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2-苯基喹啉

规格或纯度: 99%
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货号 (SKU) 包装规格 是否现货 价格 数量
P119925-1g
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P119925-5g
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P119925-25g
25g 现货 Stock Image
P119925-100g
100g 现货 Stock Image
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六元杂环化合物 吡啶类

基本描述

英文别名 2-Phenylquinoline|612-96-4|Quinoline, 2-phenyl-|.alpha.-Phenylquinoline|MFCD00011568|2-Phenyl-quinoline|612-73-7|CHEMBL89786|2-phenyl quinoline|Quinoline, phenyl-|2-Phenyl-chinolin|EINECS 210-326-7|PHENYLQUINOLINE|2-Phenylquinoline, 99%|Bionet2_001089|SCH
规格或纯度 99%
英文名称 2-Phenylquinoline
运输条件 常规运输
产品介绍


Product introduction

2-Phenylquinoline is the major quinoline alkaloid of Galipea iongiflora, a Bolivian plant used as treatment for cutaneous leishmaniasis. Antinociceptive properties of 2-phenylquinoline isolated from the bark of Galipea iongiflora against different models of pain in mice were evaluated.


Application

2-Phenylquinoline was used in quantitative structure-activity relationship (QSAR) analyses of estrogen receptor β-selective ligands.

名称和标识符

PubChem SID 488184658
EC号 210-326-7
IUPAC Name 2-phenylquinoline
INCHI InChI=1S/C15H11N/c1-2-6-12(7-3-1)15-11-10-13-8-4-5-9-14(13)16-15/h1-11H
InChi Key FSEXLNMNADBYJU-UHFFFAOYSA-N
Canonical SMILES C1=CC=C(C=C1)C2=NC3=CC=CC=C3C=C2
Isomeric SMILES C1=CC=C(C=C1)C2=NC3=CC=CC=C3C=C2
WGK Germany 3
PubChem CID 71545
分子量 205.25
Reaxy-Rn 130341

化学和物理性质

沸点 363°C
熔点 82-84°C

安全和危险性(GHS)

象形图
ghs07

Harmful

信号词 Warning
危险声明 H315: Causes skin irritation
H319: Causes serious eye irritation
H335: May cause respiratory irritation
预防措施声明 P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P304+P340,P403+P233,P362+P364,P264+P265,P337+P317,P332+P317,P319
WGK Germany 3
Reaxy-Rn 130341
个人防护装备 dust mask type N95 (US), Eyeshields, Gloves

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参考文献

1. A Fournet,M E Ferreira,A Rojas De Arias,S Torres De Ortiz,S Fuentes,H Nakayama,A Schinini,R Hocquemiller.  (1996-11-01)  In vivo efficacy of oral and intralesional administration of 2-substituted quinolines in experimental treatment of new world cutaneous leishmaniasis caused by Leishmania amazonensis..  Antimicrobial agents and chemotherapy,  40  ((11)):  (2447-2451).  [PMID:8913444]
2. Balaji,Ramanathan Muthiah,Sabarinath,Ramamurthy,Chandrasekharan.  (2011-03-29)  Descriptor analysis of estrogen receptor β-selective ligands using 2-phenylquinoline, tetrahydrofluorenone and 3-hydroxy 6H-benzo[c]chromen-6-one scaffolds..  Journal of enzyme inhibition and medicinal chemistry,  26  ((6)):  (831-842).  [PMID:21438712]
3. Wendell Ho-Tin Law,Kam-Keung Leung,Lawrence Cho-Cheung Lee,Che-Shan Poon,Hua-Wei Liu,Kenneth Kam-Wing Lo.  (2014-03-20)  Cyclometalated iridium(III) bipyridyl-phenylenediamine complexes with multicolor phosphorescence: synthesis, electrochemistry, photophysics, and intracellular nitric oxide sensing..  ChemMedChem,  ((6)):  (1316-1329).  [PMID:24643988]
4. Tamara Rodríguez-Cabo,Mohammed Moniruzzaman,Isaac Rodríguez,María Ramil,Rafael Cela,Siew Hua Gan.  (2015-06-05)  Time-of-flight accurate mass spectrometry identification of quinoline alkaloids in honey..  Analytical and bioanalytical chemistry,  407  ((20)):  (6159-6170).  [PMID:26041455]
5. Hye Jeong Yang,Min Jung Kim,Dae Young Kwon,Eun Seon Kang,Suna Kang,Sunmin Park.  (2017-07-09)  Gastroprotective actions of Taraxacum coreanum Nakai water extracts in ethanol-induced rat models of acute and chronic gastritis..  Journal of ethnopharmacology,  208  ():  (84-93).  [PMID:28687507]
6. Diandra Arévalo-Lopéz,Nélida Nina,Juan C Ticona,Ivan Limachi,Efrain Salamanca,Enrique Udaeta,Crispin Paredes,Boris Espinoza,Alcides Serato,David Garnica,Abigail Limachi,Dayana Coaquira,Sarah Salazar,Ninoska Flores,Olov Sterner,Alberto Giménez.  (2018-02-03)  Leishmanicidal and cytotoxic activity from plants used in Tacana traditional medicine (Bolivia)..  Journal of ethnopharmacology,  216  ():  (120-133).  [PMID:29391199]
7. Menghan Zang,Huijuan Su,Lihua Lu,Feng Li.  (2019-06-07)  A split G-quadruplex-specific dinuclear Ir(III) complex for label-free luminescent detection of transcription factor..  Talanta,  202  ():  (259-266).  [PMID:31171179]
8. F Campos-Buzzi,M Fracasso,B K Clasen,J C Ticona,A Gimenez,V Cechinel-Filho.  (2011-01-13)  Evaluation of antinociceptive effects of Galipea longiflora alkaloid extract and major alkaloid 2-phenylquinoline..  Methods and findings in experimental and clinical pharmacology,  32  ((10)):  (707-711).  [PMID:21225005]
9. Mehdi Sharifi-Rad,Patrick Valere Tsouh Fokou,Farukh Sharopov,Miquel Martorell,Adedayo Oluwaseun Ademiluyi,Jovana Rajkovic,Bahare Salehi,Natália Martins,Marcello Iriti,Javad Sharifi-Rad.  (2018-07-19)  Antiulcer Agents: From Plant Extracts to Phytochemicals in Healing Promotion..  Molecules (Basel, Switzerland),  23  ((7)):  ().  [PMID:30018251]
10. Régis Carlos Benvenutti,Cristian Alex Dalla Vecchia,Gelvani Locateli,Patrícia Zanotelli Serpa,Junir Antonio Lutinski,Sinval Adalberto Rodrigues Junior,Vanessa Corralo,Max Vidal Gutiérrez,Wagner Vilegas,Lincon Bordignon Somensi,Bruna Longo,Jessica Ferreira Knihs,Luisa Mota da Silva,Sérgio Faloni de Andrade,Walter Antônio Roman Junior.  (2019-12-15)  Gastroprotective activity of hydroalcoholic extract of the leaves of Urera baccifera in rodents..  Journal of ethnopharmacology,  250  ():  (112473-112473).  [PMID:31836518]