Silvestrol,抑制剂
- CAS编号: 697235-38-4
- 分子式: C34H38O13
- 分子量: 654.66
- PubChem编号: 11787114
库存信息
货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
---|---|---|---|---|
S126127-1mg |
1mg | 期货 | |
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货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
---|---|---|---|---|
S126127-1mg |
1mg | 期货 | |
英文别名 | silvestrol|697235-38-4|(-)-silvestrol|Silvestrol [WHO-DD]|KK3Y3KN5BV|CHEMBL555196|CHEBI:66484|1H-Cyclopenta(b)benzofuran-2-carboxylic acid, 6-(((2S,3R,6R)-6-((1R)-1,2-dihydroxyethyl)-3-methoxy-1,4-dioxan-2-yl)oxy)-2,3,3a,8b-tetrahydro-1,8b-dihydroxy-8-met |
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规格或纯度 | ≥99% |
英文名称 | Silvestrol |
生化机理 |
Silvestrol((-)-Silvestrol) is the novel cyclopenta[b]benzofuran, silvestrol, isolated from the fruits and twigs of Aglaia foveolata. Silvestrol((-)-Silvestrol) has been found to exhibit very potent in vitro cytotoxic activity against several human cancer cell lines. Furthermore,Silvestrol((-)-Silvestrol) was active in the in vivo P388 murine leukemia model. |
储存温度 | -20°C储存 |
运输条件 | 超低温冰袋运输 |
IUPAC Name | methyl (1R,2R,3S,3aR,8bS)-6-[[(2S,3R,6R)-6-[(1R)-1,2-dihydroxyethyl]-3-methoxy-1,4-dioxan-2-yl]oxy]-1,8b-dihydroxy-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate |
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INCHI | InChI=1S/C34H38O13/c1-40-20-12-10-19(11-13-20)34-27(18-8-6-5-7-9-18)26(30(38)42-3)29(37)33(34,39)28-23(41-2)14-21(15-24(28)47-34)45-32-31(43-4)44-17-25(46-32)22(36)16-35/h5-15,22,25-27,29,31-32,35-37,39H,16-17H2,1-4H3/t22-,25-,26-,27-,29-,31-,32-,33+,34+/m1/s1 |
InChi Key | GVKXFVCXBFGBCD-QKDMMWSPSA-N |
Canonical SMILES | COC1C(OC(CO1)C(CO)O)OC2=CC3=C(C(=C2)OC)C4(C(C(C(C4(O3)C5=CC=C(C=C5)OC)C6=CC=CC=C6)C(=O)OC)O)O |
Isomeric SMILES | CO[C@H]1[C@@H](O[C@H](CO1)[C@@H](CO)O)OC2=CC3=C(C(=C2)OC)[C@@]4([C@@H]([C@@H]([C@H]([C@@]4(O3)C5=CC=C(C=C5)OC)C6=CC=CC=C6)C(=O)OC)O)O |
PubChem CID | 11787114 |
分子量 | 654.66 |
溶解性 | DMSO |
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