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5-硝基-2-糠醛

规格或纯度: >98.0%(GC)
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货号 (SKU) 包装规格 是否现货 价格 数量
N159009-5g
5g 现货 Stock Image
N159009-10g
10g 现货 Stock Image
N159009-25g
25g 现货 Stock Image
N159009-100g
100g 现货 Stock Image
N159009-500g
500g 现货 Stock Image

基本描述

别名 5-硝基糠醛|5-硝基-2-呋喃甲醛|5-硝基呋喃-2-甲醛
英文别名 5-NITRO-2-FURALDEHYDE|5-Nitrofurfural|698-63-5|5-nitrofuran-2-carbaldehyde|5-Nitrofurfuraldehyde|Nitrofurfural|2-Furancarboxaldehyde, 5-nitro-|5-Nitro-2-furancarboxaldehyde|5-Nitro-2-furfural|2-Furaldehyde, 5-nitro-|Furfural, 5-nitro-|5-Nitrofuraldehyde|N
规格或纯度 >98.0%(GC)
英文名称 5-Nitro-2-furaldehyde
应用 5-Nitro-2-furaldehyde was used in the synthesis of a series of 4-(5-nitrofuran-2-yl)prop-2-en-1-one derivatives. It was also used in the synthesis of modified mesoporous silica.
储存温度 避光,充氩
运输条件 常规运输
产品介绍

易燃固体,远离热源、火花、明火和热表面。使用防爆的电器、通风设施和照明设备。5-Nitro-2-furaldehyde was used in the synthesis of a series of 4-(5-nitrofuran-2-yl)prop-2-en-1-one derivatives. It was also used in the synthesis of modified mesoporous silica.

Screening of Potential anti-Trypanosoma cruzi Candidates: In Vitro and In Vivo Studies.
5-Nitro-2-furaldehyde was used in the synthesis of a series of 4-(5-nitrofuran-2-yl)prop-2-en-1-one derivatives. It was also used in the synthesis of modified mesoporous silica.

名称和标识符

IUPAC Name 5-nitrofuran-2-carbaldehyde
INCHI InChI=1S/C5H3NO4/c7-3-4-1-2-5(10-4)6(8)9/h1-3H
InChi Key SXINBFXPADXIEY-UHFFFAOYSA-N
Canonical SMILES C1=C(OC(=C1)[N+](=O)[O-])C=O
Isomeric SMILES C1=C(OC(=C1)[N+](=O)[O-])C=O
WGK Germany 3
RTECS LT7200000
PubChem CID 12774
分子量 141.08
Beilstein号 120539
Reaxy-Rn 120539

化学和物理性质

溶解性 可溶于乙醚,微溶于水
密度 1.349
敏感性 对空气、光敏感
折光率 1.59
闪点(℉) 91.4 °F
闪点(℃) 33 °C
沸点 121 °C
熔点 37-39°C

安全和危险性(GHS)

象形图
ghs08

Health Hazard

ghs02

Flammable

信号词 Warning
危险声明 H341: Suspected of causing genetic defects
H228: Flammable solid
预防措施声明 P280,P370+P378,P210,P405,P501,P240,P281,P241,P203,P318
WGK Germany 3
RTECS LT7200000
Reaxy-Rn 120539
个人防护装备 Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

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参考文献

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5. Jun Li,Jing Liu,Hui-Cai Zhang,Hui Li,Jian-Ping Wang.  (2010-09-28)  Broad specificity indirect competitive immunoassay for determination of nitrofurans in animal feeds..  Analytica chimica acta,  678  ((1)):  (1-6).  [PMID:20869497]
6. M Arivazhagan,S Jeyavijayan,J Geethapriya.  (2013-01-01)  Conformational stability, vibrational spectra, molecular structure, NBO and HOMO-LUMO analysis of 5-nitro-2-furaldehyde oxime based on DFT calculations..  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy,  104  ():  (14-25).  [PMID:23274252]
7. Shuai Zhang,Yuanming Guo,Zhongyong Yan,Xiumei Sun,Xiaojun Zhang.  (2015-10-03)  A selective biomarker for confirming nitrofurazone residues in crab and shrimp using ultra-performance liquid chromatography-tandem mass spectrometry..  Analytical and bioanalytical chemistry,  407  ((30)):  (8971-8977).  [PMID:26427505]
8. Jarosław Lewkowski,Marta Morawska,Rafał Karpowicz,Piotr Rychter,Diana Rogacz,Kamila Lewicka.  (2017-09-17)  Novel (5-nitrofurfuryl)-substituted esters of phosphonoglycine - Their synthesis and phyto- and ecotoxicological properties..  Chemosphere,  188  ():  (618-632).  [PMID:28917214]
9. Hui Li,Zhengyu Zhang,Xiaojing Yang,Xu Mao,Ying Wang,Jian Wang,Ying Peng,Jiang Zheng.  (2019-02-20)  Electron Deficiency of Nitro Group Determines Hepatic Cytotoxicity of Nitrofurantoin..  Chemical research in toxicology,  32  ((4)):  (681-690).  [PMID:30779552]
10. C Gallardo-Garrido,Y Cho,J Cortés-Rios,D Vasquez,C D Pessoa-Mahana,R Araya-Maturana,H Pessoa-Mahana,M Faundez.  (2020-06-13)  Nitrofuran drugs beyond redox cycling: Evidence of Nitroreduction-independent cytotoxicity mechanism..  Toxicology and applied pharmacology,  401  ():  (115104-115104).  [PMID:32531296]
11. R W Busker,G M Beijersbergen van Henegouwen,G J Vaassen,R F Menke.  (1989-11-01)  Irreversible photobinding of nitrofurantoin and of nitrofurfural to plasma proteins in vitro..  Journal of photochemistry and photobiology. B, Biology,  ((2)):  (207-218).  [PMID:2512382]
12. R W Busker,G M Beijersbergen van Henegouwen.  (1987-07-01)  Cytotoxicity and induction of repairable DNA damage by photoactivated 5-nitrofurfural..  Toxicology,  45  ((1)):  (103-112).  [PMID:3299875]
13. H Cerecetto,R Di Maio,M González,M Risso,G Sagrera,G Seoane,A Denicola,G Peluffo,C Quijano,A O Stoppani,M Paulino,C Olea-Azar,M A Basombrío.  (2000-04-29)  Synthesis and antitrypanosomal evaluation of E-isomers of 5-nitro-2-furaldehyde and 5-nitrothiophene-2-carboxaldehyde semicarbazone derivatives. structure-activity relationships..  European journal of medicinal chemistry,  35  ((3)):  (343-350).  [PMID:10785560]
14. Seyed Reza Yousefi,Seyed Javad Ahmadi,Farzaneh Shemirani,Mohammad Reza Jamali,Masoud Salavati-Niasari.  (2009-09-29)  Simultaneous extraction and preconcentration of uranium and thorium in aqueous samples by new modified mesoporous silica prior to inductively coupled plasma optical emission spectrometry determination..  Talanta,  80  ((1)):  (212-217).  [PMID:19782216]
15. Nilesh R Tawari,Ranjeet Bairwa,M K Ray,M G R Rajan,Mariam S Degani.  (2010-09-21)  Design, synthesis, and biological evaluation of 4-(5-nitrofuran-2-yl)prop-2-en-1-one derivatives as potent antitubercular agents..  Bioorganic & medicinal chemistry letters,  20  ((21)):  (6175-6178).  [PMID:20850299]