| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| D649967-5mg |
5mg |
期货  |
| |
| D649967-10mg |
10mg |
期货 |
|
| 规格或纯度 | ≥96% |
|---|---|
| 英文名称 | diABZI-C2-NH2 |
| 生化机理 | diABZI-C2-NH2 是一种含有伯胺官能团的活性类似物，是一种 STING 激动剂。 |
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 产品介绍 |
diABZI-C2-NH2, an active analogue containing a primary amine functionality, is a STING agonist. In Vitro The author developed a linking strategy to synergize the effect of two symmetry-related amidobenzimidazole (ABZI)-based compounds to create linked ABZIs (diABZIs) with enhanced binding to STING and cellular function. Intravenous administration of a diABZI STING agonist to immunocompetent mice with established syngeneic colon tumours elicited strong anti-tumour activity, with complete and lasting regression of tumors. diABZI-C2-NH2 is covalently immobilized on sepharose beads and is used to affinity-capture potential target proteins from a THP1 cell lysate. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid |
| Canonical SMILES | O=C(C1=CC=C2C(N=C(NC(C3=CC(C)=NN3CC)=O)N2CCCCN4C5=CC=C(C(N)=O)C=C5N=C4NC(C6=CC(C)=NN6CC)=O)=C1)NCCN |
|---|---|
| 分子量 | 721.81 |
| 溶解性 | DMSO : 100 mg/mL (138.54 mM; Need ultrasonic) |
|---|
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