噻菌唑, 微管蛋白抑制剂

规格或纯度: 98%

CAS编号: 148-79-8
分子式: C₁₀H₇N₃S
分子量: 201.25
Beilstein号: 611403
EC号: 205-725-8
MDL号: MFCD00005587
PubChem编号: 5430

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货号 (SKU)	包装规格	是否现货
T109875-5g	5g	现货
T109875-25g	25g	现货
T109875-100g	100g	现货
T109875-500g	500g	现货

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基本描述

别名	噻苯唑\|2-(4-噻唑基)苯并咪唑\|噻苯咪唑\|噻菌灵
英文别名	thiabendazole\|148-79-8\|Tiabendazole\|Mintezol\|2-(4-Thiazolyl)benzimidazole\|Thiabenzole\|Equizole\|Minzolum\|Omnizole\|Lombristop\|Thibenzole\|Tiabendazol\|Nemapan\|Thiabendazol\|Bovizole\|Mintesol\|Thibenzol\|Pitrizet\|Tebuzate\|Tiabenda\|Eprofil\|Mertec\|Mertect\|Mycozol\|P
规格或纯度	98%
英文名称	Thiabendazole
生化机理	Thiabendazole inhibits anaerobic respiration at the level of mitochondrial helminth-specific enzyme. It acts as a quinol-fumarate reductase (QFR) inhibitor in ,C. jejuni and H. pylori, blocking quinol oxidation to quinone. Thiabendazole suppresses egg and larval production and may inhibit the subsequent development of eggs and larvae which are passed in feces2. A proposed route of biotransformation of thiabendazole is the CYP1A2-catalyzed hydroxylation to 5-hydroxythiabendazole, which is metabolized to glucuronide and sulfate conjμgates.
应用	内吸性杀菌剂。能防止多种植物的真菌病害，用于处理收获后的水果和蔬菜，可防止贮存中发生的上些病害，目前国内外已广泛应用。
运输条件	常规运输
产品介绍	白色至灰白色无味粉末。不溶于水，微溶于醇、丙酮，易溶于乙醚、氯仿。内吸性杀菌剂。能防止多种植物的真菌病害，用于处理收获后的水果和蔬菜，可防止贮存中发生的上些病害，目前国内外已广泛应用。 Thiabendazole (TBZ) is a broad-spectrum antihelminthic and is used to treat parasitic infections in humans. It is used as an agricultural fungicide and as a food preservative. Thiabendazole has been used as a heavy metal chelating detoxification agent. It is used clinically to treat threadworm, cutaneous larva migrans, visceral larva migrans, and trichinosis.

产品属性

ALogP	2.5

名称和标识符

EC号	205-725-8
IUPAC Name	4-(1H-benzimidazol-2-yl)-1,3-thiazole
INCHI	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)
InChi Key	WJCNZQLZVWNLKY-UHFFFAOYSA-N
Canonical SMILES	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3
Isomeric SMILES	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3
WGK Germany	2
RTECS	DE0700000
PubChem CID	5430
UN Number	3077
Packing Group	III
分子量	201.25
Beilstein号	611403

化学和物理性质

溶解性	Soluble in ethanol (1 mg/ml), DMF (50 mg/ml), chlorinated hydrocarbons (slightly), DMSO (40 mg/ml), and water (<1 mg/ml).
密度	1.406
熔点	304-305°C

安全和危险性（GHS）

象形图	Environmental Hazard
信号词	Warning
危险声明	H400: Very toxic to aquatic life H410: Very toxic to aquatic life with long lasting effects
预防措施声明	P273,P501,P391
WGK Germany	2
RTECS	DE0700000
Class	9
Merck Index	9289
个人防护装备	Eyeshields,Gloves

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参考文献

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噻菌唑, 微管蛋白抑制剂

库存信息

库存信息

库存信息

库存信息

基本描述

产品属性

名称和标识符

化学和物理性质

安全和危险性（GHS）

质检证书(COA)

质检报告(COA)

相关文档

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参考文献