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2'-(3,4-二甲氧基苯基)-5-(4-甲基-1-哌嗪基)-2,5'-双[1H-苯并咪唑](DMA)

规格或纯度: 97%
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货号 (SKU) 包装规格 是否现货 价格 数量
D125044-5mg
 5mg 现货 Stock Image
D125044-25mg
 25mg 现货 Stock Image
D125044-50mg
 50mg 现货 Stock Image
D125044-100mg
 100mg 现货 Stock Image
D125044-250mg
 250mg 现货 Stock Image
大包装询价 添加到收藏夹 比较  SDS中文版  DATASHEET
main product photo

基本描述

英文别名 188860-26-6|2,5'-Bi-1H-benzimidazole, 2'-(3,4-dimethoxyphenyl)-5-(4-methyl-1-piperazinyl)-|2-(3,4-dimethoxyphenyl)-6-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-benzimidazole|DMA (hydrochloride)|CHEMBL125284|SCHEMBL1552158|DTXSID80436348|NSC82290
规格或纯度 97%
英文名称 DMA
生化机理

Description:
IC50 Value: N/A
Hoechst stains are part of a family of blue fluorescent dyes used to stain DNA. These Bis-benzimides were originally developed by Hoechst AG, which numbered all their compounds so that the dye Hoechst 33342 is the 33342nd compound made by the company. There are three related Hoechst stains: Hoechst 33258, Hoechst 33342, and Hoechst 34580. The dyes Hoechst 33258 and Hoechst 33342 are the ones most commonly used and they have similarexcitation/emission spectra. Both dyes are excited by ultraviolet light at around 350 nm, and both emit blue/cyan fluorescent light around anemission maximum at 461 nm. Unbound dye has its maximum fluorescence emission in the 510-540 nm range. Hoechst dyes are soluble in water and in organic solvents such as dimethyl formamide or dimethyl sulfoxide. Concentrations can be achieved of up to 10 mg/mL. Aqueous solutions are stable at 2-6 °C for at least six months when protected from light. For long-term storage the solutions are instead frozen at ≤-20 °C.
The dyes bind to the minor groove of double-stranded DNA with a preference for sequences rich in adenine andthymine. Althoμgh the dyes can bind to all nucleic acids, AT-rich double-stranded DNA strands enhance fluorescence considerably.
Hoechst dyes are cell-permeable and can bind to DNA in live or fixed cells. Therefore, these stains are often called supravital, which means that cells survive a treatment with these compounds. Cells that express specific ATP-binding cassette transporter proteins can also actively transport these stains out of their cytoplasm.
in vitro: N/A
in vivo: N/A
Clinical trial: N/A
 

储存温度 -20°C储存
运输条件 超低温冰袋运输
产品介绍

DMA 是一种荧光化合物 (λex=340 nm, λem=478 nm)。

DMA is a fluorescent compound (λex=340 nm, λem=478 nm).

名称和标识符

IUPAC Name 2-(3,4-dimethoxyphenyl)-6-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-benzimidazole
INCHI InChI=1S/C27H28N6O2/c1-32-10-12-33(13-11-32)19-6-8-21-23(16-19)31-26(29-21)17-4-7-20-22(14-17)30-27(28-20)18-5-9-24(34-2)25(15-18)35-3/h4-9,14-16H,10-13H2,1-3H3,(H,28,30)(H,29,31)
InChi Key BMRRDFCQNOZNNR-UHFFFAOYSA-N
Canonical SMILES CN1CCN(CC1)C2=CC3=C(C=C2)N=C(N3)C4=CC5=C(C=C4)N=C(N5)C6=CC(=C(C=C6)OC)OC
Isomeric SMILES CN1CCN(CC1)C2=CC3=C(C=C2)N=C(N3)C4=CC5=C(C=C4)N=C(N5)C6=CC(=C(C=C6)OC)OC
PubChem CID 10174012
分子量 468.55

化学和物理性质

溶解性 25°C: DMSO or water Protect from light

质检证书(COA)

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