anhydride|Maleic anhydride, methyl-|3-methyl-2,5-dihydrofur
规格或纯度 98%
英文名称 Citraconic anhydride
储存温度 充氩
运输条件 常规运输
产品介绍

水中分解。 用于合成马来酰亚胺、二环吡咯烷和三元共聚物的常用试剂,也用于保护N-末端氨基酸。

Versatile reagent used for the synthesis of maleimides, bicyclic pyrrolidines, and co- and terpolymers, as well as for the protection of N-terminal amino acids.

名称和标识符

PubChem SID 488181510
PubChem SID url https://pubchem.ncbi.nlm.nih.gov/substance/488181510
EC号 210-459-0
IUPAC Name 3-methylfuran-2,5-dione
INCHI InChI=1S/C5H4O3/c1-3-2-4(6)8-5(3)7/h2H,1H3
InChi Key AYKYXWQEBUNJCN-UHFFFAOYSA-N
Canonical SMILES CC1=CC(=O)OC1=O
Isomeric SMILES CC1=CC(=O)OC1=O
WGK Germany 3
RTECS GE6825000
PubChem CID 12012
UN Number 2810
分子量 112.08
Beilstein号 1835
Reaxy-Rn 1835

化学和物理性质

溶解性 Miscible with water, alcohol, acetone and eth
密度 1.247
敏感性 对湿度敏感
凝固点 7 °C
折光率 1.47-1.472
闪点(℉) 101℃
闪点(℃) 101℃
沸点 213°C
熔点 6-7°C

安全和危险性(GHS)

象形图
ghs06

Toxic

ghs08

Health Hazard

ghs05

Corrosive

ghs07

Harmful

信号词 Danger
危险声明 H335: May cause respiratory irritation
H311: Toxic in contact with skin
H314: Causes severe skin burns and eye damage
H318: Causes serious eye damage
H317: May cause an allergic skin reaction
H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled
预防措施声明 P261,P280,P302+P352,P321,P405,P501,P264,P260,P284,P271,P301+P330+P331,P304+P340,P363,P403+P233,P272,P333+P313,P362+P364,P361+P364,P264+P265,P305+P354+P338,P317,P302+P361+P354,P316,P319,P342+P316
WGK Germany 3
RTECS GE6825000
Reaxy-Rn 1835
个人防护装备 Eyeshields,Faceshields,full-face respirator (US),Gloves,multi-purpose combination respirator cartridge (US),type ABEK (EN14387) respirator filter

质检证书(COA)

质检报告(COA)

输入批号以搜索COA:

相关文档

质检报告COA

请输入批号:


产品问答

产品问答

登录提交问题 Hover me 请先登录再提交问题
您提交该产品问题后,我们会在1-2个工作日内给您答复,您可以登录"我的账号",然后点击"我的产品问答"查看答案

参考文献

1. P P Batra.  (1991-01-01)  Conformational stability of citraconylated ovalbumin..  The International journal of biochemistry,  23  ((12)):  (1375-1384).  [PMID:1761147]
2. P P Batra.  (1991-11-01)  Regeneration of native ovalbumin conformation disrupted by citraconylation..  Biochimie,  73  ((11)):  (1397-1402).  [PMID:1799633]
3. A Fischer,A Schwarz,C Wandrey,A S Bommarius,G Knaup,K Drauz.  (1991-01-01)  Preparative-scale enzyme-catalyzed peptide synthesis using solubilizing N-terminal protecting groups..  Biomedica biochimica acta,  50  ((10-11)):  (S169-S174).  [PMID:1840289]
4. A F Habeeb.  (1987-08-01)  Schistosoma mansoni: chemical stabilization of cercariae by aldehydes..  Experimental parasitology,  64  ((1)):  (111-119).  [PMID:3111876]
5. W Rychlik,M A Russ,R E Rhoads.  (1987-08-05)  Phosphorylation site of eukaryotic initiation factor 4E..  The Journal of biological chemistry,  262  ((22)):  (10434-10437).  [PMID:3112145]
6. A R Gould,R S Norton.  (1995-02-01)  Chemical modification of cationic groups in the polypeptide cardiac stimulant anthopleurin-A..  Toxicon : official journal of the International Society on Toxinology,  33  ((2)):  (187-199).  [PMID:7597722]
7. C Illy,N M Thielens,G J Arlaud.  (1993-12-01)  Chemical characterization and location of ionic interactions involved in the assembly of the C1 complex of human complement..  Journal of protein chemistry,  12  ((6)):  (771-781).  [PMID:8136028]
8. Vojtech Kadlík,Martin Strohalm,Milan Kodícek.  (2003-05-28)  Citraconylation--a simple method for high protein sequence coverage in MALDI-TOF mass spectrometry..  Biochemical and biophysical research communications,  305  ((4)):  (1091-1093).  [PMID:12767943]
9. Saman Hosseinkhani,Bijan Ranjbar,Hossein Naderi-Manesh,Mohsen Nemat-Gorgani.  (2004-03-12)  Chemical modification of glucose oxidase: possible formation of molten globule-like intermediate structure..  FEBS letters,  561  ((1-3)):  (213-216).  [PMID:15013780]
10. Regina Knitter,Marcel A Liauw.  (2004-07-23)  Ceramic microreactors for heterogeneously catalysed gas-phase reactions..  Lab on a chip,  ((4)):  (378-383).  [PMID:15269808]
11. W Dai,S Sato,M Ishizaki,K Wakamatsu,S Namimatsu,Y Sugisaki,M Ghazizadeh.  (2005-05-24)  A new antigen retrieval method using citraconic anhydride for immunoelectron microscopy: localization of surfactant pro-protein C (proSP-C) in the type II alveolar epithelial cells..  Journal of submicroscopic cytology and pathology,  36  ((3-4)):  (219-224).  [PMID:15906596]
12. Jian-Zhong Liu,Teng-Li Wang,Ming-Tao Huang,Hai-Yan Song,Li-Ping Weng,Liang-Nian Ji.  (2006-02-03)  Increased thermal and organic solvent tolerance of modified horseradish peroxidase..  Protein engineering, design & selection : PEDS,  19  ((4)):  (169-173).  [PMID:16452119]
13. Shahla Mossavarali,Saman Hosseinkhani,Bijan Ranjbar,Mehran Miroliaei.  (2006-05-10)  Stepwise modification of lysine residues of glucose oxidase with citraconic anhydride..  International journal of biological macromolecules,  39  ((4-5)):  (192-196).  [PMID:16682074]
14. Yan Lee,Shigeto Fukushima,Younsoo Bae,Shigehiro Hiki,Takehiko Ishii,Kazunori Kataoka.  (2007-04-06)  A protein nanocarrier from charge-conversion polymer in response to endosomal pH..  Journal of the American Chemical Society,  129  ((17)):  (5362-5363).  [PMID:17408272]
15. Jian-Zhong Liu,Min Wang.  (2007-05-22)  Improvement of activity and stability of chloroperoxidase by chemical modification..  BMC biotechnology,  ():  (23-23).  [PMID:17511866]
16. Young-Jin Son,Chang-Kyu Kim,Young Bong Kim,Dae-Hyuk Kweon,Yong-Cheol Park,Jin-Ho Seo.  (2009-07-03)  Effects of citraconylation on enzymatic modification of human proinsulin using trypsin and carboxypeptidase B..  Biotechnology progress,  25  ((4)):  (1064-1070).  [PMID:19572292]
17. Em-orn Phanomsri,Nisana Namwat,Roongpet Tangrassameeprasert,Charn Charnteeraprawat,Anucha Paupiroj.  (2011-02-09)  Comparative study for the detection of C4d in paraffin-embedded renal allograft biopsies by immunohistochemical techniques..  Journal of the Medical Association of Thailand = Chotmaihet thangphaet,  93 Suppl 3  ():  (S61-S68).  [PMID:21302408]
18. Jun Cao,Ting Su,Longgui Zhang,Rong Liu,Gang Wang,Bin He,Zhongwei Gu.  (2014-05-20)  Polymeric micelles with citraconic amide as pH-sensitive bond in backbone for anticancer drug delivery..  International journal of pharmaceutics,  471  ((1-2)):  (28-36).  [PMID:24836667]
19. Thomas W Powers,Benjamin A Neely,Yuan Shao,Huiyuan Tang,Dean A Troyer,Anand S Mehta,Brian B Haab,Richard R Drake.  (2014-09-04)  MALDI imaging mass spectrometry profiling of N-glycans in formalin-fixed paraffin embedded clinical tissue blocks and tissue microarrays..  PloS one,  ((9)):  (e106255-e106255).  [PMID:25184632]
20. Lu Han,Cui Tang,Chunhua Yin.  (2015-01-27)  Enhanced antitumor efficacies of multifunctional nanocomplexes through knocking down the barriers for siRNA delivery..  Biomaterials,  44  ():  (111-121).  [PMID:25617131]
21. Daniel Garcia-Ovejero,Angel Arevalo-Martin,Beatriz Paniagua-Torija,José Florensa-Vila,Isidro Ferrer,Lukas Grassner,Eduardo Molina-Holgado.  (2015-04-18)  The ependymal region of the adult human spinal cord differs from other species and shows ependymoma-like features..  Brain : a journal of neurology,  138  ((Pt 6)):  (1583-1597).  [PMID:25882650]
22. Xing Pei Hao,Carissa M Lucero,Baris Turkbey,Marcelino L Bernardo,David R Morcock,Claire Deleage,Charles M Trubey,Jeremy Smedley,Nichole R Klatt,Luis D Giavedoni,Jan Kristoff,Amy Xu,Gregory Q Del Prete,Brandon F Keele,Srinivas S Rao,W Gregory Alvord,Peter L Choyke,Jeffrey D Lifson,Jason M Brenchley,Cristian Apetrei,Ivona Pandrea,Jacob D Estes.  (2015-08-19)  Experimental colitis in SIV-uninfected rhesus macaques recapitulates important features of pathogenic SIV infection..  Nature communications,  ():  (8020-8020).  [PMID:26282376]
23. Rong-Qiao Cai,Dao-Zhou Liu,Han Cui,Ying Cheng,Miao Liu,Bang-Le Zhang,Qi-Bing Mei,Si-Yuan Zhou.  (2017-05-18)  Charge reversible calcium phosphate lipid hybrid nanoparticle for siRNA delivery..  Oncotarget,  ((26)):  (42772-42788).  [PMID:28514759]
24. Raphael Haase,Sebastian Alexander Potthoff,Catherine Meyer-Schwesinger,Clara Frosch,Thorsten Wiech,Ulf Panzer,Eva Königshausen,Johannes Stegbauer,Lorenz Sellin,Lars Christian Rump,Ivo Quack,Magdalena Woznowski.  (2017-06-13)  A novel in vivo method to quantify slit diaphragm protein abundance in murine proteinuric kidney disease..  PloS one,  12  ((6)):  (e0179217-e0179217).  [PMID:28604827]
25. You Li,Man Li,Tao Gong,Zhirong Zhang,Xun Sun.  (2017-08-02)  Antigen-loaded polymeric hybrid micelles elicit strong mucosal and systemic immune responses after intranasal administration..  Journal of controlled release : official journal of the Controlled Release Society,  262  ():  (151-158).  [PMID:28756271]
26. Nicole Blanchette-Farra,Daniel Kita,Anna Konstorum,Lia Tesfay,David Lemler,Poornima Hegde,Kevin P Claffey,Frank M Torti,Suzy V Torti.  (2018-04-27)  Contribution of three-dimensional architecture and tumor-associated fibroblasts to hepcidin regulation in breast cancer..  Oncogene,  37  ((29)):  (4013-4032).  [PMID:29695834]
27. Yunden Jinsmaa,Yehonatan Sharabi,Patti Sullivan,Risa Isonaka,David S Goldstein.  (2018-04-28)  3,4-Dihydroxyphenylacetaldehyde-Induced Protein Modifications and Their Mitigation by N-Acetylcysteine..  The Journal of pharmacology and experimental therapeutics,  366  ((1)):  (113-124).  [PMID:29700232]
28. Alexandra M Ortiz,Jacob K Flynn,Sarah R DiNapoli,Ivan Vujkovic-Cvijin,Carly E Starke,Stephen H Lai,MacKenzie E Long,Ornella Sortino,Carol L Vinton,Joseph C Mudd,Leslie Johnston,Kathleen Busman-Sahay,Yasmine Belkaid,Jacob D Estes,Jason M Brenchley.  (2018-08-01)  Experimental microbial dysbiosis does not promote disease progression in SIV-infected macaques..  Nature medicine,  24  ((9)):  (1313-1316).  [PMID:30061696]
29. Joseph C Mudd,Kathleen Busman-Sahay,Sarah R DiNapoli,Stephen Lai,Virginia Sheik,Andrea Lisco,Claire Deleage,Brian Richardson,David J Palesch,Mirko Paiardini,Mark Cameron,Irini Sereti,R Keith Reeves,Jacob D Estes,Jason M Brenchley.  (2018-09-29)  Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells..  Nature communications,  ((1)):  (3967-3967).  [PMID:30262807]
30. Zuowei Ji,Alex Sheardy,Zheng Zeng,Wendi Zhang,Harish Chevva,Kokougan Allado,Ziyu Yin,Jianjun Wei.  (2019-01-06)  Tuning the Functional Groups on Carbon Nanodots and Antioxidant Studies..  Molecules (Basel, Switzerland),  24  ((1)):  ().  [PMID:30609752]
31. Carlos González-Fernández,Pau Gonzalez,Pol Andres-Benito,Isidro Ferrer,Francisco Javier Rodríguez.  (2019-03-30)  Wnt Signaling Alterations in the Human Spinal Cord of Amyotrophic Lateral Sclerosis Cases: Spotlight on Fz2 and Wnt5a..  Molecular neurobiology,  56  ((10)):  (6777-6791).  [PMID:30924074]
32. Tomohiro Ito,Kanae Bekki,Yuji Fujitani,Seishiro Hirano.  (2019-06-07)  The toxicological analysis of secondary organic aerosol in human lung epithelial cells and macrophages..  Environmental science and pollution research international,  26  ((22)):  (22747-22755).  [PMID:31172435]
33. Robert Ludmerczki,Stefania Mura,Carlo Maria Carbonaro,Istvan M Mandity,Massimo Carraro,Nina Senes,Sebastiano Garroni,Gaetano Granozzi,Laura Calvillo,Sergio Marras,Luca Malfatti,Plinio Innocenzi.  (2019-06-30)  Carbon Dots from Citric Acid and its Intermediates Formed by Thermal Decomposition..  Chemistry (Weinheim an der Bergstrasse, Germany),  25  ((51)):  (11963-11974).  [PMID:31254368]
34. Tao Zheng,Wentao Wang,Fan Wu,Ming Zhang,Jian Shen,Yi Sun.  (2019-08-15)  Zwitterionic Polymer-Gated Au@TiO2 Core-Shell Nanoparticles for Imaging-Guided Combined Cancer Therapy..  Theranostics,  ((17)):  (5035-5048).  [PMID:31410200]
35. Anh H Cao-Pham,Kum C Hiong,Mel V Boo,Celine Y L Choo,Wai P Wong,Shit F Chew,Yuen K Ip.  (2019-10-06)  Calcium absorption in the fluted giant clam, Tridacna squamosa, may involve a homolog of voltage-gated calcium channel subunit α1 (CACNA1) that has an apical localization and displays light-enhanced protein expression in the ctenidium..  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology,  189  ((6)):  (693-706).  [PMID:31586259]
36. Ying Li,Yunqiu Miao,Mingshu Chen,Xi Chen,Feifei Li,Xinxin Zhang,Yong Gan.  (2020-03-25)  Stepwise targeting and responsive lipid-coated nanoparticles for enhanced tumor cell sensitivity and hepatocellular carcinoma therapy..  Theranostics,  10  ((8)):  (3722-3736).  [PMID:32206118]
37. Yingying Hou,Ying Wang,Yao Tang,Zixuan Zhou,Lu Tan,Tao Gong,Ling Zhang,Xun Sun.  (2020-06-26)  Co-delivery of antigen and dual adjuvants by aluminum hydroxide nanoparticles for enhanced immune responses..  Journal of controlled release : official journal of the Controlled Release Society,  326  ():  (120-130).  [PMID:32585230]
38. D A Johnson,R Cushman.  (1988-02-25)  Purification and characterization of four monofluorescein cobra alpha-toxin derivatives..  The Journal of biological chemistry,  263  ((6)):  (2802-2807).  [PMID:3125169]
39. L Becker,R S McLeod,S M Marcovina,Z Yao,M L Koschinsky.  (2001-07-27)  Identification of a critical lysine residue in apolipoprotein B-100 that mediates noncovalent interaction with apolipoprotein(a)..  The Journal of biological chemistry,  276  ((39)):  (36155-36162).  [PMID:11473115]
40. Dina Morshedi,Azadeh Ebrahim-Habibi,Ali Akbar Moosavi-Movahedi,Mohsen Nemat-Gorgani.  (2009-12-01)  Chemical modification of lysine residues in lysozyme may dramatically influence its amyloid fibrillation..  Biochimica et biophysica acta,  1804  ((4)):  (714-722).  [PMID:19945549]
41. Anthony S-Y Leong,Zenobia Haffajee.  (2009-12-23)  Citraconic anhydride: a new antigen retrieval solution..  Pathology,  42  ((1)):  (77-81).  [PMID:20025485]
42. Kun Zhang,Wenming Yang,Dawei Wang,Congcong Liu,Linshuang Qi,Yongjian Wang.  (2011-12-27)  Tumor-targeted drug carriers and their enhanced intracellular delivery by pH-sensitivity..  Journal of controlled release : official journal of the Controlled Release Society,  152 Suppl 1  ():  (e95-e97).  [PMID:22195954]
43. K Moriguchi,Y Mitamura,J Iwami,Y Hasegawa,N Higuchi,Y Murakami,H Maeda,F Yoshimura,H Nakamura,N Ohno.  (2012-09-19)  Energy filtering transmission electron microscopy immunocytochemistry and antigen retrieval of surface layer proteins from Tannerella forsythensis using microwave or autoclave heating with citraconic anhydride..  Biotechnic & histochemistry : official publication of the Biological Stain Commission,  87  ((8)):  (485-493).  [PMID:22984898]
44. M W Laschke,S Kleer,C Scheuer,D Eglin,M Alini,M D Menger.  (2015-03-22)  Pre-cultivation of adipose tissue-derived microvascular fragments in porous scaffolds does not improve their in vivo vascularisation potential..  European cells & materials,  29  ():  (190-200).  [PMID:25794528]
45. Lu Han,Cui Tang,Chunhua Yin.  (2015-05-20)  Dual-targeting and pH/redox-responsive multi-layered nanocomplexes for smart co-delivery of doxorubicin and siRNA..  Biomaterials,  60  ():  (42-52).  [PMID:25982552]
46. Menglu Xu,Yulin Chen,Parikshit Banerjee,Li Zong,Lei Jiang.  (2017-03-01)  Dendritic Cells Targeting and pH-Responsive Multi-layered Nanocomplexes for Smart Delivery of DNA Vaccines..  AAPS PharmSciTech,  18  ((7)):  (2618-2625).  [PMID:28243887]
47. Syed Mukhtar Ahmed,Ian G Macara.  (2017-03-31)  The Par3 polarity protein is an exocyst receptor essential for mammary cell survival..  Nature communications,  ():  (14867-14867).  [PMID:28358000]
48. Santhosh Kalash Rajendrakumar,Kondareddy Cherukula,Hyeong Ju Park,Saji Uthaman,Yong Yeon Jeong,Byeong-Il Lee,In-Kyu Park.  (2018-03-03)  Dual-stimuli-responsive albumin-polyplex nanoassembly for spatially controlled gene release in metastatic breast cancer..  Journal of controlled release : official journal of the Controlled Release Society,  276  ():  (72-83).  [PMID:29499218]
49. Ingrit Hamann,Daniel Krys,Darryl Glubrecht,Vincent Bouvet,Alison Marshall,Larissa Vos,John R Mackey,Melinda Wuest,Frank Wuest.  (2018-06-20)  Expression and function of hexose transporters GLUT1, GLUT2, and GLUT5 in breast cancer-effects of hypoxia..  FASEB journal : official publication of the Federation of American Societies for Experimental Biology,  32  ((9)):  (5104-5118).  [PMID:29913554]
50. Hong Yang,Xue Shen,Jie Yan,Xiaoxue Xie,Zhongyuan Chen,Tingting Li,Shun Li,Xiang Qin,Chunhui Wu,Yiyao Liu.  (2018-07-25)  Charge-reversal-functionalized PLGA nanobubbles as theranostic agents for ultrasonic-imaging-guided combination therapy..  Biomaterials science,  ((9)):  (2426-2439).  [PMID:30040100]
51. Brandon F Maziuk,Daniel J Apicco,Anna Lourdes Cruz,Lulu Jiang,Peter E A Ash,Edroaldo Lummertz da Rocha,Cheng Zhang,Wai Haung Yu,John Leszyk,Jose F Abisambra,Hu Li,Benjamin Wolozin.  (2018-08-03)  RNA binding proteins co-localize with small tau inclusions in tauopathy..  Acta neuropathologica communications,  ((1)):  (71-71).  [PMID:30068389]
52. Vikalp Vishwakarma,Jacob New,Dhruv Kumar,Vusala Snyder,Levi Arnold,Emily Nissen,Qingting Hu,Nikki Cheng,David Miller,Ahia Rael Thomas,Yelizaveta Shnayder,Kiran Kakarala,Terance Ted Tsue,Douglas A Girod,Sufi Mary Thomas.  (2018-08-17)  Potent Antitumor Effects of a Combination of Three Nutraceutical Compounds..  Scientific reports,  ((1)):  (12163-12163).  [PMID:30111862]
53. Andrey Kazakov,Rabea A Hall,Christian Werner,Timo Meier,André Trouvain,Svetlana Rodionycheva,Alexander Nickel,Frank Lammert,Christoph Maack,Michael Böhm,Ulrich Laufs.  (2018-09-08)  Raf kinase inhibitor protein mediates myocardial fibrosis under conditions of enhanced myocardial oxidative stress..  Basic research in cardiology,  113  ((6)):  (42-42).  [PMID:30191336]
54. Yudong Song,Cui Tang,Chunhua Yin.  (2018-09-22)  Combination antitumor immunotherapy with VEGF and PIGF siRNA via systemic delivery of multi-functionalized nanoparticles to tumor-associated macrophages and breast cancer cells..  Biomaterials,  185  ():  (117-132).  [PMID:30241030]
55. Jenni E Anttila,Suvi Pöyhönen,Mikko Airavaara.  (2019-05-01)  Secondary Pathology of the Thalamus after Focal Cortical Stroke in Rats is not Associated with Thermal or Mechanical Hypersensitivity and is Not Alleviated by Intra-Thalamic Post-Stroke Delivery of Recombinant CDNF or MANF..  Cell transplantation,  28  ((4)):  (425-438).  [PMID:31037983]