对羧基苯磺酰胺

规格或纯度: 95%

CAS编号: 138-41-0
分子式: C₇H₇NO₄S
分子量: 201.2
Beilstein号: 1875393
EC号: 205-327-4
MDL号: MFCD00007938
PubChem编号: 8739

有货

库存信息

关闭

库存信息

关闭

库存信息

关闭

库存信息

关闭

货号 (SKU)	包装规格	是否现货
S106638-25g	25g	现货
S106638-100g	100g	现货
S106638-250g	250g	现货
S106638-500g	500g	现货

查看相关系列

含硫化合物非杂环砌块

Skip to the end of the images gallery

Skip to the beginning of the images gallery

基本描述

别名	对磺酰胺苯甲酸\|4-羧基苯磺酰胺\|4-磺酰氨基苯甲酸\|卡西尼特
英文别名	4-Sulfamoylbenzoic acid\|Carzenide\|138-41-0\|4-Carboxybenzenesulfonamide\|4-(Aminosulfonyl)benzoic acid\|Benzoic acid, 4-(aminosulfonyl)-\|p-Carboxybenzenesulfonamide\|Carzenid\|Dirnate\|p-Sulfamoylbenzoic acid\|p-Sulfamylbenzoic acid\|Benzoic acid p-sulfamide\|Carz
规格或纯度	95%
英文名称	4-Sulfamylbenzoic acid
运输条件	常规运输
产品介绍	Product Application: Sulfamoylbenzoic acid is a moiety of sulfamyl diuretics or antihypertensive. It is used as an antiviral and an intermediate for the manufacture of frusemide which used as a diuretic and as an antihypertensive.

名称和标识符

PubChem SID	488180873
PubChem SID url	https://pubchem.ncbi.nlm.nih.gov/substance/488180873
EC号	205-327-4
IUPAC Name	4-sulfamoylbenzoic acid
INCHI	InChI=1S/C7H7NO4S/c8-13(11,12)6-3-1-5(2-4-6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12)
InChi Key	UCAGLBKTLXCODC-UHFFFAOYSA-N
Canonical SMILES	C1=CC(=CC=C1C(=O)O)S(=O)(=O)N
Isomeric SMILES	C1=CC(=CC=C1C(=O)O)S(=O)(=O)N
WGK Germany	3
RTECS	DH6820000
PubChem CID	8739
分子量	201.2
Beilstein号	1875393
Reaxy-Rn	1875393

数据库链接

PubChem SID	488180873

化学和物理性质

溶解性	Insoluble in water.
密度	1.536
熔点	285-295°C

安全和危险性（GHS）

象形图	Harmful
信号词	Warning
危险声明	H315: Causes skin irritation H319: Causes serious eye irritation H335: May cause respiratory irritation H302: Harmful if swallowed H312: Harmful in contact with skin H332: Harmful if inhaled
预防措施声明	P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P270,P304+P340,P403+P233,P362+P364,P330,P264+P265,P301+P317,P317,P337+P317,P332+P317,P319
WGK Germany	3
RTECS	DH6820000
Reaxy-Rn	1875393
Merck Index	1876
个人防护装备	Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

质检证书(COA)

质检报告(COA)

输入批号以搜索COA:

可替换产品

产品问答

登录提交问题

查看全部

您提交该产品问题后,我们会在1-2个工作日内给您答复,您可以登录"我的账号",然后点击"我的产品问答"查看答案

参考文献

1. Vullo D, Innocenti A, Nishimori I, Pastorek J, Scozzafava A, Pastoreková S, Supuran CT. (2005) Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides-a new target for the design of antitumor and antiglaucoma drugs?. Bioorg Med Chem Lett, 15 (4): (963-9). [PMID:15686894]
2. Nishimori I, Vullo D, Innocenti A, Scozzafava A, Mastrolorenzo A, Supuran CT. (2005) Carbonic anhydrase inhibitors: inhibition of the transmembrane isozyme XIV with sulfonamides.. Bioorg Med Chem Lett, 15 (17): (3828-33). [PMID:16039848]
3. F Poncelet,M Mercier,J Lederer. (1980-08-01) Saccharin: para forms of some impurities are not mutagenic in Salmonella typhimurium.. Food and cosmetics toxicology, 18 ((4)): (453-453). [PMID:7007186]
4. K J Ullrich,G Fritzsch,G Rumrich,C David. (1994-05-01) Polysubstrates: substances that interact with renal contraluminal PAH, sulfate, and NMeN transport: sulfamoyl-, sulfonylurea-, thiazide- and benzeneamino-carboxylate (nicotinate) compounds.. The Journal of pharmacology and experimental therapeutics, 269 ((2)): (684-692). [PMID:8182536]
5. K Eckhardt,M T King,E Gocke,D Wild. (1980-11-01) Mutagenicity study of Remsen-Fahlberg saccharin and contaminants.. Toxicology letters, 7 ((1)): (51-60). [PMID:6794189]
6. Daniela Vullo,Juha Voipio,Alessio Innocenti,Claudio Rivera,Harri Ranki,Andrea Scozzafava,Kai Kaila,Claudiu T Supuran. (2005-02-03) Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides.. Bioorganic & medicinal chemistry letters, 15 ((4)): (971-976). [PMID:15686895]
7. Jean-Yves Winum,Jean-Michel Dogné,Angela Casini,Xavier de Leval,Jean-Louis Montero,Andrea Scozzafava,Daniela Vullo,Alessio Innocenti,Claudiu T Supuran. (2005-03-18) Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/membrane-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating hydrazino moieties.. Journal of medicinal chemistry, 48 ((6)): (2121-2125). [PMID:15771455]
8. Isao Nishimori,Daniela Vullo,Alessio Innocenti,Andrea Scozzafava,Antonio Mastrolorenzo,Claudiu T Supuran. (2005-11-24) Carbonic anhydrase inhibitors. The mitochondrial isozyme VB as a new target for sulfonamide and sulfamate inhibitors.. Journal of medicinal chemistry, 48 ((24)): (7860-7866). [PMID:16302824]
9. Isao Nishimori,Daniela Vullo,Tomoko Minakuchi,Kaori Morimoto,Saburo Onishi,Andrea Scozzafava,Claudiu T Supuran. (2006-02-07) Carbonic anhydrase inhibitors: cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacter pylori.. Bioorganic & medicinal chemistry letters, 16 ((8)): (2182-2188). [PMID:16459077]
10. Isao Nishimori,Tomoko Minakuchi,Kaori Morimoto,Shuichi Sano,Saburo Onishi,Hiroaki Takeuchi,Daniela Vullo,Andrea Scozzafava,Claudiu T Supuran. (2006-03-17) Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs.. Journal of medicinal chemistry, 49 ((6)): (2117-2126). [PMID:16539401]
11. Isao Nishimori,Tomoko Minakuchi,Saburo Onishi,Daniela Vullo,Andrea Scozzafava,Claudiu T Supuran. (2007-01-19) Carbonic anhydrase inhibitors. DNA cloning, characterization, and inhibition studies of the human secretory isoform VI, a new target for sulfonamide and sulfamate inhibitors.. Journal of medicinal chemistry, 50 ((2)): (381-388). [PMID:17228881]
12. Brendan L Wilkinson,Laurent F Bornaghi,Anthony D Wright,Todd A Houston,Sally-Ann Poulsen. (2007-01-30) Anti-mycobacterial activity of a bis-sulfonamide.. Bioorganic & medicinal chemistry letters, 17 ((5)): (1355-1357). [PMID:17258454]
13. Isao Nishimori,Tomoko Minakuchi,Takuhiro Kohsaki,Saburo Onishi,Hiroaki Takeuchi,Daniela Vullo,Andrea Scozzafava,Claudiu T Supuran. (2007-05-08) Carbonic anhydrase inhibitors: the beta-carbonic anhydrase from Helicobacter pylori is a new target for sulfonamide and sulfamate inhibitors.. Bioorganic & medicinal chemistry letters, 17 ((13)): (3585-3594). [PMID:17482815]
14. Semra Isik,Feray Kockar,Meltem Aydin,Oktay Arslan,Ozen Ozensoy Guler,Alessio Innocenti,Andrea Scozzafava,Claudiu T Supuran. (2009-01-07) Carbonic anhydrase inhibitors: inhibition of the beta-class enzyme from the yeast Saccharomyces cerevisiae with sulfonamides and sulfamates.. Bioorganic & medicinal chemistry, 17 ((3)): (1158-1163). [PMID:19124253]
15. Mika Hilvo,Anna Maria Salzano,Alessio Innocenti,Markku S Kulomaa,Andrea Scozzafava,Andrea Scaloni,Seppo Parkkila,Claudiu T Supuran. (2009-02-06) Cloning, expression, post-translational modifications and inhibition studies on the latest mammalian carbonic anhydrase isoform, CA XV.. Journal of medicinal chemistry, 52 ((3)): (646-654). [PMID:19193158]
16. Oral Oltulu,Mehmet M Yaşar,Erol Eroğlu. (2009-03-24) A QSAR study on relationship between structure of sulfonamides and their carbonic anhydrase inhibitory activity using the eigenvalue (EVA) method.. European journal of medicinal chemistry, 44 ((9)): (3439-3444). [PMID:19303173]
17. Tomoko Minakuchi,Isao Nishimori,Daniela Vullo,Andrea Scozzafava,Claudiu T Supuran. (2009-03-26) Molecular cloning, characterization, and inhibition studies of the Rv1284 beta-carbonic anhydrase from Mycobacterium tuberculosis with sulfonamides and a sulfamate.. Journal of medicinal chemistry, 52 ((8)): (2226-2232). [PMID:19317447]
18. Isao Nishimori,Tomoko Minakuchi,Daniela Vullo,Andrea Scozzafava,Alessio Innocenti,Claudiu T Supuran. (2009-04-03) Carbonic anhydrase inhibitors. Cloning, characterization, and inhibition studies of a new beta-carbonic anhydrase from Mycobacterium tuberculosis.. Journal of medicinal chemistry, 52 ((9)): (3116-3120). [PMID:19338333]
19. Alessio Innocenti,Rebecca A Hall,Christine Schlicker,Andrea Scozzafava,Clemens Steegborn,Fritz A Mühlschlegel,Claudiu T Supuran. (2009-05-20) Carbonic anhydrase inhibitors. Inhibition and homology modeling studies of the fungal beta-carbonic anhydrase from Candida albicans with sulfonamides.. Bioorganic & medicinal chemistry, 17 ((13)): (4503-4509). [PMID:19450983]
20. Anthony Bertucci,Alessio Innocenti,Didier Zoccola,Andrea Scozzafava,Sylvie Tambutté,Claudiu T Supuran. (2009-06-13) Carbonic anhydrase inhibitors. Inhibition studies of a coral secretory isoform by sulfonamides.. Bioorganic & medicinal chemistry, 17 ((14)): (5054-5058). [PMID:19520577]
21. Fabrizio Carta,Alfonso Maresca,Adrian Suarez Covarrubias,Sherry L Mowbray,T Alwyn Jones,Claudiu T Supuran. (2009-10-23) Carbonic anhydrase inhibitors. Characterization and inhibition studies of the most active beta-carbonic anhydrase from Mycobacterium tuberculosis, Rv3588c.. Bioorganic & medicinal chemistry letters, 19 ((23)): (6649-6654). [PMID:19846301]
22. Pascale Joseph,François Turtaut,Safia Ouahrani-Bettache,Jean-Louis Montero,Isao Nishimori,Tomoko Minakuchi,Daniela Vullo,Andrea Scozzafava,Stephan Köhler,Jean-Yves Winum,Claudiu T Supuran. (2010-02-18) Cloning, characterization, and inhibition studies of a beta-carbonic anhydrase from Brucella suis.. Journal of medicinal chemistry, 53 ((5)): (2277-2285). [PMID:20158185]
23. Anthony Bertucci,Alessio Innocenti,Andrea Scozzafava,Sylvie Tambutté,Didier Zoccola,Claudiu T Supuran. (2011-01-07) Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata.. Bioorganic & medicinal chemistry letters, 21 ((2)): (710-714). [PMID:21208801]
24. Pascale Joseph,Safia Ouahrani-Bettache,Jean-Louis Montero,Isao Nishimori,Tomoko Minakuchi,Daniela Vullo,Andrea Scozzafava,Jean-Yves Winum,Stephan Köhler,Claudiu T Supuran. (2011-01-22) A new β-carbonic anhydrase from Brucella suis, its cloning, characterization, and inhibition with sulfonamides and sulfamates, leading to impaired pathogen growth.. Bioorganic & medicinal chemistry, 19 ((3)): (1172-1178). [PMID:21251841]
25. Isao Nishimori,Tomoko Minakuchi,Daniela Vullo,Andrea Scozzafava,Claudiu T Supuran. (2011-07-16) Inhibition studies of the β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium with sulfonamides and sulfamates.. Bioorganic & medicinal chemistry, 19 ((16)): (5023-5030). [PMID:21757360]
26. . (2011-09-16) New bitter blocker discovered, study finds.. Journal of the American Dental Association (1939), 142 ((8)): (901-901). [PMID:21919220]
27. Anna Ohradanova,Daniela Vullo,Silvia Pastorekova,Jaromir Pastorek,Daniel J Jackson,Gert Wörheide,Claudiu T Supuran. (2012-01-31) Cloning, characterization and sulfonamide inhibition studies of an α-carbonic anhydrase from the living fossil sponge Astrosclera willeyana.. Bioorganic & medicinal chemistry, 20 ((4)): (1403-1410). [PMID:22285172]
28. Massinissa Si Mehand,Bala Srinivasan,Gregory De Crescenzo. (2015-10-31) Optimizing Multiple Analyte Injections in Surface Plasmon Resonance Biosensors with Analytes having Different Refractive Index Increments.. Scientific reports, 5 (): (15855-15855). [PMID:26515024]
29. Tiphaine Rogez-Florent,Catherine Foulon,Anne-Sophie Drucbert,Nadège Schifano,Perrine Six,Stéphanie Devassine,Patrick Depreux,Pierre-Marie Danzé,Laurence Goossens,Cécile Danel,Jean-François Goossens. (2017-01-23) Chiral separation of new sulfonamide derivatives and evaluation of their enantioselective affinity for human carbonic anhydrase II by microscale thermophoresis and surface plasmon resonance.. Journal of pharmaceutical and biomedical analysis, 137 (): (113-122). [PMID:28110167]
30. Daniel J Orton,Malak M Tfaily,Ronald J Moore,Brian L LaMarche,Xueyun Zheng,Thomas L Fillmore,Rosalie K Chu,Karl K Weitz,Matthew E Monroe,Ryan T Kelly,Richard D Smith,Erin S Baker. (2017-11-22) A Customizable Flow Injection System for Automated, High Throughput, and Time Sensitive Ion Mobility Spectrometry and Mass Spectrometry Measurements.. Analytical chemistry, 90 ((1)): (737-744). [PMID:29161511]
31. Sally-Ann Poulsen,Laurent F Bornaghi,Peter C Healy. (2005-10-11) Synthesis and structure-activity relationships of novel benzene sulfonamides with potent binding affinity for bovine carbonic anhydrase II.. Bioorganic & medicinal chemistry letters, 15 ((24)): (5429-5433). [PMID:16213706]
32. Isao Nishimori,Tomoko Minakuchi,Saburo Onishi,Daniela Vullo,Alessandro Cecchi,Andrea Scozzafava,Claudiu T Supuran. (2007-09-11) Carbonic anhydrase inhibitors: cloning, characterization, and inhibition studies of the cytosolic isozyme III with sulfonamides.. Bioorganic & medicinal chemistry, 15 ((23)): (7229-7236). [PMID:17826101]
33. Shinya Tsukiji,Masayoshi Miyagawa,Yousuke Takaoka,Tomonori Tamura,Itaru Hamachi. (2009-03-31) Ligand-directed tosyl chemistry for protein labeling in vivo.. Nature chemical biology, 5 ((5)): (341-343). [PMID:19330012]

对羧基苯磺酰胺

库存信息

库存信息

库存信息

库存信息

基本描述

名称和标识符

数据库链接

化学和物理性质

安全和危险性（GHS）

质检证书(COA)

质检报告(COA)

相关文档

质检报告COA

可替换产品

产品问答

产品问答

参考文献